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1QZ8
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS NSP9
Descriptor:polyprotein 1ab, SULFATE ION
Authors:Egloff, M.P., Ferron, F., Campanacci, V., Longhi, S., Rancurel, C., Dutartre, H., Snijder, E.J., Gorbalenya, A.E., Cambillau, C., Canard, B.
Deposit date:2003-09-16
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.
Proc.Natl.Acad.Sci.USA, 101, 2004
1L9K
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DENGUE METHYLTRANSFERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Egloff, M.P., Benarroch, D., Selisko, B., Romette, J.L., Canard, B.
Deposit date:2002-03-25
Release date:2003-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
2FAV
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CRYSTAL STRUCTURE OF SARS MACRO DOMAIN IN COMPLEX WITH ADP-RIBOSE AT 1.8 A RESOLUTION
Descriptor:Replicase polyprotein 1ab (pp1ab) (ORF1AB), ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2005-12-08
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.
J.Virol., 80, 2006
2P1D
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GTP AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Benarooch, D., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-05
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
EMBO J., 21, 2002
2P3L
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3O
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3Q
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPG AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, DIGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P40
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG
Descriptor:type II methyltransferase, SULFATE ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P41
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG2'OME AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-GUANOSINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2HCN
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), CALCIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCS
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CRYSTAL STRUCTURE OF RNA DEPENDANT RNA POLYMERASE DOMAIN OF WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-18
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HFZ
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase(NS5), MAGNESIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-26
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
1R6A
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STRUCTURE OF THE DENGUE VIRUS 2'O METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE AND RIBAVIRIN 5' TRIPHOSPHATE
Descriptor:Genome polyprotein, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Benarroch, D., Egloff, M.P., Mulard, L., Romette, J.L., Canard, B.
Deposit date:2003-10-15
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.
J.Biol.Chem., 279, 2004
1VIW
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TENEBRIO MOLITOR ALPHA-AMYLASE-INHIBITOR COMPLEX
Descriptor:ALPHA-AMYLASE, ALPHA-AMYLASE-INHIBITOR, CHLORIDE ION, ...
Authors:Nahoum, V., Egloff, M.P., Payan, F.
Deposit date:1998-07-21
Release date:1999-07-22
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:A plant-seed inhibitor of two classes of alpha-amylases: X-ray analysis of Tenebrio molitor larvae alpha-amylase in complex with the bean Phaseolus vulgaris inhibitor.
Acta Crystallogr.,Sect.D, 55, 1999
2H85
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CRYSTAL STRUCTURE OF NSP 15 FROM SARS
Descriptor:Putative orf1ab polyprotein
Authors:Ricagno, S., Egloff, M.P., Ulferts, R., Coutard, B., Nurizzo, D., Campanacci, V., Cambillau, C., Ziebuhr, J., Canard, B.
Deposit date:2006-06-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2J7U
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN
Descriptor:RNA DEPENDENT RNA POLYMERASE, ZINC ION, MAGNESIUM ION, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7W
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN COMPLEXED WITH 3' DGTP
Descriptor:POLYPROTEIN, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
1LPB
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THE 2.46 ANGSTROMS RESOLUTION STRUCTURE OF THE PANCREATIC LIPASE COLIPASE COMPLEX INHIBITED BY A C11 ALKYL PHOSPHONATE
Descriptor:COLIPASE, LIPASE, B-OCTYLGLUCOSIDE, ...
Authors:Egloff, M.-P., Van Tilbeurgh, H., Cambillau, C.
Deposit date:1994-08-19
Release date:1994-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate.
Biochemistry, 34, 1995
1LPA
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INTERFACIAL ACTIVATION OF THE LIPASE-PROCOLIPASE COMPLEX BY MIXED MICELLES REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:COLIPASE, LIPASE, B-NONYLGLUCOSIDE, ...
Authors:Van Tilbeurgh, H., Egloff, M.-P., Cambillau, C.
Deposit date:1994-08-19
Release date:1994-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography.
Nature, 362, 1993
1HLG
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CRYSTAL STRUCTURE OF HUMAN GASTRIC LIPASE
Descriptor:LIPASE, GASTRIC, N-ACETYL-D-GLUCOSAMINE
Authors:Roussel, A., Canaan, S., Verger, R., Cambillau, C.
Deposit date:1999-03-12
Release date:2000-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest.
J.Biol.Chem., 274, 1999
2CUT
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CUTINASE, A LIPOLYTIC ENZYME WITH A PREFORMED OXYANION HOLE
Descriptor:CUTINASE, DIETHYL PHOSPHONATE
Authors:Martinez, C., Cambillau, C.
Deposit date:1994-06-03
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cutinase, a lipolytic enzyme with a preformed oxyanion hole.
Biochemistry, 33, 1994
1CEX
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STRUCTURE OF CUTINASE
Descriptor:CUTINASE
Authors:Longhi, S., Czjzek, M., Lamzin, V., Nicolas, A., Cambillau, C.
Deposit date:1997-02-18
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution (1.0 A) crystal structure of Fusarium solani cutinase: stereochemical analysis.
J.Mol.Biol., 268, 1997
1CUA
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CUTINASE, N172K MUTANT
Descriptor:CUTINASE
Authors:Longhi, S., Cambillau, C.
Deposit date:1995-11-16
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants.
Proteins, 26, 1996
1CUB
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CUTINASE, N172K, R196D MUTANT, MONOCLINIC CRYSTAL FORM
Descriptor:CUTINASE
Authors:Longhi, S., Cambillau, C.
Deposit date:1995-11-16
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants.
Proteins, 26, 1996
1CUC
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CUTINASE, N172K, R196D MUTANT, ORTHORHOMBIC CRYSTAL FORM
Descriptor:CUTINASE
Authors:Longhi, S., Cambillau, C.
Deposit date:1995-11-16
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants.
Proteins, 26, 1996
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