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4NFZ
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BU of 4nfz by Molmil
Crystal structure of polymerase subunit PA N-terminal endonuclease domain from bat-derived influenza virus H17N10
Descriptor: MANGANESE (II) ION, Polymerase PA
Authors:Tefsen, B, Lu, G, Zhu, Y, Haywood, J, Zhao, L, Deng, T, Qi, J, Gao, G.F.
Deposit date:2013-11-01
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease Activity
J.Virol., 88, 2014
6KG7
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BU of 6kg7 by Molmil
Cryo-EM Structure of the Mammalian Tactile Channel Piezo2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Piezo-type mechanosensitive ion channel component 2
Authors:Wang, L, Zhou, H, Zhang, M, Liu, W, Deng, T, Zhao, Q, Li, Y, Lei, J, Li, X, Xiao, B.
Deposit date:2019-07-11
Release date:2019-09-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and mechanogating of the mammalian tactile channel PIEZO2.
Nature, 573, 2019
7VF5
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BU of 7vf5 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, and HAKAI)
Descriptor: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog
Authors:Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
Deposit date:2021-09-10
Release date:2022-09-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
7VF2
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BU of 7vf2 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, ZC3H13, and HAKAI)
Descriptor: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog, Zinc finger CCCH domain-containing protein 13
Authors:Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
Deposit date:2021-09-10
Release date:2022-09-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
8HF0
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BU of 8hf0 by Molmil
DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
8HF1
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BU of 8hf1 by Molmil
DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
4XTA
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BU of 4xta by Molmil
MECHANISMS OF PPARgamma ACTIVATION BY NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
Descriptor: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Puhl, A.C, Webb, P, Polikarpov, I.
Deposit date:2015-01-23
Release date:2015-11-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
4XUH
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BU of 4xuh by Molmil
PPARgamma ligand binding domain in complex with sulindac sulfide
Descriptor: 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Puhl, A.C, Polikaporv, I, Webb, P.
Deposit date:2015-01-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
4XUM
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BU of 4xum by Molmil
PPARgamma ligand binding domain in complex with indomethacin
Descriptor: INDOMETHACIN, Peroxisome proliferator-activated receptor gamma
Authors:Puhl, A.C, Webb, P, Polikarpov, I.
Deposit date:2015-01-26
Release date:2015-11-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
5XO0
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BU of 5xo0 by Molmil
Crystal structure of the isochorismatase domain of AngB from Vibrio anguillarum 775
Descriptor: Ischorismate lyase
Authors:Ma, Q, Du, J.
Deposit date:2017-05-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of the isochorismatase domains from Vibrio anguillarum.
Biochem.Biophys.Res.Commun., 490, 2017
3EBJ
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BU of 3ebj by Molmil
Crystal structure of an avian influenza virus protein
Descriptor: MAGNESIUM ION, Polymerase acidic protein
Authors:Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y.
Deposit date:2008-08-27
Release date:2009-02-10
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
5GLE
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BU of 5gle by Molmil
The structure of Vibrio anguillarum775 AngB-ICL
Descriptor: Ischorismate lyase
Authors:Du, J.S, Ma, Q.G.
Deposit date:2016-07-10
Release date:2017-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of Vibrio anguillarum775 AngB-ICL protein
To Be Published
4EMA
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BU of 4ema by Molmil
Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone
Descriptor: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma
Authors:Liberato, M.V, Nascimento, A.S, Polikarpov, I.
Deposit date:2012-04-11
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists
Plos One, 7, 2012
4EM9
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BU of 4em9 by Molmil
Human PPAR gamma in complex with nonanoic acids
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma, ...
Authors:Liberato, M.V, Nascimento, A.S, Polikarpov, I.
Deposit date:2012-04-11
Release date:2013-03-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists
Plos One, 7, 2012
1CEH
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BU of 1ceh by Molmil
STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Kumar, A, Sekharudu, C, Ramakrishnan, B, Dupureur, C.M, Zhu, H, Tsai, M.-D, Sundaralingam, M.
Deposit date:1994-11-16
Release date:1995-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Protein Sci., 3, 1994
8IV5
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BU of 8iv5 by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement)
Descriptor: Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ...
Authors:Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
Deposit date:2023-03-26
Release date:2023-08-16
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IVA
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BU of 8iva by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs XMA01 and 3E2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ...
Authors:Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
Deposit date:2023-03-26
Release date:2023-08-16
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IV8
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BU of 8iv8 by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4 (local refinement)
Descriptor: Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ...
Authors:Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
Deposit date:2023-03-26
Release date:2023-08-16
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IV4
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BU of 8iv4 by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ...
Authors:Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
Deposit date:2023-03-26
Release date:2023-08-16
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
5XO1
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BU of 5xo1 by Molmil
Crystal structure of the isochorismatase domain of VabB from Vibrio anguillarum 775
Descriptor: Isochorismate lyase
Authors:Ma, Q, Du, J.
Deposit date:2017-05-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structures of the isochorismatase domains from Vibrio anguillarum.
Biochem.Biophys.Res.Commun., 490, 2017
5ZQV
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BU of 5zqv by Molmil
Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GM
Descriptor: CITRATE ANION, MANGANESE (II) ION, Protein phosphatase 1 regulatory subunit 3A, ...
Authors:Yu, J, Xiang, S.
Deposit date:2018-04-20
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis for protein phosphatase 1 recruitment by glycogen-targeting subunits.
FEBS J., 285, 2018
5ZT0
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BU of 5zt0 by Molmil
Crystal Structure of Protein Phosphate 1 Complexed with PP1 binding domain of GL
Descriptor: MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1 regulatory subunit 3B, ...
Authors:Yu, J, Xiang, S.
Deposit date:2018-05-01
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3204267 Å)
Cite:Structural basis for protein phosphatase 1 recruitment by glycogen-targeting subunits
FEBS J., 285, 2018
6KUR
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BU of 6kur by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUK
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BU of 6kuk by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUP
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BU of 6kup by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019

 

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