Author results

7JX3
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MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:Light chain of Fab domain of monoclonal antibody S309, Heavy chain of Fab domain of monoclonal antibody S309, Light chain of Fab domain of monoclonal antibody S2H14, ...
Authors:Snell, G., Czudnochowski, N., Rosen, L.E., Nix, J.C., Corti, D., Veesler, D., Park, Y.J., Walls, A.C., Tortorici, M.A., Cameroni, E., Pinto, D., Beltramello, M.
Deposit date:2020-08-26
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
6NB3
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MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB5
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CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB8
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CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6WPS
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STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE S309 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., De Marco, A., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
6WPT
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STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE S309 NEUTRALIZING ANTIBODY FAB FRAGMENT (OPEN STATE)
Descriptor:SARS-CoV-2 spike glycoprotein, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., De Marco, A., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
6WS6
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STRUCTURAL AND FUNCTIONAL ANALYSIS OF A POTENT SARBECOVIRUS NEUTRALIZING ANTIBODY
Descriptor:S309 antigen-binding (Fab) fragment, heavy chain, light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., Marco, A.D., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Telenti, A., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-30
Release date:2020-05-27
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
5OMZ
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SOLUTION STRUCTURE OF DOMAIN III (DIII)OF ZIKA VIRUS ENVELOPE PROTEIN
Descriptor:Envelope Protein
Authors:Zerbe, O., Bardelli, M.
Deposit date:2017-08-02
Release date:2017-10-04
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
5Y0A
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CRYO-EM STRUCTURE OF ZIKA VIRUS COMPLEXED WITH FAB OF ZKA190 AT PH 8.0 AND 37 CELSIUS DEGREE
Descriptor:protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
Authors:Wang, J.Q., Lok, S.M.
Deposit date:2017-07-15
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (22 Å)
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
7JV2
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RECEPTOR-BINDING MOTIF AND FAB VARIABLE DOMAINS)
Descriptor:S2H13 Fab heavy chain, S2H13 Fab light chain, SARS-CoV-2 spike glycoprotein
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JV4
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY (ONE RBD OPEN)
Descriptor:SARS-CoV-2 spike glycoprotein, S2H13 Fab heavy chain, S2H13 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JV6
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY (CLOSED CONFORMATION)
Descriptor:SARS-CoV-2 spike glycoprotein, S2H13 Fab heavy chain, S2H13 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JVA
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2A4 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RECEPTOR-BINDING DOMAIN AND FAB VARIABLE DOMAINS)
Descriptor:S2A4 Fab heavy chain, S2A4 Fab light chain, SARS-CoV-2 spike glycoprotein, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JVC
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2A4 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S2A4 Fab heavy chain, S2A4 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JW0
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S304 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S304 Fab light chain, S304 Fab heavy chain, ...
Authors:Walls, A.C., Park, Y.J., Tortorici, M.A., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-24
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JXC
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MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:S2H14 antigen-binding (Fab) fragment, NONAETHYLENE GLYCOL
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-27
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JXD
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MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:S2A4 antigen-binding (Fab) fragment
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-27
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JXE
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MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:S2X35 antigen-binding (Fab) fragment
Authors:Tortorici, M.A., Park, Y.J., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-27
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7K3Q
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AN ULTRA-POTENT HUMAN NEUTRALIZING ANTIBODY LOCKS THE SARS-COV-2 SPIKE IN THE CLOSED CONFORMATION
Descriptor:Fab fragment of S2E12 monoclonal antibody, heavy chain, light chain, ...
Authors:Snell, G., Czudnochowski, N., Ng, C.
Deposit date:2020-09-12
Release date:2020-10-07
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
7K43
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2M11 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S2M11 Fab fragment (heavy chain), S2M11 Fab fragment (light chain), ...
Authors:Tortorici, M.A., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-14
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
7K45
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2E12 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RBD AND FAB VARIABLE DOMAINS)
Descriptor:S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), Spike glycoprotein, ...
Authors:Tortorici, M.A., Veesler, D.
Deposit date:2020-09-14
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
7K4N
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2E12 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:Spike glycoprotein, S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), ...
Authors:Tortorici, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-15
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
170172
PDB entries from 2020-10-21