4XJK
Crystal structure of Mn(II) Ca(II) Na(I) bound calprotectin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I (A, C, E, G, I) | Protein S100-A8 | polymer | 93 | 10837.5 | 5 | UniProt (P05109) Pfam (PF01023) | Homo sapiens (Human) | Calgranulin-A,Calprotectin L1L subunit,Cystic fibrosis antigen,CFAG,Leukocyte L1 complex light chain,Migration inhibitory factor-related protein 8,p8,S100 calcium-binding protein A8,Urinary stone protein band A |
| 2 | B, D, F, H, J (B, D, F, H, J) | Protein S100-A9 | polymer | 114 | 13248.0 | 5 | UniProt (P06702) Pfam (PF01023) | Homo sapiens (Human) | Calgranulin-B,Calprotectin L1H subunit,Leukocyte L1 complex heavy chain,Migration inhibitory factor-related protein 14,p14,S100 calcium-binding protein A9 |
| 3 | CA, EA, HA, K, N... (H, I, J, A, B...) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 4 | AA, DA, FA, IA, L... (G, H, I, J, A...) | SODIUM ION | non-polymer | 23.0 | 10 | Chemie (NA) | |||
| 5 | BA, GA, M, R, W (G, I, A, C, E) | MANGANESE (II) ION | non-polymer | 54.9 | 5 | Chemie (MN) | |||
| 6 | JA, KA, LA, MA, NA... (A, B, C, D, E...) | water | water | 18.0 | 704 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I: 1 - 93 (UniProt: P05109)
B, D, F, H, J: 1 - 114 (UniProt: P06702)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | Cys 42 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 120427.1 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 905.4 | |
| All* | Total formula weight | 121332.5 |
