Author results

2XFU
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HUMAN MONOAMINE OXIDASE B WITH TRANYLCYPROMINE
Descriptor:Amine oxidase [flavin-containing] B, [[(2R,3S,4S)-5-[(4AS)-7,8-DIMETHYL-2,4-DIOXO-4A,5-DIHYDROBENZO[G]PTERIDIN-10-YL]-2,3,4-TRIHYDROXY-PENTOXY]-HYDROXY-PHOSPHORYL] [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL HYDROGEN PHOSPHATE, 3-PHENYLPROPANAL
Authors:Binda, C., Li, M., Hubalek, F., Restelli, N., Edmondson, D.E., Mattevi, A.
Deposit date:2010-05-26
Release date:2010-06-09
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Potentiation of ligand binding through cooperative effects in monoamine oxidase B.
J. Biol. Chem., 285, 2010
1GOS
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HUMAN MONOAMINE OXIDASE B
Descriptor:MONOAMINE OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, N-[(E)-METHYL](PHENYL)-N-[(E)-2-PROPENYLIDENE]METHANAMINIUM
Authors:Binda, C., Newton-Vinson, P., Hubalek, F., Edmondson, D.E., Mattevi, A.
Deposit date:2001-10-26
Release date:2001-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Human Monoamine Oxidase B, a Drug Target for the Treatment of Neurological Disorders
Nat.Struct.Biol., 9, 2001
1OJ9
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH 1,4-DIPHENYL-2-BUTENE
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, 1,4-DIPHENYL-2-BUTENE
Authors:Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2003-07-08
Release date:2003-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Proc.Natl.Acad.Sci.USA, 100, 2003
1OJA
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH ISATIN
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, ISATIN
Authors:Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2003-07-08
Release date:2003-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Insights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Proc.Natl.Acad.Sci.USA, 100, 2003
1OJC
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE
Authors:Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2003-07-08
Release date:2003-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Proc.Natl.Acad.Sci.USA, 100, 2003
1OJD
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH LAURYLDIMETHYLAMINE-N-OXIDE (LDAO)
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, LAURYL DIMETHYLAMINE-N-OXIDE
Authors:Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2003-07-08
Release date:2003-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Insights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Proc.Natl.Acad.Sci.USA, 100, 2003
1S2Q
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CRYSTAL STRUCTURE OF MAOB IN COMPLEX WITH N-PROPARGYL-1(R)-AMINOINDAN (RASAGILINE)
Descriptor:Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2004-01-09
Release date:2004-03-30
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class.
J.Med.Chem., 47, 2004
1S2Y
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CRYSTAL STRUCTURE OF MAOB IN COMPLEX WITH N-PROPARGYL-1(S)-AMINOINDAN
Descriptor:Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2004-01-12
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class.
J.Med.Chem., 47, 2004
1S3B
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CRYSTAL STRUCTURE OF MAOB IN COMPLEX WITH N-METHYL-N-PROPARGYL-1(R)-AMINOINDAN
Descriptor:Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, N-[(1S)-2,3-DIHYDRO-1H-INDEN-1-YL]-N-METHYL-N-PROP-2-YNYLAMINE
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2004-01-13
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class.
J.Med.Chem., 47, 2004
1S3E
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CRYSTAL STRUCTURE OF MAOB IN COMPLEX WITH 6-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN
Descriptor:Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, (3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2004-01-13
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class.
J.Med.Chem., 47, 2004
2BK3
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH FARNESOL
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
Authors:Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2005-02-10
Release date:2005-02-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
J. Biol. Chem., 280, 2005
2BK4
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HUMAN MONOAMINE OXIDASE B: I199F MUTANT IN COMPLEX WITH RASAGILINE
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine
Authors:Binda, C., Edmondson, D.E., Mattevi, A., Hubalek, F., Khalil, A., Li, M., Castagnoli, N.
Deposit date:2005-02-10
Release date:2005-02-14
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors
J.Biol.Chem., 280, 2005
2BK5
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HUMAN MONOAMINE OXIDASE B: I199F MUTANT IN COMPLEX WITH ISATIN
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, ISATIN
Authors:Binda, C., Edmondson, D.E., Mattevi, A., Hubalek, F., Khalil, A., Li, M., Castagnoli, N.
