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1E7K
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BU of 1e7k by Molmil
Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment
Descriptor: 15.5 KD RNA BINDING PROTEIN, RNA (5'-R(*GP*CP*CP*AP*AP*UP*GP*AP*GP*GP*UP*UP*UP* AP*UP*CP*CP*GP*AP*GP*G*C(-3')
Authors:Vidovic, I, Nottrott, S, Harthmuth, K, Luhrmann, R, Ficner, R.
Deposit date:2000-08-29
Release date:2001-02-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment
Mol.Cell, 6, 2000
1N93
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BU of 1n93 by Molmil
Crystal Structure of the Borna Disease Virus Nucleoprotein
Descriptor: p40 nucleoprotein
Authors:Rudolph, M.G, Kraus, I, Dickmanns, A, Garten, W, Ficner, R.
Deposit date:2002-11-22
Release date:2003-10-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of the Borna Disease Virus nucleoprotein
Structure, 11, 2003
1EFZ
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BU of 1efz by Molmil
MUTAGENESIS AND CRYSTALLOGRAPHIC STUDIES OF ZYMOMONAS MOBILIS TRNA-GUANINE TRANSGLYCOSYLASE TO ELUCIDATE THE ROLE OF SERINE 103 FOR ENZYMATIC ACTIVITY
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Gradler, U, Ficner, R, Garcia, G.A, Stubbs, M.T, Klebe, G, Reuter, K.
Deposit date:2000-02-11
Release date:2000-03-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity.
FEBS Lett., 454, 1999
5HSA
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BU of 5hsa by Molmil
Alcohol Oxidase AOX1 from Pichia Pastoris
Descriptor: ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, Alcohol oxidase 1, CALCIUM ION, ...
Authors:Neumann, P, Ficner, R, Feussner, I, Koch, C.
Deposit date:2016-01-25
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of Alcohol Oxidase from Pichia pastoris.
Plos One, 11, 2016
3CTR
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BU of 3ctr by Molmil
Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Poly(A)-specific ribonuclease PARN
Authors:Monecke, T, Schell, S, Dickmanns, A, Ficner, R.
Deposit date:2008-04-14
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.
J.Mol.Biol., 382, 2008
7B51
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BU of 7b51 by Molmil
Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528
Descriptor: BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ...
Authors:Shaikhqasem, A, Ficner, R.
Deposit date:2020-12-03
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP.
Acta Crystallogr.,Sect.F, 77, 2021
1MZW
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BU of 1mzw by Molmil
Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K peptide
Descriptor: U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein
Authors:Reidt, U, Wahl, M.C, Horowitz, D.S, Luehrmann, R, Ficner, R.
Deposit date:2002-10-10
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide
J.Mol.Biol., 331, 2003
1ENU
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BU of 1enu by Molmil
A new target for shigellosis: Rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase
Descriptor: 4-AMINOPHTHALHYDRAZIDE, TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Gradler, U, Gerber, H.D, Goodenough-Lashua, D.M, Garcia, G.A, Ficner, R, Reuter, K, Stubbs, M.T, Klebe, G.
Deposit date:2000-03-21
Release date:2000-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase.
J.Mol.Biol., 306, 2001
5O5S
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BU of 5o5s by Molmil
X-ray crystal structure of the RapZ C-terminal domain from Escherichia coli
Descriptor: MALONATE ION, RNase adapter protein RapZ
Authors:Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F.
Deposit date:2017-06-02
Release date:2017-08-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
5O5O
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BU of 5o5o by Molmil
X-ray crystal structure of RapZ from Escherichia coli (P32 space group)
Descriptor: RNase adapter protein RapZ, SULFATE ION
Authors:Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F.
Deposit date:2017-06-02
Release date:2017-08-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
5O5Q
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BU of 5o5q by Molmil
X-ray crystal structure of RapZ from Escherichia coli (P3221 space group)
Descriptor: RNase adapter protein RapZ, SULFATE ION
Authors:Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F.
Deposit date:2017-06-02
Release date:2017-08-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
Deposit date:2015-09-01
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
2VCG
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BU of 2vcg by Molmil
Crystal structure of a HDAC-like protein HDAH from Bordetella sp. with the bound inhibitor ST-17
Descriptor: CHLORIDE ION, GLYCEROL, HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE, ...
