5G4W

S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR

Summary for 5G4W

Related5G4E
DescriptorHISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL, ... (4 entities in total)
Functional Keywordsisomerase, hisa, protein evolution, iad model, trpf
Biological sourceSALMONELLA ENTERICA
Cellular locationCytoplasm  V7IJE3
Total number of polymer chains1
Total molecular weight28189.88
Authors
Guo, X.,Soderholm, A.,Newton, M.,Nasvall, J.,Duarte, F.,Andersson, D.,Patrick, W.,Selmer, M. (deposition date: 2016-05-17, release date: 2017-04-19, Last modification date: 2017-05-10)
Primary citation
Newton, M.S.,Guo, X.,Soderholm, A.,Nasvall, J.,Lundstrom, P.,Andersson, D.I.,Selmer, M.,Patrick, W.M.
Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114:4727-4732, 2017
PubMed: 28416687 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1618552114
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2674004.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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