Deposit date:2005-02-10
Release date:2005-02-14
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors.
J.Biol.Chem., 280, 2005
2BXR
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HUMAN MONOAMINE OXIDASE A IN COMPLEX WITH CLORGYLINE, CRYSTAL FORM A
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE
Authors:De Colibus, L., Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-27
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
2BXS
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HUMAN MONOAMINE OXIDASE A IN COMPLEX WITH CLORGYLINE, CRYSTAL FORM B
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE
Authors:De Colibus, L., Binda, C., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-27
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
2BYB
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH DEPRENYL
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, DEPRENYL
Authors:Binda, C., De Colibus, L., Edmondson, D.E., Mattevi, A.
Deposit date:2005-07-29
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Proc.Natl.Acad.Sci.USA, 102, 2005
2C64
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MAO INHIBITION BY RASAGILINE ANALOGUES
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, (1R)-6-HYDROXY-N-METHYL-N-[(1Z)-PROP-2-EN-1-YLIDENE]INDAN-1-AMINIUM
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2005-11-07
Release date:2006-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis.
J.Med.Chem., 48, 2005
2C65
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MAO INHIBITION BY RASAGILINE ANALOGUES
Descriptor:AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, (1R)-4-({[ETHYL(METHYL)AMINO]CARBONYL}OXY)-N-METHYL-N-[(1E)-PROP-2-EN-1-YLIDENE]INDAN-1-AMINIUM
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2005-11-07
Release date:2006-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis.
J.Med.Chem., 48, 2005
2C66
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MAO INHIBITION BY RASAGILINE ANALOGUES
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2005-11-07
Release date:2006-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis.
J.Med.Chem., 48, 2005
2C67
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MAO INHIBITION BY RASAGILINE ANALOGUES
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-METHYL-1(R)-AMINOINDAN
Authors:Binda, C., Hubalek, F., Li, M., Herzig, Y., Sterling, J., Edmondson, D.E., Mattevi, A.
Deposit date:2005-11-07
Release date:2006-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis.
J.Med.Chem., 48, 2005
2C70
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FUNCTIONAL ROLE OF THE AROMATIC CAGE IN HUMAN MONOAMINE OXIDASE B: STRUCTURES AND CATALYTIC PROPERTIES OF TYR435 MUTANT PROTEINS
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, P-NITRO-BENZYLAMINE
Authors:Li, M., Binda, C., Mattevi, A., Edmondson, D.E.
Deposit date:2005-11-17
Release date:2006-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45, 2006
2C72
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FUNCTIONAL ROLE OF THE AROMATIC CAGE IN HUMAN MONOAMINE OXIDASE B: STRUCTURES AND CATALYTIC PROPERTIES OF TYR435 MUTANT PROTEINS
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN
Authors:Li, M., Binda, C., Mattevi, A., Edmondson, D.E.
Deposit date:2005-11-17
Release date:2006-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45, 2006
2C73
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FUNCTIONAL ROLE OF THE AROMATIC CAGE IN HUMAN MONOAMINE OXIDASE B: STRUCTURES AND CATALYTIC PROPERTIES OF TYR435 MUTANT PROTEINS
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN
Authors:Li, M., Binda, C., Mattevi, A., Edmondson, D.E.
Deposit date:2005-11-17
Release date:2006-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45, 2006
2C75
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FUNCTIONAL ROLE OF THE AROMATIC CAGE IN HUMAN MONOAMINE OXIDASE B: STRUCTURES AND CATALYTIC PROPERTIES OF TYR435 MUTANT PROTEINS
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN
Authors:Li, M., Binda, C., Mattevi, A., Edmondson, D.E.
Deposit date:2005-11-17
Release date:2006-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45, 2006
2C76
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FUNCTIONAL ROLE OF THE AROMATIC CAGE IN HUMAN MONOAMINE OXIDASE B: STRUCTURES AND CATALYTIC PROPERTIES OF TYR435 MUTANT PROTEINS
Descriptor:AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN
Authors:Li, M., Binda, C., Mattevi, A., Edmondson, D.E.
Deposit date:2005-11-17
Release date:2006-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45, 2006
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