Author results

3PII
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CRYSTAL STRUCTURE OF MUTANT OF HT- ALCOHOL DEHYDROGENASE WITH SUBSTRATE ANALOGUE BUTYRAMIDE
Descriptor:Alcohol dehydrogenase, ZINC ION, BUTYRAMIDE, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2010-11-06
Release date:2011-11-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of mutant of ht- Alcohol dehydrogenase
To be Published
3TK0
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MUTATION OF SFALR
Descriptor:FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Dong, M., Bahnson, B.J.
Deposit date:2011-08-25
Release date:2012-08-29
Method:X-RAY DIFFRACTION (1.611 Å)
Cite:sfALR mutation
To be Published
4LDK
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FAD-LINKED SULFHYDRYL OXIDASE ALR MUTATION
Descriptor:FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION
Authors:Dong, M., Ramadan, S., Thorpe, C., Bahnson, B.
Deposit date:2013-06-24
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:FAD-linked sulfhydryl oxidase ALR mutation
To be Published
5T9I
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5T9K
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5T9Q
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAC
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAD
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAE
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-09
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAI
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-10
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAJ
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-10
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
5TAK
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CONFORMATIONAL SAMPLING DIFFERENCES ACROSS THE ARRHENIUS PLOT BIPHASIC BREAK POINT AT AMBIENT TEMPERATURE IN THE ENZYME THERMOLYSIN
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:Dong, M., Bahnson, B.J.
Deposit date:2016-09-10
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
3MBG
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CRYSTAL STRUCTURE OF HUMAN AUGMENTER OF LIVER REGENERATION (ALR)
Descriptor:FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ...
Authors:Dong, M., Schaefer, S., Daithankar, V.N., Thorpe, C., Bahnson, B.J.
Deposit date:2010-03-25
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy .
Biochemistry, 49, 2010
3U5S
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SELENIUM SUBSTITUTED HUMAN AUGMENTER OF LIVER REGENERATION
Descriptor:FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Dong, M., Bahnson, B.J.
Deposit date:2011-10-11
Release date:2012-10-17
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:(77)Se enrichment of proteins expands the biological NMR toolbox.
J.Mol.Biol., 425, 2013
6BXK
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CRYSTAL STRUCTURE OF PYROCOCCUS HORIKOSHII DPH2 WITH 4FE-4S CLUSTER AND MTA
Descriptor:2-(3-amino-3-carboxypropyl)histidine synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, SULFATE ION, ...
Authors:Torelli, A.T., Fenwick, M.K., Zhang, Y., Dong, M., Kathiresan, V., Carantoa, J.D., Dzikovski, B., Lancaster, K.M., Freed, J.H., Hoffman, B.M., Lin, H., Ealick, S.E.
Deposit date:2017-12-18
Release date:2018-04-11
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
Science, 359, 2018
6BXL
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CRYSTAL STRUCTURE OF PYROCOCCUS HORIKOSHII DPH2 WITH 4FE-4S CLUSTER AND SAM
Descriptor:2-(3-amino-3-carboxypropyl)histidine synthase, S-ADENOSYLMETHIONINE, IRON/SULFUR CLUSTER
Authors:Torelli, A.T., Fenwick, M.K., Zhang, Y., Dong, M., Kathiresan, V., Carantoa, J.D., Dzikovski, B., Lancaster, K.M., Freed, J.H., Hoffman, B.M., Lin, H., Ealick, S.E.
Deposit date:2017-12-18
Release date:2018-04-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
Science, 359, 2018
6BXM
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CRYSTAL STRUCTURE OF CANDIDATUS METHANOPEREDENS NITROREDUCENS DPH2 WITH 4FE-4S CLUSTER AND SAM/CLEAVED SAM
Descriptor:Diphthamide biosynthesis enzyme Dph2, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ...
Authors:Fenwick, M.K., Torelli, A.T., Zhang, Y., Dong, M., Kathiresan, V., Carantoa, J.D., Dzikovski, B., Lancaster, K.M., Freed, J.H., Hoffman, B.M., Lin, H., Ealick, S.E.
