9DI4
 
 | | RMI1-RMI2 bound to cyclic peptide L4 | | Descriptor: | L4 cyclic peptide, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2, ... | | Authors: | Bythell-Douglas, R, Lau, Y.H, Alcock, L.J, Gao, T, Deshpande, C, Patel, K. | | Deposit date: | 2024-09-05 | | Release date: | 2025-07-02 | | Last modified: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.696 Å) | | Cite: | Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction.
J.Med.Chem., 68, 2025
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9DHK
 | | RMI1-RMI2 bound to cyclic peptide L3 | | Descriptor: | L3 peptide, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | | Authors: | Bythell-Douglas, R, Lau, Y, Alcock, L.J, Patel, K, Gao, T, Deshpande, C. | | Deposit date: | 2024-09-03 | | Release date: | 2025-07-02 | | Last modified: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction.
J.Med.Chem., 68, 2025
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3GHJ
 | | Crystal structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4 | | Descriptor: | Putative integron gene cassette protein | | Authors: | Sureshan, V, Deshpande, C, Harrop, S.J, Kudritska, M, Koenig, J.E, Evdokimova, E, Kim, Y, Edwards, A.M, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-03-03 | | Release date: | 2009-03-24 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (1.471 Å) | | Cite: | Structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4
To be Published
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9NN3
 | | BET BRD2-BD1 in complex with peptide 6.2 | | Descriptor: | Bromodomain-containing protein 2, peptide 6.2 | | Authors: | Jing, X, Deshpande, C, Patel, K, Mackay, J.P. | | Deposit date: | 2025-03-05 | | Release date: | 2026-02-11 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The effect of peptide size on target affinity in mRNA display-derived macrocyclic peptides.
Chem.Commun.(Camb.), 62, 2026
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9PFD
 | | RMI1-RMI2 bound to synthetic peptide P4Ser | | Descriptor: | P4Ser peptide, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | | Authors: | Bythell-Douglas, R, Lau, Y.H, Alcock, L.J, Deshpande, C. | | Deposit date: | 2025-07-04 | | Release date: | 2026-02-04 | | Method: | X-RAY DIFFRACTION (2.008 Å) | | Cite: | Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction.
J.Med.Chem., 68, 2025
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8D4Y
 | | C-terminal SANT-SLIDE domain of human Chromodomain-helicase-DNA-binding protein 4 (CHD4) | | Descriptor: | Chromodomain-helicase-DNA-binding protein 4 | | Authors: | Moghaddas Sani, H, Deshpande, C.N, Panjikar, S, Patel, K, Mackay, J.P. | | Deposit date: | 2022-06-03 | | Release date: | 2022-12-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families.
Nat Commun, 13, 2022
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8TX8
 | | Crystal Structure of RBBP4 bound to ZNF512B peptide | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FORMIC ACID, ... | | Authors: | Deshpande, C.N, Mackay, J.P. | | Deposit date: | 2023-08-22 | | Release date: | 2024-11-06 | | Last modified: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | ZNF512B binds RBBP4 via a variant NuRD interaction motif and aggregates chromatin in a NuRD complex-independent manner.
Nucleic Acids Res., 52, 2024
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3JRT
 | | Structure from the mobile metagenome of V. paracholerae: Integron cassette protein Vpc_cass2 | | Descriptor: | Integron cassette protein Vpc_cass2 | | Authors: | Harrop, S.J, Deshpande, C, Sureshan, V, Boucher, Y, Xu, X, Cui, H, Cuff, M, Edwards, A, Savchenko, A, Joachimiak, A, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-09-08 | | Release date: | 2009-09-22 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
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3FXH
 | | Crystal structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS2 | | Descriptor: | Integron gene cassette protein HFX_CASS2 | | Authors: | Sureshan, V, Deshpande, C, Harrop, S.J, Kudritska, M, Koenig, J.E, Evdokimova, E, Chang, C, Edwards, A.M, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-01-20 | | Release date: | 2009-02-17 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.837 Å) | | Cite: | Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
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3FYN
 | | Crystal structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3 | | Descriptor: | ACETATE ION, Integron gene cassette protein HFX_CASS3, MAGNESIUM ION | | Authors: | Sureshan, V, Deshpande, C.N, Harrop, S.J, Kudritska, M, Koenig, J.E, Evdokimova, E, Osipiuk, J, Edwards, A.M, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-01-22 | | Release date: | 2009-02-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.449 Å) | | Cite: | Structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3
To be Published
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9ECP
 | | Structure of the native human NCP purified from HEK293 cells | | Descriptor: | DNA (145-MER), Histone H2A type 3, Histone H2B type 1-K, ... | | Authors: | Reid, X.J, Sobti, M, Low, J.K.K, Stewart, A.G, Mackay, J.P. | | Deposit date: | 2024-11-14 | | Release date: | 2025-10-22 | | Method: | ELECTRON MICROSCOPY (1.91 Å) | | Cite: | The structure and composition of native human nucleosomes
Biorxiv, 2025
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9NN5
 | | BET BRD4-BD1 in complex with peptide 9.2 | | Descriptor: | Bromodomain-containing protein 4, peptide 9.2 | | Authors: | Jing, X, Mackay, J.P. | | Deposit date: | 2025-03-05 | | Release date: | 2026-02-11 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | The effect of peptide size on target affinity in mRNA display-derived macrocyclic peptides.
Chem.Commun.(Camb.), 62, 2026
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9NN4
 | | BET BRD3-BD1 in complex with peptide 7.2 | | Descriptor: | Bromodomain-containing protein 3, peptide 7.2 | | Authors: | Jing, X, Mackay, J.P. | | Deposit date: | 2025-03-05 | | Release date: | 2026-02-11 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | The effect of peptide size on target affinity in mRNA display-derived macrocyclic peptides.
Chem.Commun.(Camb.), 62, 2026
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9NNT
 | | BET BRD4-BD1 in complex with peptide 6.1 | | Descriptor: | Bromodomain-containing protein 4, peptide 6.1 | | Authors: | Jing, X. | | Deposit date: | 2025-03-06 | | Release date: | 2026-02-11 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The effect of peptide size on target affinity in mRNA display-derived macrocyclic peptides.
Chem.Commun.(Camb.), 62, 2026
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