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2PLV
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BU of 2plv by Molmil
STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
Descriptor: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
Authors:Filman, D.J, Hogle, J.M.
Deposit date:1989-10-17
Release date:1989-10-17
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
6NEF
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BU of 6nef by Molmil
Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens
Descriptor: C-type cytochrome OmcS, HEME C, MAGNESIUM ION
Authors:Filman, D.J, Marino, S.F, Ward, J.E, Yang, L, Mester, Z, Bullitt, E, Lovley, D.R, Strauss, M.
Deposit date:2018-12-17
Release date:2019-07-03
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.
Commun Biol, 2, 2019
4DFR
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BU of 4dfr by Molmil
CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J.
Deposit date:1982-06-25
Release date:1982-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
3DFR
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BU of 3dfr by Molmil
CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
Descriptor: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J.
Deposit date:1982-06-25
Release date:1982-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
1EV1
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BU of 1ev1 by Molmil
ECHOVIRUS 1
Descriptor: ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID
Authors:Wien, M.W, Filman, D.J, Hogle, J.M.
Deposit date:1997-12-02
Release date:1999-01-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure determination of echovirus 1.
Acta Crystallogr.,Sect.D, 54, 1998
9F5S
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BU of 9f5s by Molmil
EVA71 E096A native particle
Descriptor: SPHINGOSINE, VP0, VP1, ...
Authors:Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S.
Deposit date:2024-04-30
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Reappraisal of the mechanism of the enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate
To Be Published
9F6A
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BU of 9f6a by Molmil
EVA71 E096A native particle
Descriptor: SPHINGOSINE, VP0, VP1, ...
Authors:Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S.
Deposit date:2024-04-30
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Reappraisal of the mechanism of the enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate
To Be Published
1QBP
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BU of 1qbp by Molmil
CRYSTAL STRUCTURE OF A BROMINATED RNA HELIX WITH FOUR MISMATCHED BASE PAIRS
Descriptor: 5'-R(*UP*GP*(CBV)P*(CBV)P*AP*GP*UP*UP*CP*GP*CP*UP*GP*GP*C)-3'
Authors:Anderson, A.C, O'Neil, R.H, Filman, D.J, Frederick, C.A.
Deposit date:1999-04-26
Release date:1999-11-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a brominated RNA helix with four mismatched base pairs: An investigation into RNA conformational variability.
Biochemistry, 38, 1999
5A3G
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BU of 5a3g by Molmil
Structure of herpesvirus nuclear egress complex subunit M50
Descriptor: M50
Authors:Leigh, K.E, Boeszoermenyi, A, Mansueto, M.S, Sharma, M, Filman, D.J, Coen, D.M, Wagner, G, Hogle, J.M, Arthanari, H.
Deposit date:2015-06-01
Release date:2015-07-15
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structure of a Herpesvirus Nuclear Egress Complex Subunit Reveals an Interaction Groove that is Essential for Viral Replication
Proc.Natl.Acad.Sci.USA, 112, 2015
1HXS
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BU of 1hxs by Molmil
CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION
Descriptor: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
Authors:Miller, S.T, Hogle, J.M, Filman, D.J.
Deposit date:2001-01-16
Release date:2002-01-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.
J.Mol.Biol., 307, 2001
1VBB
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BU of 1vbb by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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BU of 1vbc by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBE
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BU of 1vbe by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBA
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BU of 1vba by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBD
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BU of 1vbd by Molmil
POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1PO2
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BU of 1po2 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PO1
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BU of 1po1 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PVC
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BU of 1pvc by Molmil
REFINEMENT OF THE SABIN STRAIN OF TYPE 3 POLIOVIRUS AT 2.4 ANGSTROMS AND THE CRYSTAL STRUCTURES OF ITS VARIANTS AT 2.9 ANGSTROMS RESOLUTION
Descriptor: MYRISTIC ACID, POLIOVIRUS TYPE 3, SABIN STRAIN, ...
Authors:Syed, R, Filman, D.J, Hogle, J.M.
Deposit date:1995-03-30
Release date:1995-09-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refinement of the Sabin Strain of Type 3 Poliovirus at 2.4 Angstroms and the Crystal Structures of its Variants at 2.9 Angstroms Resolution
To be Published
1AL2
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BU of 1al2 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-06-09
Release date:1997-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1POV
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BU of 1pov by Molmil
ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION
Descriptor: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE
Authors:Basavappa, R, Filman, D.J, Hogle, J.M.
Deposit date:1995-08-10
Release date:1995-12-07
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Protein Sci., 3, 1994
1AR7
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BU of 1ar7 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR8
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BU of 1ar8 by Molmil
P1/MAHONEY POLIOVIRUS, MUTANT P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1ASJ
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BU of 1asj by Molmil
P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR6
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BU of 1ar6 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR9
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BU of 1ar9 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997

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