Authors:Dickmanns, A, Strasser, A, Ficner, R.
Deposit date:2007-09-24
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Phenylalanine-Containing Hydroxamic Acids as Selective Inhibitors of Class Iib Histone Deacetylases (Hdacs).
Bioorg.Med.Chem., 16, 2008
2GH6
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BU of 2gh6 by Molmil
Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound
Descriptor: 9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ...
Authors:Nielsen, T.K, Hildmann, C, Riester, D, Wegener, D, Schwienhorst, A, Ficner, R.
Deposit date:2006-03-26
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor.
Acta Crystallogr.,Sect.F, 63, 2007
2QNA
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BU of 2qna by Molmil
Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65)
Descriptor: Importin subunit beta-1, SULFATE ION, Snurportin-1
Authors:Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R.
Deposit date:2007-07-18
Release date:2008-04-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus.
J.Mol.Biol., 374, 2007
1PUD
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BU of 1pud by Molmil
TRNA-GUANINE TRANSGLYCOSYLASE
Descriptor: TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Romier, C, Reuter, K, Suck, D, Ficner, R.
Deposit date:1996-06-28
Release date:1997-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
EMBO J., 15, 1996
5J8N
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BU of 5j8n by Molmil
Exonuclease III homologue Mm3148 from Methanosarcina mazei
Descriptor: Exodeoxyribonuclease III, MAGNESIUM ION, TETRAETHYLENE GLYCOL
Authors:Lakomek, K, Dickmanns, A, Ficner, R.
Deposit date:2016-04-08
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structure of the archael ExoIII homologue Mm3148 at 1.4 Angstrom
To Be Published
1ALL
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BU of 1all by Molmil
ALLOPHYCOCYANIN
Descriptor: ALLOPHYCOCYANIN, PHYCOCYANOBILIN
Authors:Brejc, K, Ficner, R, Huber, R, Steinbacher, S.
Deposit date:1995-03-01
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution.
J.Mol.Biol., 249, 1995
1QGV
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BU of 1qgv by Molmil
HUMAN SPLICEOSOMAL PROTEIN U5-15KD
Descriptor: SPLICEOSOMAL PROTEIN U5-15KD
Authors:Reuter, K, Nottrott, S, Fabrizio, P, Luehrmann, R, Ficner, R.
Deposit date:1999-05-06
Release date:1999-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein.
J.Mol.Biol., 294, 1999
5DTU
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BU of 5dtu by Molmil
Crystal structure of the RNA-helicase Prp28 from Chaetomium thermophilum bound to ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Prp28
Authors:Tauchert, M.J, Ficner, R.
Deposit date:2015-09-18
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.199 Å)
Cite:Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 72, 2016
5EK8
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BU of 5ek8 by Molmil
Crystal structure of a 9R-lipoxygenase from Cyanothece PCC8801 at 2.7 Angstroms
Descriptor: FE (II) ION, Lipoxygenase, SODIUM ION
Authors:Feussner, I, Ficner, R, Neumann, P, Newie, J, Andreou, A, Einsle, O.
Deposit date:2015-11-03
Release date:2015-12-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition.
J.Lipid Res., 57, 2016
6TVO
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BU of 6tvo by Molmil
Human CRM1-RanGTP in complex with Leptomycin B
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Shaikhqasem, A, Ficner, R.
Deposit date:2020-01-10
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1.
J.Med.Chem., 63, 2020
5D0U
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BU of 5d0u by Molmil
Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Tauchert, M.J, Ficner, R.
Deposit date:2015-08-03
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.919 Å)
Cite:Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 72, 2016
1QR0
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BU of 1qr0 by Molmil
CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX
Descriptor: 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION
Authors:Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R.
Deposit date:1999-06-17
Release date:1999-12-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.
EMBO J., 18, 1999
1V0E
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BU of 1v0e by Molmil
Endosialidase of Bacteriophage K1F
Descriptor: ENDO-ALPHA-SIALIDASE, PHOSPHATE ION
Authors:Stummeyer, K, Dickmanns, A, Muehlenhoff, M, Gerady-Schahn, R, Ficner, R.
Deposit date:2004-03-28
Release date:2004-12-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Nat.Struct.Mol.Biol., 12, 2005

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