4LBM | |
4LBN | |
4LBO | |
2NMN | |
2NMO | |
2NN8 | | CRYSTAL STRUCTURE OF HUMAN GALECTIN-3 CARBOHYDRATE-RECOGNITION DOMAIN WITH LACTOSE BOUND, AT 1.35 ANGSTROM RESOLUTION | | Descriptor: | Galectin-3, BETA-LACTOSE, ALPHA-LACTOSE, ... | | Authors: | Blanchard, H., Collins, P.M. | | Deposit date: | 2006-10-24 | | Release date: | 2007-03-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols.
Acta Crystallogr.,Sect.D, 63, 2007
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3T1L | |
3T1M | |
3T2T | |
4JC1 | |
6EW3 | | CRYSTAL STRUCTURE OF THE METALLO-BETA-LACTAMASE VIM-2 WITH ML302F | | Descriptor: | Metallo-beta-lactamase VIM-2, ZINC ION, FORMIC ACID, ... | | Authors: | Collins, P.M., Brem, J., McDonough, M.A., van Berkel, S.S., von Delft, F., Schofield, C.J. | | Deposit date: | 2017-11-03 | | Release date: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
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6F83 | | CRYSTAL STRUCTURE OF HUMAN GALECTIN-1 IN COMPLEX WITH THIENYL-1,2, 3-TRIAZOLYL THIODIGALACTOSIDE INHIBITOR | | Descriptor: | Galectin-1, 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside | | Authors: | Collins, P.M., Blanchard, H. | | Deposit date: | 2017-12-12 | | Release date: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands
To be published
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3OY8 | |
3OYW | |
5ORL | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., Vrzal, L., Birchall, K., Arnold, L.H., Mpamhanga, C., Coombs, P.J., Burgess, S.G., Richards, M.W., Winter, A., Veverka, V., von Delft, F., Merritt, A., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORN | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORO | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORP | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORR | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORS | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORT | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORV | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORW | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORX | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORY | | CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH AN ALLOSTERICALLY BINDING FRAGMENT | | Descriptor: | Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | McIntyre, P.J., Collins, P.M., von Delft, F., Bayliss, R. | | Deposit date: | 2017-08-16 | | Release date: | 2017-11-01 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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