5G4W
S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GUO A 1245 |
| Chain | Residue |
| A | ASN7 |
| A | ALA127 |
| A | ASP129 |
| A | LEU169 |
| A | SER202 |
| A | ILE223 |
| A | GLY225 |
| A | ARG226 |
| A | HOH2015 |
| A | HOH2021 |
| A | HOH2022 |
| A | ARG15 |
| A | HOH2061 |
| A | HOH2062 |
| A | VAL15 |
| A | VAL49 |
| A | LEU51 |
| A | GLY80 |
| A | GLY81 |
| A | GLY102 |
| A | SER103 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1246 |
| Chain | Residue |
| A | ASP37 |
| A | ALA40 |
| A | LYS232 |
| A | GLU237 |
| A | HOH2063 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1247 |
| Chain | Residue |
| A | ASP110 |
| A | LYS113 |
| A | PHE119 |
| A | GLN122 |
