6EW3
Crystal structure of the metallo-beta-lactamase VIM-2 with ML302F
Summary for 6EW3
Entry DOI | 10.2210/pdb6ew3/pdb |
Related | 4PVO |
Descriptor | Metallo-beta-lactamase VIM-2, ZINC ION, FORMIC ACID, ... (7 entities in total) |
Functional Keywords | metal binding, hydrolase, antibiotic resistance, xchem, complex |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 51024.69 |
Authors | Collins, P.M.,Brem, J.,McDonough, M.A.,van Berkel, S.S.,von Delft, F.,Schofield, C.J. (deposition date: 2017-11-03, release date: 2018-10-03, Last modification date: 2024-01-17) |
Primary citation | Zhang, D.,Markoulides, M.S.,Stepanovs, D.,Rydzik, A.M.,El-Hussein, A.,Bon, C.,Kamps, J.J.A.G.,Umland, K.D.,Collins, P.M.,Cahill, S.T.,Wang, D.Y.,von Delft, F.,Brem, J.,McDonough, M.A.,Schofield, C.J. Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Bioorg. Med. Chem., 26:2928-2936, 2018 Cited by PubMed: 29655609DOI: 10.1016/j.bmc.2018.02.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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