Author results

1BMT
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HOW A PROTEIN BINDS B12: A 3.O ANGSTROM X-RAY STRUCTURE OF THE B12-BINDING DOMAINS OF METHIONINE SYNTHASE
Descriptor:METHIONINE SYNTHASE, CO-METHYLCOBALAMIN
Authors:Drennan, C.L., Huang, S., Drummond, J.T., Matthews, R.G., Ludwig, M.L.
Deposit date:1994-09-02
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase.
Science, 266, 1994
1CZU
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REFINED STRUCTURES OF OXIDIZED FLAVODOXIN FROM ANACYSTIS NIDULANS
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Drennan, C.L., Pattridge, K.A., Weber, C.H., Metzger, A.L., Hoover, D.M., Ludwig, M.L.
Deposit date:1999-09-07
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined structures of oxidized flavodoxin from Anacystis nidulans.
J.Mol.Biol., 294, 1999
1D03
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REFINED STRUCTURES OF OXIDIZED FLAVODOXIN FROM ANACYSTIS NIDULANS
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Drennan, C.L., Pattridge, K.A., Weber, C.H., Metzger, A.L., Hoover, D.M., Ludwig, M.L.
Deposit date:1999-09-08
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Refined structures of oxidized flavodoxin from Anacystis nidulans.
J.Mol.Biol., 294, 1999
1JQK
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CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM
Descriptor:carbon monoxide dehydrogenase, FE (II) ION, IRON/SULFUR CLUSTER, ...
Authors:Drennan, C.L., Heo, J., Sintchak, M.D., Schreiter, E., Ludden, P.W.
Deposit date:2001-08-07
Release date:2001-10-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Life on carbon monoxide: X-ray structure of Rhodospirillum rubrum Ni-Fe-S carbon monoxide dehydrogenase.
Proc.Natl.Acad.Sci.USA, 98, 2001
3SCF
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FE(II)-HPPE WITH S-HPP AND NO
Descriptor:Epoxidase, FE (II) ION, NITRIC OXIDE, ...
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
3SCG
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FE(II)-HPPE WITH R-HPP
Descriptor:Epoxidase, [(2R)-2-hydroxypropyl]phosphonic acid, FE (II) ION
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
3SCH
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CO(II)-HPPE WITH R-HPP
Descriptor:Epoxidase, [(2R)-2-hydroxypropyl]phosphonic acid, COBALT (II) ION
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
4J1W
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CRYSTAL STRUCTURE OF FE(II)-HPPE WITH ALTERNATIVE SUBSTRATE (R)-1-HPP
Descriptor:Epoxidase, FE (II) ION, [(1R)-1-hydroxypropyl]phosphonic acid, ...
Authors:Drennan, C.L., Dey, M.
Deposit date:2013-02-03
Release date:2013-04-03
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction.
Nature, 496, 2013
4J1X
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CRYSTAL STRUCTURE OF FE(II)-HPPE WITH ALTERNATIVE SUBSTRATE (S)-1-HPP
Descriptor:Epoxidase, FE (II) ION, [(1S)-1-hydroxypropyl]phosphonic acid, ...
Authors:Drennan, C.L., Dey, M.
Deposit date:2013-02-03
Release date:2013-04-03
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction.
Nature, 496, 2013
4M7T
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CRYSTAL STRUCTURE OF BTRN IN COMPLEX WITH ADOMET AND 2-DOIA
Descriptor:BtrN, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ...
Authors:Drennan, C.L., Goldman, P.J.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4XJK
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CRYSTAL STRUCTURE OF MN(II) CA(II) NA(I) BOUND CALPROTECTIN
Descriptor:Protein S100-A8, Protein S100-A9, CALCIUM ION, ...
Authors:Drennan, C.L., Bowman, S.E.J.
Deposit date:2015-01-08
Release date:2015-04-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Manganese Binding Properties of Human Calprotectin under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis.
