4XJK

Crystal structure of Mn(II) Ca(II) Na(I) bound calprotectin

Summary for 4XJK

• Entry DOI: 10.2210/pdb4xjk/pdb
• Descriptor: Protein S100-A8, Protein S100-A9, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: ef-hand calcium binding, metal ion binding, immune system process, inflammatory response, metal binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 121332.46

Authors

Drennan, C.L.,Bowman, S.E.J. (deposition date: 2015-01-08, release date: 2015-04-15, Last modification date: 2023-09-27)

• Primary citation: Gagnon, D.M.,Brophy, M.B.,Bowman, S.E.,Stich, T.A.,Drennan, C.L.,Britt, R.D.,Nolan, E.M.; Manganese Binding Properties of Human Calprotectin under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis.; J.Am.Chem.Soc., 137:3004-3016, 2015; PubMed: 25597447; DOI: 10.1021/ja512204s

Experimental method

X-RAY DIFFRACTION (1.76 Å)