Author results

1QLP
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2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS
Descriptor:ALPHA-1-ANTITRYPSIN
Authors:Elliott, P.R., Pei, X.Y., Dafforn, T., Read, R.J., Carrell, R.W., Lomas, D.A.
Deposit date:1999-09-10
Release date:1999-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Topography of a 2.0 A Structure of Alpha1-Antitrypsin Reveals Targets for Rational Drug Design to Prevent Conformational Disease.
Protein Sci., 9, 2000
3IVF
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CRYSTAL STRUCTURE OF THE TALIN HEAD FERM DOMAIN
Descriptor:Talin-1
Authors:Elliott, P.R., Goult, B.T., Bate, N., Grossmann, J.G., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
3PV1
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CRYSTAL STRUCTURE OF THE USP15 DUSP-UBL DOMAINS
Descriptor:Ubiquitin carboxyl-terminal hydrolase 15, ACETATE ION
Authors:Elliott, P.R., Urbe, S., Clague, M.J., Barsukov, I.L.
Deposit date:2010-12-06
Release date:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Febs Lett., 585, 2011
4A3O
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CRYSTAL STRUCTURE OF THE USP15 DUSP-UBL MONOMER
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15, GLYCEROL
Authors:Elliott, P.R., Liu, H., Pastok, M.W., Grossmann, G.J., Rigden, D.J., Clague, M.J., Urbe, S., Barsukov, I.L.
Deposit date:2011-10-03
Release date:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
4A3P
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STRUCTURE OF USP15 DUSP-UBL DELETION MUTANT
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15, ACETATE ION, IODIDE ION
Authors:Elliott, P.R., Liu, H., Pastok, M.W., Grossmann, G.J., Rigden, D.J., Clague, M.J., Urbe, S., Barsukov, I.L.
Deposit date:2011-10-03
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
4OYJ
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STRUCTURE OF THE APO HOIP PUB DOMAIN
Descriptor:E3 ubiquitin-protein ligase RNF31, SULFATE ION
Authors:Elliott, P.R., Komander, D.
Deposit date:2014-02-12
Release date:2014-05-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
4OYK
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STRUCTURE OF HOIP PUB DOMAIN BOUND TO OTULIN PIM
Descriptor:E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin, CHLORIDE ION
Authors:Elliott, P.R., Komander, D.
Deposit date:2014-02-12
Release date:2014-05-21
Method:X-RAY DIFFRACTION (2.0001 Å)
Cite:Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
5LJM
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STRUCTURE OF SPATA2 PUB DOMAIN
Descriptor:Spermatogenesis-associated protein 2, GLYCEROL
Authors:Elliott, P.R., Komander, D.
Deposit date:2016-07-18
Release date:2016-08-24
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.454 Å)
Cite:SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
5LJN
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STRUCTURE OF THE HOIP PUB DOMAIN BOUND TO SPATA2 PIM PEPTIDE
Descriptor:E3 ubiquitin-protein ligase RNF31, Spermatogenesis-associated protein 2, SULFATE ION, ...
Authors:Elliott, P.R., Komander, D.
Deposit date:2016-07-18
Release date:2016-08-24
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
1PSI
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INTACT RECOMBINED ALPHA1-ANTITRYPSIN MUTANT PHE 51 TO LEU
Descriptor:ALPHA=1=-ANTITRYPSIN
Authors:Abrahams, J.P., Elliott, P.R., Lomas, D.A., Carrell, R.W.
Deposit date:1996-06-11
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.
Nat.Struct.Biol., 3, 1996
2LNK
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SOLUTION STRUCTURE OF CA-BOUND S100A4 IN COMPLEX WITH NON-MUSCLE MYOSIN IIA
Descriptor:Myosin heavy chain, non-muscle IIa, Protein S100-A4
Authors:Barsukov, I.L., Elliott, P.R.
Deposit date:2011-12-30
Release date:2012-04-25
Method:SOLUTION NMR
Cite:Asymmetric Mode of Ca(2+)-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling.
Structure, 20, 2012
5OE7
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STRUCTURE OF OTULIN BOUND TO THE MET1-LINKED DIUBIQUITIN ACTIVITY PROBE
Descriptor:Ubiquitin thioesterase otulin, Polyubiquitin-C
Authors:Elliott, P.R., Komander, D.
Deposit date:2017-07-07
Release date:2017-09-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
2KC1
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NMR STRUCTURE OF THE F0 DOMAIN (RESIDUES 0-85) OF THE TALIN FERM DOMAIN
Descriptor:MKIAA1027 protein
Authors:Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KC2
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NMR STRUCTURE OF THE F1 DOMAIN (RESIDUES 86-202) OF THE TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchely, D.R., Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KMA
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NMR STRUCTURE OF THE F0F1 DOUBLE DOMAIN (RESIDUES 1-202) OF THE TALIN FERM DOMAIN
Descriptor:Talin 1
Authors:Goult, B.T., Elliott, P.R., Bate, N., Roberts, G.C., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-07-25
Release date:2010-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 2010
3ZDL
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VINCULIN HEAD (1-258) IN COMPLEX WITH A RIAM FRAGMENT
Descriptor:VINCULIN, AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN
Authors:Zacharchenko, T., Elliott, P.R., Goult, B.T., Bate, N., Critchely, D.R., Barsukov, I.L.
Deposit date:2012-11-28
Release date:2013-02-13
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
3ZNV
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CRYSTAL STRUCTURE OF THE OTU DOMAIN OF OTULIN AT 1.3 ANGSTROMS.
Descriptor:PROTEIN FAM105B, GLYCEROL, CALCIUM ION, ...
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNX
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CRYSTAL STRUCTURE OF THE OTU DOMAIN OF OTULIN D336A MUTANT
Descriptor:PROTEIN FAM105B, CALCIUM ION, CHLORIDE ION, ...
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNZ
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CRYSTAL STRUCTURE OF OTULIN OTU DOMAIN (C129A) IN COMPLEX WITH MET1- DI UBIQUITIN
Descriptor:PROTEIN FAM105B, POLYUBIQUITIN-C, SULFATE ION
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
4BOP
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STRUCTURE OF OTUD1 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 1, PHOSPHATE ION
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOQ
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STRUCTURE OF OTUD2 OTU DOMAIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOS
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH UBIQUITIN K11-LINKED PEPTIDE
Descriptor:UBIQUITIN THIOESTERASE OTU1, POLYUBIQUITIN-C, OTUD2, ...
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOU
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STRUCTURE OF OTUD3 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 3
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOZ
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH K11-LINKED DI UBIQUITIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
5AF4
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STRUCTURE OF LYS33-LINKED DIUB
Descriptor:UBIQUITIN, GLYCEROL, SULFATE ION
Authors:Michel, M.A., Elliott, P.R., Swatek, K.N., Simicek, M., Pruneda, J.N., Wagstaff, J.L., Freund, S.M.V., Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
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