Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1EE5
DownloadVisualize
BU of 1ee5 by Molmil
YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, NUCLEOPLASMIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
2FAL
DownloadVisualize
BU of 2fal by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-06-14
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
2FAM
DownloadVisualize
BU of 2fam by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
1BCU
DownloadVisualize
BU of 1bcu by Molmil
ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN
Descriptor: ALPHA-THROMBIN, HIRUGEN, PROFLAVIN
Authors:Conti, E, Rivetti, C, Wonacott, A, Brick, P.
Deposit date:1998-05-02
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
1BK6
DownloadVisualize
BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
Descriptor: KARYOPHERIN ALPHA, LARGE T ANTIGEN
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1AMU
DownloadVisualize
BU of 1amu by Molmil
PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE
Descriptor: ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ...
Authors:Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P.
Deposit date:1997-06-18
Release date:1998-07-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
1BK5
DownloadVisualize
BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
Descriptor: COBALT (II) ION, KARYOPHERIN ALPHA
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1EE4
DownloadVisualize
BU of 1ee4 by Molmil
CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1LCI
DownloadVisualize
BU of 1lci by Molmil
FIREFLY LUCIFERASE
Descriptor: LUCIFERASE
Authors:Conti, E, Franks, N.P, Brick, P.
Deposit date:1996-06-01
Release date:1997-03-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
2BR2
DownloadVisualize
BU of 2br2 by Molmil
RNase PH core of the archaeal exosome
Descriptor: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2
Authors:lorentzen, E, Fribourg, S, Conti, E.
Deposit date:2005-04-30
Release date:2005-06-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits.
Nat.Struct.Mol.Biol., 12, 2005
5OKZ
DownloadVisualize
BU of 5okz by Molmil
Crystal Strucrure of the Mpp6 Exosome complex
Descriptor: CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ...
Authors:Falk, S, Ebert, J, Conti, E.
Deposit date:2017-07-26
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.200039 Å)
Cite:Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Cell Rep, 20, 2017
2C37
DownloadVisualize
BU of 2c37 by Molmil
RNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA
Descriptor: 5-O-phosphono-beta-D-ribofuranose, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-04
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
5AIE
DownloadVisualize
BU of 5aie by Molmil
Not4 ring domain in complex with Ubc4
Descriptor: GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION
Authors:Bhaskar, V, Basquin, J, Conti, E.
Deposit date:2015-02-12
Release date:2015-04-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
6SYT
DownloadVisualize
BU of 6syt by Molmil
Structure of the SMG1-SMG8-SMG9 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Gat, Y, Schuller, J.M, Conti, E.
Deposit date:2019-10-01
Release date:2019-12-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex.
Nat.Struct.Mol.Biol., 26, 2019
4UM2
DownloadVisualize
BU of 4um2 by Molmil
Crystal structure of the TPR domain of SMG6
Descriptor: GLYCEROL, TELOMERASE-BINDING PROTEIN EST1A
Authors:Chakrabarti, S, Bonneau, F, Schuessler, S, Eppinger, E, Conti, E.
Deposit date:2014-05-14
Release date:2014-07-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6.
Nucleic Acids Res., 42, 2014
1W3B
DownloadVisualize
BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
7AQO
DownloadVisualize
BU of 7aqo by Molmil
yeast THO-Sub2 complex dimer
Descriptor: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
Authors:Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
Deposit date:2020-10-22
Release date:2020-12-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
7APX
DownloadVisualize
BU of 7apx by Molmil
yeast THO-Sub2 complex
Descriptor: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ...
Authors:Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
Deposit date:2020-10-20
Release date:2020-12-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
5JEA
DownloadVisualize
BU of 5jea by Molmil
Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ...
Authors:Kowalinski, E, Ebert, J, Stegmann, E, Conti, E.
Deposit date:2016-04-18
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex.
Mol.Cell, 63, 2016
5OOQ
DownloadVisualize
BU of 5ooq by Molmil
Structure of the Mtr4 Nop53 Complex
Descriptor: ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION
Authors:Falk, S, Basquin, J, Conti, E.
Deposit date:2017-08-08
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
1BA3
DownloadVisualize
BU of 1ba3 by Molmil
FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Descriptor: LUCIFERASE, TRIBROMOMETHANE
Authors:Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P.
Deposit date:1998-04-21
Release date:1998-11-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
3N89
DownloadVisualize
BU of 3n89 by Molmil
KH domains
Descriptor: Defective in germ line development protein 3, isoform a
Authors:Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
6YVH
DownloadVisualize
BU of 6yvh by Molmil
CWC22-CWC27-EIF4A3 Complex
Descriptor: Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog
Authors:Basquin, J, Busetto, V, LeHir, H, Conti, E.
Deposit date:2020-04-28
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
7Z52
DownloadVisualize
BU of 7z52 by Molmil
Human NEXT dimer - focused reconstruction of the single MTR4
Descriptor: Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ...
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-07
Release date:2022-06-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
7Z4Z
DownloadVisualize
BU of 7z4z by Molmil
Human NEXT dimer - focused reconstruction of the dimerization module
Descriptor: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-06
Release date:2022-06-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022

225399

PDB entries from 2024-09-25

PDB statisticsPDBj update infoContact PDBjnumon