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5YAM
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SOLUTION STRUCTURE OF MICE MET-CCL5/RANTES
Descriptor:C-C motif chemokine 5
Authors:Chen, Y.-C., Chen, S.-P., Lee, Y.-Z., Sue, S.-C.
Deposit date:2017-09-01
Release date:2018-09-05
Method:SOLUTION NMR
Cite:Solution structure of mice Met-CCL5/RANTES
To Be Published
1MR6
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SOLUTION STRUCTURE OF GAMMA-BUNGAROTOXIN:IMPLICATION FOR THE ROLE OF THE RESIDUES ADJACENT TO RGD IN INTEGRIN BINDING
Descriptor:neurotoxin
Authors:Chuang, W.-J., Shiu, J.-H., Chen, C.-Y., Chen, Y.-C., Chang, L.-S.
Deposit date:2002-09-18
Release date:2004-05-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of gamma-bungarotoxin: The functional significance of amino acid residues flanking the RGD motif in integrin binding
Proteins, 57, 2004
2WIA
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN APO FORM
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, MAGNESIUM ION
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
2WIB
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GDP BINDING STATE
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, GUANOSINE-5'-DIPHOSPHATE
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
2WIC
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CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE
Descriptor:FERROUS IRON TRANSPORT PROTEIN B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Hung, K.-W., Chang, Y.-W., Chen, J.-H., Chen, Y.-C., Sun, Y.-J., Hsiao, C.-D., Huang, T.-H.
Deposit date:2009-05-09
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob.
J.Struct.Biol., 170, 2010
3MRU
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CRYSTAL STRUCTURE OF AMINOACYLHISTIDINE DIPEPTIDASE FROM VIBRIO ALGINOLYTICUS
Descriptor:Aminoacyl-histidine dipeptidase, ZINC ION
Authors:Chang, C.-Y., Hsieh, Y.-C., Wu, T.-K., Chen, C.-J.
Deposit date:2010-04-29
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure and mutational analysis of aminoacylhistidine dipeptidase from vibrio alginolyticus reveal a new architecture of M20 metallopeptidases
J.Biol.Chem., 285, 2010
2PJI
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SOLUTION STRUCTURE OF RHODOSTOMIN P48A MUTANT
Descriptor:Rhodostoxin-disintegrin rhodostomin
Authors:Chuang, W.-J., Liu, Y.-C., Shiu, J.-H.
Deposit date:2007-04-16
Release date:2007-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Dynamic Properties of the RGD Motif of Disintegrin Modulate its Recognition to Integrin a5b1
To be Published
1BC4
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THE SOLUTION STRUCTURE OF A CYTOTOXIC RIBONUCLEASE FROM THE OOCYTES OF RANA CATESBEIANA (BULLFROG), NMR, 15 STRUCTURES
Descriptor:RIBONUCLEASE
Authors:Chang, C.-F., Chen, C., Chen, Y.-C., Hom, K., Huang, R.-F., Huang, T.
Deposit date:1998-05-05
Release date:1998-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog).
J.Mol.Biol., 283, 1998
5L6O
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EPHB3 KINASE DOMAIN COVALENTLY BOUND TO AN IRREVERSIBLE INHIBITOR (COMPOUND 3)
Descriptor:Ephrin type-B receptor 3, 1-(4-phenylazanylquinazolin-7-yl)ethanone, 1,4-DIETHYLENE DIOXIDE
Authors:Schimpl, M., Overman, R., Kung, A., Chen, Y.-C., Ni, F., Zhu, J., Turner, M., Molina, H., Zhang, C.
Deposit date:2016-05-30
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
5L6P
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EPHB3 KINASE DOMAIN COVALENTLY BOUND TO AN IRREVERSIBLE INHIBITOR (COMPOUND 6)
Descriptor:Ephrin type-B receptor 3, ~{N}-(4-phenylazanylquinazolin-7-yl)ethanamide, 1,4-DIETHYLENE DIOXIDE
Authors:Schimpl, M., Overman, R., Kung, A., Chen, Y.-C., Ni, F., Zhu, J., Turner, M., Molina, H., Zhang, C.
Deposit date:2016-05-30
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
5MJA
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KINASE DOMAIN OF HUMAN EPHB1 BOUND TO A QUINAZOLINE-BASED INHIBITOR
Descriptor:Ephrin type-B receptor 1, 2-chloranyl-~{N}-[4-[(2-chloranyl-5-oxidanyl-phenyl)amino]quinazolin-7-yl]ethanamide, SULFATE ION
Authors:Kung, A., Schimpl, M., Chen, Y.-C., Overman, R.C., Zhang, C.
Deposit date:2016-11-30
Release date:2017-05-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases.
ACS Chem. Biol., 12, 2017
5MJB
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KINASE DOMAIN OF HUMAN EPHB1, G703C MUTANT, COVALENTLY BOUND TO A QUINAZOLINE-BASED INHIBITOR
Descriptor:Ephrin type-B receptor 1, 2-chloranyl-~{N}-[4-[(2-chloranyl-5-oxidanyl-phenyl)amino]quinazolin-7-yl]ethanamide, SULFATE ION
Authors:Kung, A., Schimpl, M., Chen, Y.-C., Overman, R.C., Zhang, C.
Deposit date:2016-11-30
Release date:2017-05-17
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases.
ACS Chem. Biol., 12, 2017
6CAD
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CRYSTAL STRUCTURE OF RAF KINASE DOMAIN BOUND TO THE INHIBITOR 2A
Descriptor:Serine/threonine-protein kinase B-raf, 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Authors:Maisonneuve, P., Kurinov, I., Assadieskandar, A., Yu, C., Liu, X., Chen, Y.-C., Prakash, G.K.S., Zhang, C., SIcheri, F.
Deposit date:2018-01-30
Release date:2018-02-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Effects of rigidity on the selectivity of protein kinase inhibitors.
Eur J Med Chem, 146, 2018