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5M5B
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CRYSTAL STRUCTURE OF ZIKA VIRUS NS5 METHYLTRANSFERASE
Descriptor:NS5 methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Barral, K., Ortiz Lombardia, M., Coutard, B., Decroly, E., Lichiere, J.
Deposit date:2016-10-21
Release date:2016-12-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
J. Virol., 91, 2017
5IQ5
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NMR SOLUTION STRUCTURE OF MAYARO VIRUS MACRO DOMAIN
Descriptor:Macro domain
Authors:Melekis, E., Tsika, A.C., Bentrop, D., Papageorgiou, N., Coutard, B., Spyroulias, G.A.
Deposit date:2016-03-10
Release date:2017-12-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Deciphering the Nucleotide and RNA Binding Selectivity of the Mayaro Virus Macro Domain.
J.Mol.Biol., 2019
5ISN
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NMR SOLUTION STRUCTURE OF MACRO DOMAIN FROM VENEZUELAN EQUINE ENCEPHALITIS VIRUS
Descriptor:Non-structural polyprotein
Authors:Makrynitsa, G.I., Ntonti, D., Marousis, K.D., Tsika, A.C., Papageorgiou, N., Coutard, B., Bentrop, D., Spyroulias, G.A.
Deposit date:2016-03-15
Release date:2017-11-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
5MQX
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NMR SOLUTION STRUCTURE OF MACRO DOMAIN FROM VENEZUELAN EQUINE ENCEPHALITIS VIRUS(VEEV) IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Makrynitsa, G.I., Ntonti, D., Marousis, K.D., Matsoukas, M.T., Papageorgiou, N., Coutard, B., Bentrop, D., Spyroulias, G.A.
Deposit date:2016-12-21
Release date:2018-07-04
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
3JSB
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE LYMPHOCYTIC CHORIOMENINGITIS VIRUS L PROTEIN
Descriptor:RNA-directed RNA polymerase
Authors:Morin, B., Jamal, S., Ferron, F.P., Coutard, B., Bricogne, G., Canard, B., Vonrhein, C., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6, 2010
4TU0
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CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
Descriptor:Non-structural polyprotein 3, 2'-5' OLIGOADENYLATE TRIMER, DI(HYDROXYETHYL)ETHER
Authors:Morin, B., Ferron, f.p., Malet, h., Coutard, b., Canard, b.
Deposit date:2014-06-23
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
TO BE PUBLISHED
2CKW
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THE 2.3 A RESOLUTION STRUCTURE OF THE SAPPORO VIRUS RNA DEPENDANT RNA POLYMERASE.
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B., Tucker, P.A., Rohayem, J., Coutard, B., Gebhardt, J., Gorbalenya, A., Canard, B.
Deposit date:2006-04-24
Release date:2006-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
2H85
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CRYSTAL STRUCTURE OF NSP 15 FROM SARS
Descriptor:Putative orf1ab polyprotein
Authors:Ricagno, S., Egloff, M.P., Ulferts, R., Coutard, B., Nurizzo, D., Campanacci, V., Cambillau, C., Ziebuhr, J., Canard, B.
Deposit date:2006-06-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2V6I
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KOKOBERA VIRUS HELICASE
Descriptor:RNA HELICASE, PYROPHOSPHATE 2-
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V6J
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KOKOBERA VIRUS HELICASE: MUTANT MET47THR
Descriptor:RNA HELICASE
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2W5E
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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:PUTATIVE SERINE PROTEASE, CADMIUM ION, CHLORIDE ION
Authors:Speroni, S., Rohayem, J., Nenci, S., Bonivento, D., Robel, I., Barthel, J., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2008-12-10
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution.
J.Mol.Biol., 387, 2009
2XYQ
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, CHLORIDE ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-18
Release date:2011-10-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYR
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, SODIUM ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-18
Release date:2011-10-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYV
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, SODIUM ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-19
Release date:2011-10-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
3GPG
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS
Descriptor:Non-structural protein 3
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GPO
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GPQ
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS IN COMPLEX WITH RNA
Descriptor:Non-structural protein 3, RNA (5'-R(*AP*AP*A)-3')
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GQE
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS
Descriptor:Non-structural protein 3, BICINE
Authors:Jamal, S., Malet, H., Coutard, B., Canard, B.
Deposit date:2009-03-24
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GQO
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Malet, H., Jamal, S., Coutard, B., Ferron, F., Canard, B.
Deposit date:2009-03-24
Release date:2009-07-21
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3OUO
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-15
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OV9
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION, SODIUM ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-16
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3Q3X
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CRYSTAL STRUCTURE OF THE MAIN PROTEASE (3C) FROM HUMAN ENTEROVIRUS B EV93
Descriptor:HEVB EV93 3C protease, GLYCEROL, MAGNESIUM ION
Authors:Costenaro, L., Sola, M., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2010-12-22
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3Q3Y
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COMPLEX STRUCTURE OF HEVB EV93 MAIN PROTEASE 3C WITH COMPOUND 1 (AG7404)
Descriptor:HEVB EV93 3C protease, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate, 1,2-ETHANEDIOL, ...
Authors:Costenaro, L., Kaczmarska, Z., Arnan, C., Sola, M., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2010-12-22
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3RUO
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COMPLEX STRUCTURE OF HEVB EV93 MAIN PROTEASE 3C WITH RUPINTRIVIR (AG7088)
Descriptor:HEVB EV93 3C PROTEASE, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Kaczmarska, Z., Janowski, R., Costenaro, L., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2011-05-05
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
4U4I
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MEGAVIRUS CHILENSIS SUPEROXIDE DISMUTASE
Descriptor:Cu/Zn superoxide dismutase
Authors:Lartigue, A., Claverie, J.-M., Burlat, B., Coutard, B., Abergel, C.
Deposit date:2014-07-23
Release date:2014-11-05
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The megavirus chilensis cu,zn-superoxide dismutase: the first viral structure of a typical cellular copper chaperone-independent hyperstable dimeric enzyme.
J.Virol., 89, 2015
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