Deposit date:2017-12-18
Release date:2018-04-11
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
Science, 359, 2018
6BXN
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CRYSTAL STRUCTURE OF CANDIDATUS METHANOPEREDENS NITROREDUCENS DPH2 WITH 4FE-4S CLUSTER AND SAM
Descriptor:Diphthamide biosynthesis enzyme Dph2, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE
Authors:Fenwick, M.K., Torelli, A.T., Zhang, Y., Dong, M., Kathiresan, V., Carantoa, J.D., Dzikovski, B., Lancaster, K.M., Freed, J.H., Hoffman, B.M., Lin, H., Ealick, S.E.
Deposit date:2017-12-18
Release date:2018-04-11
Method:X-RAY DIFFRACTION (2.079 Å)
Cite:Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
Science, 359, 2018
6BXO
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CRYSTAL STRUCTURE OF CANDIDATUS METHANOPEREDENS NITROREDUCENS DPH2 WITH 4FE-4S CLUSTER AND SAH
Descriptor:Diphthamide biosynthesis enzyme Dph2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Fenwick, M.K., Torelli, A.T., Zhang, Y., Dong, M., Kathiresan, V., Carantoa, J.D., Dzikovski, B., Lancaster, K.M., Freed, J.H., Hoffman, B.M., Lin, H., Ealick, S.E.
Deposit date:2017-12-18
Release date:2018-04-11
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
Science, 359, 2018
5JLV
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH HUMAN GLYCOSYLATED SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C, ACETATE ION, ...
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH RAT SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
6G5F
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CRYSTAL STRUCTURE OF AN ENGINEERED BOTULINUM NEUROTOXIN TYPE B MUTANT E1191M/S1199Y IN COMPLEX WITH HUMAN SYNAPTOTAGMIN 1
Descriptor:Botulinum neurotoxin type B, Synaptotagmin-1, GLYCEROL, ...
Authors:Masuyer, G., Elliot, M., Favre-Guilmard, C., Liu, S.M., Maignel, J., Beard, M., Carre, D., Kalinichev, M., Lezmi, S., Mir, I., Nicoleau, C., Palan, S., Perier, C., Raban, E., Dong, M., Krupp, J., Stenmark, P.
Deposit date:2018-03-29
Release date:2019-01-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Sci Adv, 5, 2019
6G5G
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CRYSTAL STRUCTURE OF AN ENGINEERED BOTULINUM NEUROTOXIN TYPE B MUTANT E1191M/S1199Y IN COMPLEX WITH HUMAN SYNAPTOTAGMIN 2
Descriptor:Botulinum neurotoxin type B, Synaptotagmin 2, MAGNESIUM ION, ...
Authors:Masuyer, G., Elliot, M., Favre-Guilmard, C., Liu, S.M., Maignel, J., Beard, M., Carre, D., Kalinichev, M., Lezmi, S., Mir, I., Nicoleau, C., Palan, S., Perier, C., Raban, E., Dong, M., Krupp, J., Stenmark, P.
Deposit date:2018-03-29
Release date:2019-01-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Sci Adv, 5, 2019
6G5K
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CRYSTAL STRUCTURE OF THE BINDING DOMAIN OF BOTULINUM NEUROTOXIN TYPE B IN COMPLEX WITH HUMAN SYNAPTOTAGMIN 1
Descriptor:Botulinum neurotoxin type B, Synaptotagmin-1
Authors:Masuyer, G., Elliot, M., Favre-Guilmard, C., Liu, S.M., Maignel, J., Beard, M., Carre, D., Kalinichev, M., Lezmi, S., Mir, I., Nicoleau, C., Palan, S., Perier, C., Raban, E., Dong, M., Krupp, J., Stenmark, P.
Deposit date:2018-03-29
Release date:2019-01-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Sci Adv, 5, 2019
4ISQ
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BINDING DOMAIN OF BOTULINUM NEUROTOXIN DC IN COMPLEX WITH HUMAN SYNAPTOTAGMIN I
Descriptor:Neurotoxin, Synaptotagmin-1, SULFATE ION, ...
Authors:Berntsson, R.P.-A., Peng, L., Svensson, L.M., Dong, M., Stenmark, P.
Deposit date:2013-01-17
Release date:2013-08-14
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
Structure, 21, 2013
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