J.Am.Chem.Soc., 137, 2015
6OUV
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1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE (DXPS) FROM DEINOCOCCUS RADIODURANS WITH METHYLACETYLPHOSPHONATE (MAP) BOUND
Descriptor:1-deoxy-D-xylulose-5-phosphate synthase, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ...
Authors:Chen, P.Y.-T., Drennan, C.L.
Deposit date:2019-05-05
Release date:2019-07-03
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.937 Å)
Cite:X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate.
J.Biol.Chem., 294, 2019
6OUW
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1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE (DXPS) FROM DEINOCOCCUS RADIODURANS WITH ENAMINE INTERMEDIATE BOUND
Descriptor:1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chen, P.Y.-T., Drennan, C.L.
Deposit date:2019-05-05
Release date:2019-07-03
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate.
J.Biol.Chem., 294, 2019
1CZH
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, SULFATE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-03
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1CZK
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-03
Release date:2000-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1CZL
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-03
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1CZO
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-03
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1CZR
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-07
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1D04
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COMPARISONS OF WILD TYPE AND MUTANT FLAVODOXINS FROM ANACYSTIS NIDULANS. STRUCTURAL DETERMINANTS OF THE REDOX POTENTIALS.
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Hoover, D.M., Drennan, C.L., Metzger, A.L., Osborne, C., Weber, C.H., Pattridge, K.A., Ludwig, M.L.
Deposit date:1999-09-08
Release date:1999-12-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.
J.Mol.Biol., 294, 1999
1L1L
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CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE
Descriptor:RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE
Authors:Sintchak, M.D., Arjara, G., Kellogg, B.A., Stubbe, J., Drennan, C.L.
Deposit date:2002-02-18
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
Nat.Struct.Biol., 9, 2002
1MJG
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CRYSTAL STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE(CODH/ACS) FROM MOORELLA THERMOACETICA (F. CLOSTRIDIUM THERMOACETICUM)
Descriptor:CARBON MONOXIDE DEHYDROGENASE BETA SUBUNIT, Carbon monoxide dehydrogenase alpha subunit, IRON/SULFUR CLUSTER, ...
Authors:Doukov, T.I., Iverson, T.M., Seravalli, J., Ragsdale, S.W., Drennan, C.L.
Deposit date:2002-08-27
Release date:2003-01-28
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase
Science, 298, 2002
1Q5V
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APO-NIKR
Descriptor:Nickel responsive regulator
Authors:Schreiter, E.R., Sintchak, M.D., Guo, Y., Chivers, P.T., Sauer, R.T., Drennan, C.L.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
1Q5Y
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NICKEL-BOUND C-TERMINAL REGULATORY DOMAIN OF NIKR
Descriptor:Nickel responsive regulator, NICKEL (II) ION, 1,2-ETHANEDIOL
Authors:Schreiter, E.R., Sintchak, M.D., Guo, Y., Chivers, P.T., Sauer, R.T., Drennan, C.L.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
1R30
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THE CRYSTAL STRUCTURE OF BIOTIN SYNTHASE, AN S-ADENOSYLMETHIONINE-DEPENDENT RADICAL ENZYME
Descriptor:Biotin synthase, S-ADENOSYLMETHIONINE, IRON/SULFUR CLUSTER, ...
Authors:Berkovitch, F., Nicolet, Y., Wan, J.T., Jarrett, J.T., Drennan, C.L.
Deposit date:2003-09-30
Release date:2004-01-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.
Science, 303, 2004
1T3I
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STRUCTURE OF SLR0077/SUFS, THE ESSENTIAL CYSTEINE DESULFURASE FROM SYNECHOCYSTIS PCC 6803
Descriptor:Probable cysteine desulfurase, 3-N-OCTANOYLSUCROSE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Tirupati, B., Vey, J.L., Drennan, C.L., Bollinger Jr., J.M.
Deposit date:2004-04-26
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Kinetic and structural characterization of Slr0077/SufS, the essential cysteine desulfurase from Synechocystis sp. PCC 6803.
Biochemistry, 43, 2004