Author results

4GY5
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CRYSTAL STRUCTURE OF THE TANDEM TUDOR DOMAIN AND PLANT HOMEODOMAIN OF UHRF1 WITH HISTONE H3K9ME3
Descriptor:E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
Authors:Cheng, J., Yang, Y., Fang, J., Xiao, J., Zhu, T., Chen, F., Wang, P., Xu, Y.
Deposit date:2012-09-05
Release date:2012-11-14
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
4YOC
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CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX
Descriptor:DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
Authors:Cheng, J., Yang, H., Fang, J., Gong, R., Wang, P., Li, Z., Xu, Y.
Deposit date:2015-03-11
Release date:2015-05-27
Method:X-RAY DIFFRACTION (2.916 Å)
Cite:Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
5C56
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CRYSTAL STRUCTURE OF USP7/HAUSP IN COMPLEX WITH ICP0
Descriptor:Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Cheng, J., Li, Z., Gong, R., Fang, J., Yang, Y., Sun, C., Yang, H., Xu, Y.
Deposit date:2015-06-19
Release date:2015-07-08
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.685 Å)
Cite:Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015
6RXT
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE A
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXU
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE B1
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXV
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE B2
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXX
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE C, POLY-ALA
Descriptor:Periodic tryptophan protein 2-like protein, Utp3, Utp6, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXY
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE A
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXZ
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME (KRE33-NOC4) FROM CHAETOMIUM THERMOPHILUM, STATE B
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Griesel, S., Berninghausen, O., Beckmann, R., Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
2ZR1
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AGGLUTININ FROM ABRUS PRECATORIUS
Descriptor:Agglutinin-1 chain A, Agglutinin-1 chain B, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Cheng, J., Lu, T.H., Liu, C.L., Lin, J.Y.
Deposit date:2008-08-22
Release date:2009-08-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A biophysical elucidation for less toxicity of Agglutinin than Abrin-a from the Seeds of Abrus Precatorius in consequence of crystal structure
J.Biomed.Sci., 17, 2010
4F2B
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MODULATION OF S.AUREUS PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MEMBRANE BINDING
Descriptor:1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE
Authors:Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-05-07
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity.
J.Biol.Chem., 287, 2012
4F2T
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MODULATION OF S.AUREUS PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MEMBRANE BINDING.
Descriptor:1-phosphatidylinositol phosphodiesterase, ACETATE ION
Authors:Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-05-08
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity.
J.Biol.Chem., 287, 2012
4F2U
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STRUCTURE OF THE N254Y/H258Y DOUBLE MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM S.AUREUS
Descriptor:1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
Authors:Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-05-08
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity.
J.Biol.Chem., 287, 2012
5B5H
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HYDROPHOBIC ICE-BINDING SITE CONFER HYPERACTIVITY ON ANTIFREEZE PROTEIN FROM A SNOW MOLD FUNGUS
Descriptor:Antifreeze protein, SULFATE ION, SODIUM ION
Authors:Cheng, J., Hanada, Y., Miura, A., Tsuda, S., Kondo, H.
Deposit date:2016-05-06
Release date:2016-09-28
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:Hydrophobic ice-binding sites confer hyperactivity of an antifreeze protein from a snow mold fungus.
Biochem.J., 473, 2016
5HDI
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STRUCTURAL CHARACTERIZATION OF CYP144A1, A MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450
Descriptor:Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chenge, J., Driscoll, M.D., McLean, K.J., Munro, A.W., Leys, D.
Deposit date:2016-01-05
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
5OQL
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CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME FROM CHAETOMIUM THERMOPHILUM
Descriptor:Periodic tryptophan protein 2-like protein, Utp2, Utp3, ...
Authors:Cheng, J., Kellner, N., Berninghausen, O., Hurt, E., Beckmann, R.
Deposit date:2017-08-12
Release date:2017-10-11
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
4I8Y
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STRUCTURE OF THE UNLIGANDED N254Y/H258Y MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM S. AUREUS
Descriptor:1-phosphatidylinositol phosphodiesterase, CHLORIDE ION, ACETATE ION
Authors:Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-12-04
Release date:2013-04-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
4I90
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STRUCTURE OF THE N254Y/H258Y MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM S. AUREUS BOUND TO CHOLINE
Descriptor:1-phosphatidylinositol phosphodiesterase, ACETATE ION, CHOLINE ION, ...
Authors:Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-12-04
Release date:2013-04-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
4I9J
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STRUCTURE OF THE N254Y/H258Y MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM S. AUREUS BOUND TO DIC4PC
Descriptor:1-phosphatidylinositol phosphodiesterase, ACETATE ION, (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide
Authors:Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-12-05
Release date:2013-04-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
4I9M
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STRUCTURE OF THE N254Y/H258Y MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM STAPHYLOCOCCUS AUREUS BOUND TO HEPES
Descriptor:1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
Authors:Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-12-05
Release date:2013-04-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
4I9T
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STRUCTURE OF THE H258Y MUTANT OF THE PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM STAPHYLOCOCCUS AUREUS
Descriptor:1-phosphatidylinositol phosphodiesterase, SULFATE ION, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ...
Authors:Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.
Deposit date:2012-12-05
Release date:2013-04-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
5ZR1
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SACCHAROMYCES CEREVISIAE ORIGIN RECOGNITION COMPLEX BOUND TO A 72-BP ORIGIN DNA CONTAINING ACS AND B1 ELEMENT
Descriptor:Origin recognition complex subunit 1, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ...
Authors:Li, N., Lam, W.H., Zhai, Y., Cheng, J., Cheng, E., Zhao, Y., Gao, N., Tye, B.K.
Deposit date:2018-04-21
Release date:2018-07-11
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
5IAY
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NMR STRUCTURE OF UHRF1 TANDEM TUDOR DOMAINS IN A COMPLEX WITH SPACER PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Spacer
Authors:Fang, J., Cheng, J., Wang, J., Zhang, Q., Liu, M., Gong, R., Wang, P., Zhang, X., Feng, Y., Lan, W., Gong, Z., Tang, C., Wong, J., Yang, H., Cao, C., Xu, Y.
Deposit date:2016-02-22
Release date:2016-04-20
Method:SOLUTION NMR
Cite:Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
4HBK
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STRUCTURE OF THE ALDOSE REDUCTASE FROM SCHISTOSOMA JAPONICUM
Descriptor:Aldo-keto reductase family 1, member B4 (Aldose reductase)
Authors:Liu, J., Cheng, J., Zhang, X., Yang, Z., Hu, W., Xu, Y.
Deposit date:2012-09-28
Release date:2013-06-26
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.
Parasit Vectors, 6, 2013
4NM6
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CRYSTAL STRUCTURE OF TET2-DNA COMPLEX
Descriptor:Methylcytosine dioxygenase TET2, 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', ZINC ION, ...
Authors:Hu, L., Li, Z., Cheng, J., Rao, Q., Gong, W., Liu, M., Wang, P., Xu, Y.
Deposit date:2013-11-14
Release date:2013-12-18
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.026 Å)
Cite:Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
167327
PDB entries from 2020-08-05