Author results

2PNT
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASP (GRP1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE OF THE METABOTROPIC GLUTAMATE RECEPTOR TYPE 1
分子名称:General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION
著者Elkins, J., Papagrigoriou, E., Cooper, C., Gileadi, C., Uppenberg, J., Bray, J., von Delft, F., Pike, A.C.W., Ugochukwu, E., Umeano, C., Gileadi, O., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-04-25
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1.
To be Published
2VD5
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STRUCTURE OF HUMAN MYOTONIC DYSTROPHY PROTEIN KINASE IN COMPLEX WITH THE BISINDOYLMALEIDE INHIBITOR BIM VIII
分子名称:DMPK PROTEIN, 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE
著者Pike, A.C.W., Amos, A., Elkins, J., Bullock, A., Guo, K., Fedorov, O., Bunkoczi, G., Filippakopoulos, P., Pilka, E.S., Ugochukwu, E., Umeano, C., Niesen, F., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C.H., von Delft, F., Knapp, S.
登録日2007-09-30
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Dystrophia Myotonica Protein Kinase.
Protein Sci., 18, 2009
2CLS
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THE CRYSTAL STRUCTURE OF THE HUMAN RND1 GTPASE IN THE ACTIVE GTP BOUND STATE
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHO6, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Yang, X., Colebrook, S., Gileadi, O., Sobott, F., Bray, J., Wen Hwa, L., Marsden, B., Zhao, Y., Schoch, G., Elkins, J., Debreczeni, J.E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-04-28
公開日2006-05-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The Crystal Structure of the Human Rnd1 Gtpase in the Active GTP Bound State
To be Published
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
分子名称:regulator of G-protein signalling 3 isoform 1, SULFATE ION
著者Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2005-11-28
公開日2005-12-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
分子名称:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
著者Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2005-12-15
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2GF0
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THE CRYSTAL STRUCTURE OF THE HUMAN DIRAS1 GTPASE IN THE INACTIVE GDP BOUND STATE
分子名称:GTP-binding protein Di-Ras1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Papagrigoriou, E., Yang, X., Schoch, G., Elkins, J., Gileadi, O., Salah, E., Bray, J., Wen-Hwa, L., Fedorov, O., Niesen, F.E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-03-21
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
To be Published
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-08-14
公開日2006-09-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2JIK
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CRYSTAL STRUCTURE OF PDZ DOMAIN OF SYNAPTOJANIN-2 BINDING PROTEIN
分子名称:SYNAPTOJANIN-2 BINDING PROTEIN
著者Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2007-06-28
公開日2007-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
2JIL
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CRYSTAL STRUCTURE OF 2ND PDZ DOMAIN OF GLUTAMATE RECEPTOR INTERACTING PROTEIN-1 (GRIP1)
分子名称:GLUTAMATE RECEPTOR INTERACTING PROTEIN-1, THIOCYANATE ION, 1,2-ETHANEDIOL
著者Tickle, J., Elkins, J., Pike, A.C.W., Cooper, C., Salah, E., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2007-06-28
公開日2007-07-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of 2Nd Pdz Domain of Glutamate Receptor Interacting Protein-1 (Grip1)
To be Published
2JIN
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CRYSTAL STRUCTURE OF PDZ DOMAIN OF SYNAPTOJANIN-2 BINDING PROTEIN
分子名称:SYNAPTOJANIN-2 BINDING PROTEIN, SODIUM ION, SULFATE ION
著者Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2007-06-28
公開日2007-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
2ODB
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THE CRYSTAL STRUCTURE OF HUMAN CDC42 IN COMPLEX WITH THE CRIB DOMAIN OF HUMAN P21-ACTIVATED KINASE 6 (PAK6)
分子名称:Human Cell Division Cycle 42 (CDC42), Serine/threonine-protein kinase PAK 6, CHLORIDE ION, ...
著者Ugochukwu, E., Yang, X., Elkins, J., Soundararajan, M., Pike, A.C.W., Eswaran, J., Burgess, N., Debreczeni, J.E., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Gileadi, O., von Delft, F., Knapp, S., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-12-22
公開日2007-01-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
To be Published
2OVJ
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC GTPASE ACTIVATING PROTEIN 1 (RACGAP1) MGCRACGAP.
分子名称:Rac GTPase-activating protein 1, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
著者Shrestha, L., Papagrigoriou, E., Soundararajan, M., Elkins, J., Johansson, C., von Delft, F., Pike, A.C.W., Burgess, N., Turnbull, A., Debreczeni, J., Gorrec, F., Umeano, C., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-14
公開日2007-02-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
分子名称:Ezrin-radixin-moesin-binding phosphoprotein 50
著者Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-26
公開日2007-03-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2PA1
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STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM2 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN
分子名称:PDZ and LIM domain protein 2, CHLORIDE ION
著者Uppenberg, J., Shrestha, L., Elkins, J., Burgess-Brown, N., Salah, E., Bunkoczi, G., Papagrigoriou, E., Pike, A.C.W., Turnbull, A.P., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-03-27
公開日2007-05-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin.
To be Published
2PKT
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CRYSTAL STRUCTURE OF THE HUMAN CLP-36 (PDLIM1) BOUND TO THE C-TERMINAL PEPTIDE OF HUMAN ALPHA-ACTININ-1
分子名称:PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ...
著者Uppenberg, J., Gileadi, C., Elkins, J., Bray, J., Burgess-Brown, N., Salah, E., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-04-18
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1.
