4J1X

Crystal Structure of Fe(II)-HppE with alternative substrate (S)-1-HPP

Summary for 4J1X

Entry DOI	10.2210/pdb4j1x/pdb
Related	1ZZ7 1ZZ8 3SCF 3SCG 4J1W
Descriptor	Epoxidase, FE (II) ION, [(1S)-1-hydroxypropyl]phosphonic acid, ... (5 entities in total)
Functional Keywords	keto product, hydroxypropylphosphonic acid epoxidase, mononuclear non-heme iron enzyme, metal binding protein, cupin fold, phosphono migration
Biological source	Streptomyces wedmorensis
Total number of polymer chains	3
Total formula weight	64369.65
Authors	Drennan, C.L.,Dey, M. (deposition date: 2013-02-03, release date: 2013-04-03, Last modification date: 2023-09-20)
Primary citation	Chang, W.C.,Dey, M.,Liu, P.,Mansoorabadi, S.O.,Moon, S.J.,Zhao, Z.K.,Drennan, C.L.,Liu, H.W. Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature, 496:114-118, 2013 Cited by PubMed: 23552950 DOI: 10.1038/nature11998 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation