1MHW
 
 | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides | Descriptor: | 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L | Authors: | Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O. | Deposit date: | 2002-08-21 | Release date: | 2002-12-11 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides J.Med.Chem., 45, 2002
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2GIO
 
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2GIP
 
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5UZ9
 
 | Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex | Descriptor: | Anti-CRISPR protein 30, Anti-CRISPR protein Acr30-35, CRISPR RNA (60-MER), ... | Authors: | Chowdhury, S, Carter, J, Rollins, M.F, Jackson, R.N, Hoffmann, C, Nosaka, L, Bondy-Denomy, J, Maxwell, K.L, Davidson, A.R, Fischer, E.R, Lander, G.C, Wiedenheft, B. | Deposit date: | 2017-02-25 | Release date: | 2017-04-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell, 169, 2017
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8U71
 
 | Structure of sea urchin SLC9C1 at pH 8 in Na+ | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-14 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | SLC9C1 at pH 8 in presence of K+ To Be Published
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8U7K
 
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8U7R
 
 | WT sea urchin SLC9C1 at pH 6 in presence of K+ | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-15 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | WT sea urchin SLC9C1 at pH 6 in presence of K+ To Be Published
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8U73
 
 | R399A sea urchin SLC9C1 pH 8 in Na+ | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-14 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of R399A mutant of sea urchin SLC9C1 at pH 8 in Na+ To Be Published
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8U7D
 
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8U75
 
 | R399A mutant of sea urchin SLC9C1 at pH 6 in Na+ - Compressed state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-14 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | R399A mutant of sea urchin SLC9C1 at pH 6 in presence of Na+ - Compressed Form To Be Published
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8U7S
 
 | SLC9C1 at pH 6 in presence of Na+ | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-15 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | SLC9C1 at pH 6 in presence of Na+ To Be Published
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8U7O
 
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8U6Z
 
 | SLC9C1 at pH 8 in presence of K+ | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Digitonin, Sperm-specific sodium proton exchanger | Authors: | Chowdhury, S, Pal, K. | Deposit date: | 2023-09-14 | Release date: | 2025-03-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | SLC9C1 at pH 8 in presence of K+ To Be Published
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8U7P
 
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6NE0
 
 | Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14) | Descriptor: | CRISPR RNA (60-MER), CRISPR target DNA (44-MER), CRISPR-associated endonuclease Cas6/Csy4, ... | Authors: | Chowdhury, S, Rollins, M.F, Carter, J, Golden, S.M, Miettinen, H.M, Santiago-Frangos, A, Faith, D, Lawrence, M.C, Wiedenheft, B, Lander, G.C. | Deposit date: | 2018-12-15 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Mol. Cell, 74, 2019
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4UC0
 
 | Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis | Descriptor: | HYPOXANTHINE, Purine nucleoside phosphorylase | Authors: | Cameron, S.A, Sampathkumar, P, Ramagopal, U.A, Attonito, J, Ahmed, M, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Schramm, V.L, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-08-13 | Release date: | 2014-10-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis To be published
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3SJN
 
 | Crystal structure of enolase Spea_3858 (target EFI-500646) from Shewanella pealeana with magnesium bound | Descriptor: | GLYCEROL, MAGNESIUM ION, Mandelate racemase/muconate lactonizing protein, ... | Authors: | Patskovsky, Y, Kim, J, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-06-21 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Enolase Spea_3858 from Shewanella Pealeana To be Published
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7EZJ
 
 | Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements. | Descriptor: | 12-mer DNA, Tumor protein p73, ZINC ION | Authors: | Koley, T, Roy Chowdhury, S, Kumar, M, Kaur, P, Singh, T.P, Viadiu, H, Ethayathulla, A.S. | Deposit date: | 2021-06-01 | Release date: | 2022-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies. Int.J.Biol.Macromol., 206, 2022
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4WK5
 
 | Crystal structure of a Isoprenoid Synthase family member from Thermotoga neapolitana DSM 4359, target EFI-509458 | Descriptor: | Geranyltranstransferase | Authors: | Toro, R, Bhosle, R, Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Poulter, C.D, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a Isoprenoid Synthase family member from Thermotoga neapolitana DSM 4359, target EFI-509458 To be published
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6W18
 
 | Structure of S. pombe Arp2/3 complex in inactive state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1, ... | Authors: | Shaaban, M, Nolen, B.J, Chowdhury, S. | Deposit date: | 2020-03-03 | Release date: | 2020-08-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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6W17
 
 | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Shaaban, M, Nolen, B.J, Chowdhury, S. | Deposit date: | 2020-03-03 | Release date: | 2020-08-12 | Last modified: | 2025-04-02 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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3M0E
 
 | Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family) | Authors: | Chen, B, Sysoeva, T.A, Chowdhury, S, Rusu, M, Birmanns, S, Guo, L, Hanson, J, Yang, H, Nixon, B.T. | Deposit date: | 2010-03-02 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Engagement of Arginine Finger to ATP Triggers Large Conformational Changes in NtrC1 AAA+ ATPase for Remodeling Bacterial RNA Polymerase. Structure, 18, 2010
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9BWS
 
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9BSN
 
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9BYI
 
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