5G4W

S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GUO A 1245

Chain	Residue
A	ASN7
A	ALA127
A	ASP129
A	LEU169
A	SER202
A	ILE223
A	GLY225
A	ARG226
A	HOH2015
A	HOH2021
A	HOH2022
A	ARG15
A	HOH2061
A	HOH2062
A	VAL15
A	VAL49
A	LEU51
A	GLY80
A	GLY81
A	GLY102
A	SER103

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1246

Chain	Residue
A	ASP37
A	ALA40
A	LYS232
A	GLU237
A	HOH2063

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1247

Chain	Residue
A	ASP110
A	LYS113
A	PHE119
A	GLN122

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