Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6Y0D
DownloadVisualize
BU of 6y0d by Molmil
Crystal structure of Trypanosoma cruzi antigen TcSMP11.90
Descriptor: Surface membrane protein
Authors:Di Pisa, F, Gourlay, L.J, Bolognesi, M, De Benedetti, S.
Deposit date:2020-02-07
Release date:2022-02-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease.
Vaccines (Basel), 10, 2022
5T7O
DownloadVisualize
BU of 5t7o by Molmil
Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase in complex with (6S)-5,6,7,8-TETRAHYDROFOLATE
Descriptor: (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ...
Authors:Di Pisa, F, Dello Iacono, L, Bonucci, A, Mangani, S.
Deposit date:2016-09-05
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase in complex with (6S)-5,6,7,8-TETRAHYDROFOLATE
To Be Published
7PXX
DownloadVisualize
BU of 7pxx by Molmil
The crystal structure of Leishmania major Pteridine Reductase 1 in complex with substrate folic acid
Descriptor: DI(HYDROXYETHYL)ETHER, FOLIC ACID, GLYCEROL, ...
Authors:Di Pisa, F, Dello Iacono, L, Mangani, S.
Deposit date:2021-10-08
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP + /NADPH and the substrate folic acid.
Acta Crystallogr.,Sect.F, 78, 2022
6YC8
DownloadVisualize
BU of 6yc8 by Molmil
Crystal structure of KRED1-Pglu enzyme
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Di Pisa, F.
Deposit date:2020-03-18
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction.
Bioorg.Chem., 108, 2021
5NJW
DownloadVisualize
BU of 5njw by Molmil
Crystal Structure of BJP-1 metallo beta-lactamase in complex with boric acid
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, Blr6230 protein, ...
Authors:Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S.
Deposit date:2017-03-29
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Boric acid and acetate anion binding to subclass B3 metallo-Beta-lactamase BJP-1 provides clues for mechanism of action and inhibitor design
Inorg.Chim.Acta., 2017
5NGG
DownloadVisualize
BU of 5ngg by Molmil
Crystal structure of the subclass B3 metallo-beta-lactamase BJP-1 in complex with acetate anion
Descriptor: ACETATE ION, Blr6230 protein, ZINC ION
Authors:Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S.
Deposit date:2017-03-17
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Boric acid and acetate anion binding to subclass B3 metallo-Beta-lactamase BJP-1 provides clues for mechanism of action and inhibitor design
Inorg.Chim.Acta., 2017
5L4N
DownloadVisualize
BU of 5l4n by Molmil
Leishmania major Pteridine reductase 1 (PTR1) in complex with compound 1
Descriptor: (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Dello Iacono, L, Di Pisa, F, Pozzi, C, Landi, G, Mangani, S.
Deposit date:2016-05-26
Release date:2017-03-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Molecules, 22, 2017
5L42
DownloadVisualize
BU of 5l42 by Molmil
Leishmania major Pteridine reductase 1 (PTR1) in complex with compound 3
Descriptor: (2~{R})-2-[3,4-bis(oxidanyl)phenyl]-6-oxidanyl-2,3-dihydrochromen-4-one, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Dello Iacono, L, Di Pisa, F, Pozzi, C, Landi, G, Mangani, S.
Deposit date:2016-05-24
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Molecules, 22, 2017
5K6A
DownloadVisualize
BU of 5k6a by Molmil
Trypanosoma brucei Pteridine reductase 1 (PTR1) in complex with compound 1
Descriptor: (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Landi, G, Pozzi, C, Di Pisa, F, Dello lacono, L, Mangani, S.
Deposit date:2016-05-24
Release date:2017-03-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Molecules, 22, 2017
6RXC
DownloadVisualize
BU of 6rxc by Molmil
Leishmania major pteridine reductase 1 (LmPTR1) in complex with inhibitor 4 (NMT-C0026)
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase 1, methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate
Authors:Di Pisa, F, Dello Iacono, L, Pozzi, C, Mangani, S.
Deposit date:2019-06-07
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J.Med.Chem., 65, 2022
8QOV
DownloadVisualize
BU of 8qov by Molmil
Capra hircus reactive intermediate deaminase A mutant - I126Y
Descriptor: 1,2-ETHANEDIOL, 2-iminobutanoate/2-iminopropanoate deaminase, DI(HYDROXYETHYL)ETHER, ...
