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1B9S
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NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE
Descriptor:PROTEIN (NEURAMINIDASE), N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Finley, J.B., Atigadda, V.R., Duarte, F., Zhao, J.J., Brouillette, W.J., Air, G.M., Luo, M.
Deposit date:1999-02-15
Release date:1999-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
J.Mol.Biol., 293, 1999
1B9T
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NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE
Descriptor:PROTEIN (NEURAMINIDASE), N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Finley, J.B., Atigadda, V.R., Duarte, F., Zhao, J.J., Brouillette, W.J., Air, G.M., Luo, M.
Deposit date:1999-02-15
Release date:1999-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
J.Mol.Biol., 293, 1999
1B9V
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NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN TEH ACTIVE SITE
Descriptor:PROTEIN (NEURAMINIDASE), N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Finley, J.B., Atigadda, V.R., Duarte, F., Zahao, J.J., Brouillette, W.J., Air, G.M., Luo, M.
Deposit date:1999-02-15
Release date:1999-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
J.Mol.Biol., 293, 1999
4CXK
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G9 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:ARYLSULFATASE, CALCIUM ION, SULFATE ION, ...
Authors:Miton, C.M., Jonas, S., Mohammed, M.F., Fischer, G., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2014-04-07
Release date:2015-04-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CXS
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G4 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA, IN COMPLEX WITH PHENYLPHOSPHONIC ACID
Descriptor:ARYLSULFATASE, CALCIUM ION, SULFATE ION, ...
Authors:Miton, C.M., Jonas, S., Mohammed, M.F., Fischer, G., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2014-04-08
Release date:2015-05-13
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CXU
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G4 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA, IN COMPLEX WITH 3-BR-PHENOLPHENYLPHOSPHONATE
Descriptor:ARYLSULFATASE, CALCIUM ION, 3-bromophenyl hydrogen (S)-phenylphosphonate
Authors:Miton, C.M., Jonas, S., Mohammed, M.F., Fischer, G., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2014-04-08
Release date:2015-04-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CYR
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G4 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:ARYLSULFATASE, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
Authors:Miton, C.M., Jonas, S., Mohammed, M.F., Fischer, G., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2014-04-14
Release date:2015-04-29
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CYS
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G6 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA, IN COMPLEX WITH PHENYLPHOSPHONIC ACID
Descriptor:ARYLSULFATASE, CALCIUM ION, phenylphosphonic acid, ...
Authors:Miton, C.M., Jonas, S., Mohammed, M.F., Fischer, G., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2014-04-14
Release date:2015-04-29
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5AJ9
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G7 MUTANT OF PAS, ARYLSULFATASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:ARYLSULFATASE, CALCIUM ION, SULFATE ION, ...
Authors:Miton, C.M., Fischer, G., Jonas, S., Mohammed, M.F., Loo, B.v., Kintses, B., Hyvonen, M., Tokuriki, N., Hollfelder, F.
Deposit date:2015-02-20
Release date:2016-03-16
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4Y9S
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STRUCTURE OF AN H300N MUTANT OF POTATO EPOXIDE HYDROLASE, STEH1
Descriptor:Epoxide hydrolase
Authors:Naworyta, A., Mowbray, S.L., Widersten, M.
Deposit date:2015-02-17
Release date:2015-09-16
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.
ACS Catal, 5, 2015
5G2H
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S. ENTERICA HISA WITH MUTATION L169R
Descriptor:SULFATE ION, GLYCEROL, SODIUM ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2I
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S. ENTERICA HISA MUTANT DUP13-15(VVR)
Descriptor:PHOSPHATE ION, SODIUM ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4E
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S. ENTERICA HISA MUTANT D10G, DUP13-15, Q24L, G102A, V106L
Descriptor:SULFATE ION, SODIUM ION, ACETIC ACID, ...
Authors:Soderholm, A., Guo, X., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-12
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4W
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S. ENTERICA HISA MUTANT D7N, D10G, DUP13-15 (VVR) WITH SUBSTRATE PROFAR
Descriptor:HISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-17
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017