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2YAK
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STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV)
分子名称:DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4
著者Feng, L., Geisselbrecht, Y., Blanck, S., Wilbuer, A., Atilla-Gokcumen, G.E., Filippakopoulos, P., Kraeling, K., Celik, M.A., Harms, K., Maksimoska, J., Marmorstein, R., Frenking, G., Knapp, S., Essen, L.-O., Meggers, E.
登録日2011-02-23
公開日2011-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors.
J.Am.Chem.Soc., 133, 2011
1Y01
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CRYSTAL STRUCTURE OF AHSP BOUND TO FE(II) ALPHA-HEMOGLOBIN
分子名称:Alpha-hemoglobin stabilizing protein, Hemoglobin alpha chain, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Feng, L., Gell, D.A., Zhou, S., Gu, L., Gow, A.J., Weiss, M.J., Mackay, J.P., Shi, Y.
登録日2004-11-14
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin.
Cell(Cambridge,Mass.), 119, 2004
1Z8U
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CRYSTAL STRUCTURE OF OXIDIZED ALPHA HEMOGLOBIN BOUND TO AHSP
分子名称:Alpha-hemoglobin stabilizing protein, Hemoglobin alpha chain, PROTOPORPHYRIN IX CONTAINING FE
著者Feng, L., Zhou, S., Gu, L., Gell, D.A., Mackay, J.P., Weiss, M.J., Gow, A.J., Shi, Y.
登録日2005-03-31
公開日2005-06-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem.
Nature, 435, 2005
4LPC
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CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEPTAOSE
分子名称:1,4-alpha-glucan branching enzyme GlgB, ALPHA-D-GLUCOSE, GLYCEROL, ...
著者Feng, L., Geiger, J.H.
登録日2013-07-16
公開日2015-04-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides.
Biochemistry, 54, 2015
4LQ1
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CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEXAOSE
分子名称:1,4-alpha-glucan branching enzyme GlgB, BETA-D-GLUCOSE, ALPHA-D-GLUCOSE, ...
著者Feng, L., Geiger, J.H.
登録日2013-07-17
公開日2015-04-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides.
Biochemistry, 54, 2015
3AFK
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CRYSTAL STRUCTURE OF AGROCYBE AEGERITA LECTIN AAL COMPLEXED WITH THOMSEN-FRIEDENREICH ANTIGEN
分子名称:Anti-tumor lectin, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Feng, L., Li, D., Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3C
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CRYSTAL STRUCTURE OF AGROCYBE AEGERITA LECTIN AAL COMPLEXED WITH P-NITROPHENYL TF DISACCHARIDE
分子名称:Anti-tumor lectin, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Feng, L., Li, D., Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3E
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CRYSTAL STRUCTURE OF AGROCYBE AEGERITA LECTIN AAL MUTANT E66A COMPLEXED WITH P-NITROPHENYL THOMSEN-FRIEDENREICH DISACCHARIDE
分子名称:Anti-tumor lectin, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Feng, L., Li, D., Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3O
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CRYSTAL STRUCTURE OF AGROCYBE AEGERITA LECTIN AAL MUTANT R85A COMPLEXED WITH P-NITROPHENYL TF DISACCHARIDE
分子名称:Anti-tumor lectin, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Feng, L., Li, D., Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3Q
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CRYSTAL STRUCTURE OF AGROCYBE AEGERITA LECTIN AAL COMPLEXED WITH GANGLOSIDES GM1 PENTASACCHARIDE
分子名称:Anti-tumor lectin, BETA-D-GALACTOSE, N-ACETYL-D-GALACTOSAMINE, ...
著者Feng, L., Li, D., Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3NZ4
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CRYSTAL STRUCTURE OF A TAXUS PHENYLALANINE AMINOMUTASE
分子名称:Phenylalanine ammonia-lyase, PHENYLETHYLENECARBOXYLIC ACID
著者Feng, L., Geiger, J.H.
登録日2010-07-16
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Mechanistic, mutational, and structural evaluation of a taxus phenylalanine aminomutase.
Biochemistry, 50, 2011
3ORG
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CRYSTAL STRUCTURE OF A EUKARYOTIC CLC TRANSPORTER
分子名称:CmCLC, CHLORIDE ION
著者Feng, L., MacKinnon, R.
