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2LZ3
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SOLUTION NMR STRUCTURE OF TRANSMEMBRANE DOMAIN OF AMYLOID PRECURSOR PROTEIN WT
分子名称:Amyloid beta A4 protein
著者Chen, W., Wang, C.
登録日2012-09-23
公開日2013-10-02
最終更新日2016-04-27
実験手法SOLUTION NMR
主引用文献Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site.
Nat Commun, 5, 2014
2LZ4
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SOLUTION NMR STRUCTURE OF TRANSMEMBRANE DOMAIN OF AMYLOID PRECURSOR PROTEIN V44M
分子名称:Amyloid beta A4 protein
著者Chen, W., Wang, C.
登録日2012-09-23
公開日2013-10-02
最終更新日2016-04-27
実験手法SOLUTION NMR
主引用文献Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site.
Nat Commun, 5, 2014
3DSH
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CRYSTAL STRUCTURE OF DIMERIC INTERFERON REGULATORY FACTOR 5 (IRF-5) TRANSACTIVATION DOMAIN
分子名称:Interferon regulatory factor 5
著者Chen, W., Lam, S.S., Srinath, H., Jiang, Z., Correia, J.J., Schiffer, C., Fitzgerald, K.A., Lin, K., Royer Jr., W.E.
登録日2008-07-12
公開日2008-10-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Nat.Struct.Mol.Biol., 15, 2008
3GBL
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CRYSTAL STRUCTURE OF GRASS CARP BETA2-MICROGLOBULIN
分子名称:Beta2-microglobulin
著者Chen, W., Gao, F., Xia, C., Gao, G.F.
登録日2009-02-20
公開日2010-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of grass carp Beta2-microglobulin
To be Published
5HZQ
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CRYSTAL STRUCTURE OF CELLULAR RETINOIC ACID BINDING PROTEIN 2 (CRABP2)-ARYL FLUOROSULFATE COVALENT CONJUGATE
分子名称:Cellular retinoic acid-binding protein 2, 4'-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy][1,1'-biphenyl]-4-yl sulfurofluoridate, GLYCEROL
著者Chen, W., Mortenson, D.E., Wilson, I.A., Kelly, J.W.
登録日2016-02-02
公開日2016-06-01
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.
J.Am.Chem.Soc., 138, 2016
5Y29
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1
分子名称:insect group II chitinase, N-ACETYL-D-GLUCOSAMINE
著者Chen, W., Qu, M.B., Zhou, Y., Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y2A
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 2
分子名称:insect group II chitinase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
著者Chen, W., Qu, M.B., Zhou, Y., Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y2B
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1 IN COMPLEX WITH HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7
分子名称:insect group II chitinase, N-ACETYL-D-GLUCOSAMINE
著者Chen, W., Qu, M.B., Zhou, Y., Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y2C
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 2 E2180L MUTANT IN COMPLEX WITH PENTA-N-ACETYLCHITOOCTAOSE (NAG)5
分子名称:insect group II chitinase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
著者Chen, W., Qu, M.B., Zhou, Y., Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
6JAV
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1 IN COMPLEX WITH A PIPERIDINE-THIENOPYRIDINE DERIVATIVE
分子名称:Group II chitinase, 2-{[(4-chlorophenyl)methyl]sulfanyl}-7-methyl-N-(prop-2-en-1-yl)-7,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine, N-ACETYL-D-GLUCOSAMINE
著者Chen, W., Zhou, Y., Yang, Q.
登録日2019-01-25
公開日2019-05-15
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.437 Å)
主引用文献Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
6JAW
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1 IN COMPLEX WITH A NAPTHALIMIDE DERIVATIVE
分子名称:Group II chitinase, 2-[3-(morpholin-4-yl)propyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, N-ACETYL-D-GLUCOSAMINE
著者Chen, W., Zhou, Y., Yang, Q.
登録日2019-01-25
公開日2019-05-15
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
6JAX
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1 IN COMPLEX WITH CHITOOCTAOSE [(GLCN)8]
分子名称:Group II chitinase, N-ACETYL-D-GLUCOSAMINE, D-GLUCOSAMINE
著者Chen, W., Zhou, Y., Yang, Q.