To be Published
2Q3G
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STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM7 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN
分子名称:PDZ and LIM domain protein 7, 1,2-ETHANEDIOL, CHLORIDE ION
著者Gileadi, C., Papagrigoriou, E., Elkins, J., Burgess-Brown, N., Salah, E., Gileadi, O., Umeano, C., Bunkoczi, G., von Delft, F., Uppenberg, J., Pike, A.C.W., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
To be Published
2Q3H
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THE CRYSTAL STRUCTURE OF RHOUA IN THE GDP-BOUND STATE.
分子名称:Ras homolog gene family, member U, MAGNESIUM ION, ...
著者Gileadi, C., Yang, X., Papagrigoriou, E., Elkins, J., Zhao, Y., Bray, J., Gileadi, O., Umeano, C., Ugochukwu, E., Uppenberg, J., Bunkoczi, G., von Delft, F., Pike, A.C.W., Phillips, C., Savitsky, P., Fedorov, O., Edwards, A., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The crystal structure of RhouA in the GDP-bound state.
To be Published
2RF0
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CRYSTAL STRUCTURE OF HUMAN MIXED LINEAGE KINASE MAP3K10 SH3 DOMAIN
分子名称:Mitogen-activated protein kinase kinase kinase 10, 1,2-ETHANEDIOL
著者Ugochukwu, E., Eswaran, J., Elkins, J., Keates, T., Pike, A.C.W., Berridge, G., Savitsky, P., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-10-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of human Mixed lineage kinase MAP3K10 SH3 domain.
To be Published
2V90
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CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF INTESTINE- AND KIDNEY- ENRICHED PDZ DOMAIN IKEPP (PDZD3)
分子名称:PDZ DOMAIN-CONTAINING PROTEIN 3, SULFATE ION
著者Uppenberg, J., Gileadi, C., Phillips, C., Elkins, J., Bunkoczi, G., Cooper, C., Pike, A.C.W., Salah, E., Ugochukwu, E., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Doyle, D.A.
登録日2007-08-16
公開日2007-08-28
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the 3Rd Pdz Domain of Intestine- and Kidney-Enriched Pdz Domain Ikepp (Pdzd3)
To be Published
2VSW
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THE STRUCTURE OF THE RHODANESE DOMAIN OF THE HUMAN DUAL SPECIFICITY PHOSPHATASE 16
分子名称:DUAL SPECIFICITY PROTEIN PHOSPHATASE 16
著者Murray, J.W., Barr, A., Pike, A.C.W., Elkins, J., Phillips, C., Wang, J., Savitsky, P., Roos, A., Bishop, S., Wickstroem, M., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Burgess-Brown, N., Pantic, N., Bray, J., von Delft, F., Gileadi, O., Knapp, S.
登録日2008-04-30
公開日2008-07-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structure of the Rhodanese Domain of the Human Dual Specifity Phosphatase 16
To be Published
2Y7B
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF HUMAN ACTIN-BINDING PROTEIN ANILLIN ANLN
分子名称:ACTIN-BINDING PROTEIN ANILLIN, 1,2-ETHANEDIOL
著者Vollmar, M., Wang, J., Krojer, T., Elkins, J., Filippakopoulos, P., Ugochukwu, E., Cocking, R., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.
登録日2011-01-31
公開日2011-03-30
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Ph Domain of Human Actin-Binding Protein Anillin Anln
To be Published
3BYI
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CRYSTAL STRUCTURE OF HUMAN RHO GTPASE ACTIVATING PROTEIN 15 (ARHGAP15)
分子名称:Rho GTPase activating protein 15
著者Shrestha, L., Tickle, J., Elkins, J., Burgess-Brown, N., Johansson, C., Papagrigoriou, E., Kavanagh, K., Pike, A.C.W., Ugochukwu, E., Uppenberg, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Doyle, D., Structural Genomics Consortium (SGC)
登録日2008-01-16
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Human Rho GTPase Activating Protein 15 (ARHGAP15).
To be Published
3GP0
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CRYSTAL STRUCTURE OF HUMAN MITOGEN ACTIVATED PROTEIN KINASE 11 (P38 BETA) IN COMPLEX WITH NILOTINIB
分子名称:Mitogen-activated protein kinase 11, Nilotinib, 1,2-ETHANEDIOL, ...
著者Filippakopoulos, P., Barr, A., Fedorov, O., Keates, T., Soundararajan, M., Elkins, J., Salah, E., Burgess-Brown, N., Ugochukwu, E., Pike, A.C.W., Muniz, J., Roos, A., Chaikuad, A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-03-20
公開日2009-04-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib
To be Published
3KHF
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THE CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN MICROTUBULE ASSOCIATED SERINE/THREONINE KINASE 3 (MAST3)
分子名称:Microtubule-associated serine/threonine-protein kinase 3, 1,2-ETHANEDIOL, CHLORIDE ION
著者Roos, A., Elkins, J., Savitsky, P., Wang, J., Ugochukwu, E., Murray, J., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-10-30
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The crystal structure of the PDZ domain of human Microtubule Associated Serine/Threonine Kinase 3 (MAST3)
To be Published
5QGG
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PANDDA ANALYSIS GROUP DEPOSITION OF MODELS WITH MODELLED EVENTS (E.G. BOUND LIGANDS) -- CRYSTAL STRUCTURE OF NUDT7 IN COMPLEX WITH FMOPL000693A
分子名称:Peroxisomal coenzyme A diphosphatase NUDT7, ACETATE ION, DIMETHYL SULFOXIDE, ...
著者Krojer, T., Talon, R., Fairhead, M., Diaz Saez, L., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Ruda, G.F., Szommer, T., Srikannathasan, V., Elkins, J., Spencer, J., London, N., Nelson, A., Brennan, P.E., Huber, K., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
登録日2018-05-15
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献PanDDA analysis group deposition of models with modelled events (e.g. bound ligands)
To Be Published