登録日2010-09-07
公開日2010-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
Science, 330, 2010
4FG6
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STRUCTURE OF ECCLC E148A MUTANT IN GLUTAMATE
分子名称:H(+)/Cl(-) exchange transporter ClcA, Fab fragment (Heavy chain), Fab fragment (Light chain)
著者Feng, L., MacKinnon, R.
登録日2012-06-04
公開日2012-07-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.019 Å)
主引用文献Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GVM
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN A128T MUTANT COMPLEXED WITH ALLOSTERIC INHIBITOR
分子名称:Gag-Pol polyprotein, ARSENIC, (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid
著者Feng, L., Kvaratskhelia, M.
登録日2012-08-30
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4GW6
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN COMPLEXED WITH ALLOSTERIC INHIBITOR
分子名称:Gag-Pol polyprotein, ARSENIC, (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid
著者Feng, L., Kvaratskhelia, M.
登録日2012-08-31
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4JLH
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN A128T MUTANT COMPLEXED WITH ALLOSTERIC INHIBITOR
分子名称:HIV-1 Integrase catalytic core domain, (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, SULFATE ION
著者Feng, L., Kvaratskhelia, M.
登録日2013-03-12
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
5E6Y
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CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH ALPHA CYCLODEXTRIN
分子名称:1,4-alpha-glucan branching enzyme GlgB, ALPHA-CYCLODEXTRIN (CYCLOHEXA-AMYLOSE), GLYCEROL
著者Feng, L., Nosrati, M., Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
5E6Z
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CRYSTAL STRUCTURE OF ECOLI BRANCHING ENZYME WITH BETA CYCLODEXTRIN
分子名称:1,4-alpha-glucan branching enzyme GlgB, BETA-CYCLODEXTRIN, GLYCEROL
著者Feng, L., Nosrati, M., Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
5E70
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CRYSTAL STRUCTURE OF ECOLI BRANCHING ENZYME WITH GAMMA CYCLODEXTRIN
分子名称:1,4-alpha-glucan branching enzyme GlgB, gamma-cyclodextrin, GLYCEROL
著者Feng, L., Nosrati, M., Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
1XZY
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SOLUTION STRUCTURE OF THE P30-TRANS FORM OF ALPHA HEMOGLOBIN STABILIZING PROTEIN (AHSP)
分子名称:Alpha-hemoglobin stabilizing protein
著者Gell, D.A., Feng, L., Zhou, S., Kong, Y., Lee, C., Weiss, M.J., Shi, Y., Mackay, J.P.
登録日2004-11-12
公開日2004-12-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin
Cell(Cambridge,Mass.), 119, 2004
4DMN
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HIV-1 INTEGRASE CATALYTICAL CORE DOMAIN
分子名称:HIV-1 Integrase, ARSENIC, SULFATE ION, ...
著者Feng, L., Kvaratskhelia, M.
登録日2012-02-08
公開日2012-03-21
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
J.Biol.Chem., 287, 2012
4O0J
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN COMPLEXED WITH ALLOSTERIC INHIBITOR (2S)-TERT-BUTOXY[4-(4-CHLOROPHENYL)-6-(3,4-DIMETHYLPHENYL)-2,5-DIMETHYLPYRIDIN-3-YL]ETHANOIC ACID
分子名称:Integrase, (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid, SULFATE ION
著者Feng, L., Kvaratskhelia, M.
登録日2013-12-13
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4O55
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN COMPLEXED WITH ALLOSTERIC INHIBITOR (2S)-TERT-BUTOXY[6-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)-2,5-DIMETHYL-4-PHENYLPYRIDIN-3-YL]ETHANOIC ACID
分子名称:Integrase, (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, SULFATE ION
著者Feng, L., Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4O5B
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN COMPLEXED WITH ALLOSTERIC INHIBITOR (2S)-TERT-BUTOXY[6-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)-2,5-DIMETHYL-4-PHENYLPYRIDIN-3-YL]ETHANOIC ACID
分子名称:Integrase, (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, SULFATE ION
著者Feng, L., Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
3B4R
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SITE-2 PROTEASE FROM METHANOCALDOCOCCUS JANNASCHII
分子名称:Putative zinc metalloprotease MJ0392, ZINC ION
著者Jeffrey, P.D., Feng, L., Yan, H., Wu, Z., Yan, N., Wang, Z., Shi, Y.
登録日2007-10-24
公開日2008-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a site-2 protease family intramembrane metalloprotease.
Science, 318, 2007