Authors:Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S.
Deposit date:2023-09-29
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capra hircus reactive intermediate deaminase A mutant - I126Y
To Be Published
8QOS
DownloadVisualize
BU of 8qos by Molmil
Capra hircus reactive intermediate deaminase A - V25W
Descriptor: 1,2-ETHANEDIOL, 2-iminobutanoate/2-iminopropanoate deaminase, POTASSIUM ION
Authors:Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S.
Deposit date:2023-09-29
Release date:2024-06-26
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Capra hircus reactive intermediate deaminase A - V25W
To Be Published
8QOM
DownloadVisualize
BU of 8qom by Molmil
Capra hircus reactive intermediate deaminase A mutant - R107W
Descriptor: 2-iminobutanoate/2-iminopropanoate deaminase
Authors:Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S.
Deposit date:2023-09-29
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.654 Å)
Cite:Capra hircus reactive intermediate deaminase A mutant - R107W
To Be Published
4WCF
DownloadVisualize
BU of 4wcf by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor 9
Descriptor: 3-(5-amino-1,3,4-thiadiazol-2-yl)pyridin-4-amine, ACETATE ION, GLYCEROL, ...
Authors:Mangani, S, Di Pisa, F, Pozzi, C.
Deposit date:2014-09-04
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
4WCD
DownloadVisualize
BU of 4wcd by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor 10
Descriptor: 5-(1H-benzotriazol-6-yl)-1,3,4-thiadiazol-2-amine, ACETATE ION, GLYCEROL, ...
Authors:Mangani, S, Di Pisa, F, Pozzi, C.
Deposit date:2014-09-04
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
4Y08
DownloadVisualize
BU of 4y08 by Molmil
ONE MINUTE IRON LOADED HUMAN H FERRITIN
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin heavy chain, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2015-02-05
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Iron binding to human heavy-chain ferritin.
Acta Crystallogr.,Sect.D, 71, 2015
6I9P
DownloadVisualize
BU of 6i9p by Molmil
Iron-free state of Rana catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, Ferritin, middle subunit, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-24
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
6I9T
DownloadVisualize
BU of 6i9t by Molmil
Two minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-25
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
6I36
DownloadVisualize
BU of 6i36 by Molmil
SIXTY MINUTES IRON LOADED FROG M FERRITIN
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Mangani, S, Di Pisa, F, Pozzi, C, Turano, P, Lalli, D.
Deposit date:2018-11-05
Release date:2018-12-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Time-Lapse Anomalous X-Ray Diffraction Shows How Fe(2+) Substrate Ions Move Through Ferritin Protein Nanocages To Oxidoreductase Sites.
Acta Crystallogr.,Sect.D, 71, 2015
6IAJ
DownloadVisualize
BU of 6iaj by Molmil
Sixty minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-26
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
6IAF
DownloadVisualize
BU of 6iaf by Molmil
Fifteen minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-26
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
5JCJ
DownloadVisualize
BU of 5jcj by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor NMT-H037 (compound 7)
Descriptor: 2-(3,4-dihydroxyphenyl)-3,6-dihydroxy-4H-1-benzopyran-4-one, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Landi, G, Pozzi, C, Di Pisa, F, Dello Iacono, L, Mangani, S.
Deposit date:2016-04-15
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016
8QOU
DownloadVisualize
BU of 8qou by Molmil
Reactive intermediate deaminase A mutant - R107K
Descriptor: 1,2-ETHANEDIOL, 2-iminobutanoate/2-iminopropanoate deaminase, DI(HYDROXYETHYL)ETHER, ...
Authors:Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S.
Deposit date:2023-09-29
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Reactive intermediate deaminase A mutant - R107K
To Be Published
5IZC
DownloadVisualize
BU of 5izc by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor F032
Descriptor: ACETATE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pozzi, C, Landi, G, Di Pisa, F, Mangani, S.
Deposit date:2016-03-25
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
5J93
DownloadVisualize
BU of 5j93 by Molmil
Five minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-08
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016

 

1234>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon