Author results

1YTS
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A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE
Descriptor:YERSINIA PROTEIN TYROSINE PHOSPHATASE, SULFATE ION
Authors:Schubert, H.L., Stuckey, J.A., Fauman, E.B., Dixon, J.E., Saper, M.A.
Deposit date:1995-04-07
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Protein Sci., 4, 1995
1VHR
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HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE
Descriptor:HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
Authors:Yuvaniyama, J., Denu, J.M., Dixon, J.E., Saper, M.A.
Deposit date:1996-02-20
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
1YPT
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CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE
Descriptor:PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN)
Authors:Stuckey, J.A., Schubert, H.L., Fauman, E.B., Zhang, Z.-Y., Dixon, J.E., Saper, M.A.
Deposit date:1994-09-16
Release date:1994-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature, 370, 1994
1BYR
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CRYSTAL STRUCTURE OF A PHOSPHOLIPASE D FAMILY MEMBER, NUC FROM SALMONELLA TYPHIMURIUM
Descriptor:PROTEIN (ENDONUCLEASE)
Authors:Stuckey, J.A., Dixon, J.E.
Deposit date:1998-10-19
Release date:1999-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
1BYS
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CRYSTAL STRUCTURE OF NUC COMPLEXED WITH TUNGSTATE
Descriptor:PROTEIN (ENDONUCLEASE), TUNGSTATE(VI)ION
Authors:Stuckey, J.A., Dixon, J.E.
Deposit date:1998-10-19
Release date:1999-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
1DOF
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THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY
Descriptor:ADENYLOSUCCINATE LYASE
Authors:Toth, E.A., Yeates, T.O., Goedken, E., Dixon, J.E., Marqusee, S.
Deposit date:1999-12-20
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
1LW3
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CRYSTAL STRUCTURE OF MYOTUBULARIN-RELATED PROTEIN 2 COMPLEXED WITH PHOSPHATE
Descriptor:Myotubularin-related protein 2, PHOSPHATE ION
Authors:Begley, M.J., Taylor, G.S., Kim, S.-A., Veine, D.M., Dixon, J.E., Stuckey, J.A.
Deposit date:2002-05-30
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Phosphoinositide Phosphatase, MTMR2: Insights into Myotubular Myopathy and Charcot-Marie-Tooth Syndrome
Mol.Cell, 12, 2003
1M7R
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CRYSTAL STRUCTURE OF MYOTUBULARIN-RELATED PROTEIN-2 (MTMR2) COMPLEXED WITH PHOSPHATE
Descriptor:Myotubularin-related Protein-2, PHOSPHATE ION
Authors:Begley, M.J., Taylor, G.S., Kim, S.-A., Veine, D.M., Dixon, J.E., Stuckey, J.A.
Deposit date:2002-07-22
Release date:2003-10-07
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome
Mol.Cell, 12, 2003
1UKF
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CRYSTAL STRUCTURE OF PSEUDOMONAS AVIRULENCE PROTEIN AVRPPHB
Descriptor:Avirulence protein AVRPPH3
Authors:Zhu, M., Shao, F., Innes, R.W., Dixon, J.E., Xu, Z.
Deposit date:2003-08-21
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1ZSQ
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CRYSTAL STRUCTURE OF MTMR2 IN COMPLEX WITH PHOSPHATIDYLINOSITOL 3-PHOSPHATE
Descriptor:Myotubularin-related protein 2, 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE
Authors:Begley, M.J., Taylor, G.S., Brock, M.A., Ghosh, P., Woods, V.L., Dixon, J.E.
Deposit date:2005-05-25
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZVR
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CRYSTAL STRUCTURE OF MTMR2 IN COMPLEX WITH PHOSPHATIDYLINOSITOL 3,5-BISPHOSPHATE
Descriptor:Myotubularin-related protein 2, 1,2-ETHANEDIOL, (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE
Authors:Begley, M.J., Taylor, G.S., Brock, M.A., Ghosh, P., Woods, V.L., Dixon, J.E.
Deposit date:2005-06-02
Release date:2006-01-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase
Proc.Natl.Acad.Sci.Usa, 103, 2006
2QH7
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MITONEET IS A UNIQUELY FOLDED 2FE-2S OUTER MITOCHONDRIAL MEMBRANE PROTEIN STABILIZED BY PIOGLITAZONE
Descriptor:Zinc finger CDGSH-type domain 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Paddock, M.L., Wiley, S.E., Axelrod, H.L., Cohen, A.E., Roy, M., Abresch, E.C., Capraro, D., Murphy, A.N., Nechushtai, R., Dixon, J.E., Jennings, P.A.
Deposit date:2007-06-30
Release date:2007-08-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4ITR
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CRYSTAL STRUCTURE OF IBPAFIC2-H3717A IN COMPLEX WITH ADENYLYLATED CDC42
Descriptor:Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, SULFATE ION, ...
Authors:Xiao, J., Dixon, J.E.
Deposit date:2013-01-18
Release date:2013-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of Fic-mediated adenylylation.
Nat.Struct.Mol.Biol., 17, 2010
1YTN
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HYDROLASE
Descriptor:YERSINIA PROTEIN TYROSINE PHOSPHATASE, NITRATE ION
Authors:Yuvaniyama, C., Fauman, E.B., Saper, M.A.
Deposit date:1996-05-01
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications.
J.Biol.Chem., 271, 1996
1YTW
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YERSINIA PTPASE COMPLEXED WITH TUNGSTATE
Descriptor:YERSINIA PROTEIN TYROSINE PHOSPHATASE, TUNGSTATE(VI)ION, SULFATE ION
Authors:Fauman, E.B., Schubert, H.L., Saper, M.A.
Deposit date:1996-05-01
Release date:1996-11-08
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications.
J.Biol.Chem., 271, 1996
2I42
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CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE COMPLEXED WITH VANADATE, A TRANSITION STATE ANALOGUE
Descriptor:Tyrosine-protein phosphatase, VANADATE ION
Authors:Vijayalakshmi, J., Saper, M.A.
Deposit date:2006-08-21
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
To be Published
5ZTN
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THE CRYSTAL STRUCTURE OF HUMAN DYRK2 IN COMPLEX WITH CURCUMIN
Descriptor:Dual specificity tyrosine-phosphorylation-regulated kinase 2, (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
Authors:Ji, C.G., Xiao, J.Y.
Deposit date:2018-05-04
Release date:2018-07-18
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1D5R
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CRYSTAL STRUCTURE OF THE PTEN TUMOR SUPPRESSOR
Descriptor:PHOSPHOINOSITIDE PHOSPHATASE PTEN, L(+)-TARTARIC ACID
Authors:Lee, J.O., Yang, H., Georgescu, M.-M., Di Cristofano, A., Pavletich, N.P.
Deposit date:1999-10-11
Release date:1999-11-04
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99, 1999
1F1O
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STRUCTURAL STUDIES OF ADENYLOSUCCINATE LYASES
Descriptor:ADENYLOSUCCINATE LYASE
Authors:Toth, E.A., Yeates, T.
Deposit date:2000-05-19
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
2GHQ
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CTD-SPECIFIC PHOSPHATASE SCP1 IN COMPLEX WITH PEPTIDE C-TERMINAL DOMAIN OF RNA POLYMERASE II
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y., Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2GHT
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CTD-SPECIFIC PHOSPHATASE SCP1 IN COMPLEX WITH PEPTIDE FROM C-TERMINAL DOMAIN OF RNA POLYMERASE II
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y., Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
3CXB
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CRYSTAL STRUCTURE OF SIFA AND SKIP
Descriptor:Protein sifA, Pleckstrin homology domain-containing family M member 2
Authors:Huang, Z., Chai, J.
Deposit date:2008-04-24
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation
Cell Host Microbe, 4, 2008
3L0B
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CRYSTAL STRUCTURE OF SCP1 PHOSPHATASE D206A MUTANT PHOSPHORYL-INTERMEDIATE
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL
Authors:Zhang, M., Zhang, Y.
Deposit date:2009-12-09
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
3L0C
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CRYSTAL STRUCTURE OF SCP1 PHOSPHATASE D206A MUTANT WITH TRAPPED INORGANIC PHOSPHATE
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, PHOSPHATE ION
Authors:Zhang, M., Zhang, Y.
Deposit date:2009-12-09
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
3L0Y
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CRYSTAL STRUCTURE OF SCP1 PHOSPHATASE D98A MUTANT
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Zhang, M., Zhang, Y.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
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