登録日2019-01-25
公開日2019-05-15
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
6JAY
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CRYSTAL STRUCTURE OF OSTRINIA FURNACALIS GROUP II CHITINASE CATALYTIC DOMAIN 1 IN COMPLEX WITH A DIPYRIDO-PYRIMIDINE DERIVATIVE
分子名称:Group II chitinase, N-ACETYL-D-GLUCOSAMINE, 2-amino-1-[(furan-2-yl)methyl]-5-oxo-3-({[(2S)-oxolan-2-yl]methyl}carbamoyl)-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-1-ium
著者Chen, W., Zhou, Y., Yang, Q.
登録日2019-01-25
公開日2019-05-15
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
4NPL
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CRYSTAL STRUCTURE OF ZEBRAFISH ALKBH5 IN COMPLEX WITH ALPHA-KETOGLUTARATE
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION, 2-OXOGLUTARIC ACID
著者He, C., Chen, W., Zhang, L.
登録日2013-11-21
公開日2014-02-19
最終更新日2014-04-02
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Febs Lett., 588, 2014
4NPM
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CRYSTAL STRUCTURE OF ZEBRAFISH ALKBH5 IN COMPLEX WITH SUCCINIC ACID
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION, SUCCINIC ACID
著者He, C., Chen, W., Zhang, L.
登録日2013-11-21
公開日2014-02-19
最終更新日2014-04-02
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Febs Lett., 588, 2014
2M9E
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 5-1
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
登録日2013-06-07
公開日2013-06-26
最終更新日2013-07-17
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9F
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 5-1G
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N-ACETYL-D-GLUCOSAMINE
著者Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
登録日2013-06-07
公開日2013-06-26
最終更新日2013-07-17
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9I
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN VARIANT 6-1
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
登録日2013-06-10
公開日2013-06-26
最終更新日2013-07-17
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9J
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 6-1G
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N-ACETYL-D-GLUCOSAMINE
著者Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
登録日2013-06-10
公開日2013-06-26
最終更新日2013-07-17
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
3R1K
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CRYSTAL STRUCTURE OF ACETYLTRANSFERASE EIS FROM MYCOBACTERIUM TUBERCULOSIS H37RV IN COMPLEX WITH COA AND AN ACETAMIDE MOIETY
分子名称:Enhanced intracellular survival protein, COENZYME A, ACETAMIDE
著者Biswas, T., Chen, W., Garneau-Tsodikova, S., Tsodikov, O.V.
登録日2011-03-10
公開日2011-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.
Proc.Natl.Acad.Sci.USA, 108, 2011
5YCO
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COMPLEX STRUCTURE OF PCNA WITH UHRF2
分子名称:Proliferating cell nuclear antigen, E3 ubiquitin-protein ligase UHRF2, GLYCEROL, ...
著者Wu, M., Chen, W., Hang, T., Wang, C., Zhang, X., Zang, J.
登録日2017-09-07
公開日2017-11-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
3VTR
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CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 E328A COMPLEXED WITH TMG-CHITOTRIOMYCIN
分子名称:N-acetylglucosaminidase, 2-deoxy-2-(trimethylammonio)-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose, N-ACETYL-D-GLUCOSAMINE
著者Liu, T., Zhou, Y., Chen, L., Chen, W., Liu, L., Shen, X., Yang, Q.
登録日2012-06-02
公開日2013-01-16
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into cellulolytic and chitinolytic enzymes revealing crucial residues of insect beta-N-acetyl-D-hexosaminidase
Plos One, 7, 2012
6NHW
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 - DIMER OF TRIMER
分子名称:Tumor necrosis factor receptor superfamily member 10B
著者Chou, J.J., Pan, L., Fu, Q., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H.
登録日2018-12-24
公開日2019-02-27
最終更新日2019-03-20
実験手法SOLUTION NMR
主引用文献Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NHY
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 MUTANT (G217Y) - TRIMER ONLY
分子名称:Tumor necrosis factor receptor superfamily member 10B
著者Chou, J.J., Pan, L., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H., Liu, Z.
登録日2018-12-24
公開日2019-02-27
最終更新日2019-03-20
実験手法SOLUTION NMR
主引用文献Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
1S9W
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CRYSTAL STRUCTURE ANALYSIS OF NY-ESO-1 EPITOPE, SLLMWITQC, IN COMPLEX WITH HLA-A2
分子名称:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
著者Webb, A.I., Dunstone, M.A., Chen, W., Aguilar, M.I., Chen, Q., Chang, L., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Rossjohn, J., Purcell, A.W.
登録日2004-02-05
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004