1BCU

ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN

Summary for 1BCU
DescriptorALPHA-THROMBIN, HIRUGEN, PROFLAVIN, ... (5 entities in total)
Functional Keywordscomplex (serine protease inhibitor), hydrolase, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHirudo medicinalis (medicinal leech)
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Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P01050
Total number of polymer chains3
Total formula weight35634.58
Authors
Conti, E.,Rivetti, C.,Wonacott, A.,Brick, P. (deposition date: 1998-05-02, release date: 1998-10-14, Last modification date: 2018-04-18)
Primary citationBrick, P.,Conti, E.,Rivetti, C.,Wonacott, A.
X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425:229-233, 1998
PubMed: 9559654
DOI: 110.1016/S0014-5793(98)00235-X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-23