Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state B1

This is a large structure.

Summary for 6RXU

EMDB information10052
DescriptorPeriodic tryptophan protein 2-like protein, Utp2, Utp3, ... (64 entities in total)
Functional Keywordsribosome, ribosome biogenesis, rrna
Biological sourceChaetomium thermophilum
Total number of polymer chains66
Total molecular weight4503119.51
Cheng, J.,Kellner, N.,Griesel, S.,Berninghausen, O.,Beckmann, R.,Hurt, E. (deposition date: 2019-06-10, release date: 2019-08-14, Last modification date: 2019-10-02)
Primary citation
Cheng, J.,Bassler, J.,Fischer, P.,Lau, B.,Kellner, N.,Kunze, R.,Griesel, S.,Kallas, M.,Berninghausen, O.,Strauss, D.,Beckmann, R.,Hurt, E.
Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75:1256-1269.e7, 2019
PubMed: 31378463 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.06.032
MImport into Mendeley
Experimental method

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 0.1% 2.8% 0.49MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-10-21