Author results

1T24
  • Download 1t24
  • View 1t24
Molmil generated image of 1t24
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH NAD+ AND 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID
Descriptor:L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, ...
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-20
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T25
  • Download 1t25
  • View 1t25
Molmil generated image of 1t25
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND 3-HYDROXYISOXAZOLE-4-CARBOXYLIC ACID
Descriptor:L-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-HYDROXYISOXAZOLE-4-CARBOXYLIC ACID, ...
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-20
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T26
  • Download 1t26
  • View 1t26
Molmil generated image of 1t26
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID
Descriptor:L-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-20
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2C
  • Download 1t2c
  • View 1t2c
Molmil generated image of 1t2c
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH NADH
Descriptor:L-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-21
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2D
  • Download 1t2d
  • View 1t2d
Molmil generated image of 1t2d
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH NAD+ AND OXALATE
Descriptor:L-lactate dehydrogenase, OXALATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-21
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2E
  • Download 1t2e
  • View 1t2e
Molmil generated image of 1t2e
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE S245A, A327P MUTANT COMPLEXED WITH NADH AND OXAMATE
Descriptor:L-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, ...
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-21
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2F
  • Download 1t2f
  • View 1t2f
Molmil generated image of 1t2f
HUMAN B LACTATE DEHYDROGENASE COMPLEXED WITH NAD+ AND 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID
Descriptor:L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID
Authors:Cameron, A., Read, J., Tranter, R., Winter, V.J., Sessions, R.B., Brady, R.L., Vivas, L., Easton, A., Kendrick, H., Croft, S.L., Barros, D., Lavandera, J.L., Martin, J.J., Risco, F., Garcia-Ochoa, S., Gamo, F.J., Sanz, L., Leon, L., Ruiz, J.R., Gabarro, R., Mallo, A., De Las Heras, F.G.
Deposit date:2004-04-21
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
2BPM
  • Download 2bpm
  • View 2bpm
Molmil generated image of 2bpm
STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, (2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE, ...
Authors:Cameron, A., Fogliatto, G., Pevarello, P., Brasca, M.G., Orsini, P., Traquandi, G., Longo, A., Nesi, M., Orzi, F., Piutti, C., Sansonna, P., Varasi, M., Vulpetti, A., Roletto, F., Alzani, R., Ciomei, M., Albanese, C., Pastori, W., Marsiglio, A., Pesenti, E., Fiorentini, F., Bischoff, J.R., Mercurio, C.
Deposit date:2005-04-21
Release date:2005-12-08
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3-Aminopyrazole Inhibitors of Cdk2-Cyclin a as Antitumor Agents. 2. Lead Optimization
J.Med.Chem., 48, 2005
2C4G
  • Download 2c4g
  • View 2c4g
Molmil generated image of 2c4g
STRUCTURE OF CDK2-CYCLIN A WITH PHA-533514
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, SULFATE ION, ...
Authors:Cameron, A., Fogliatto, G., Pevarello, P., Fancelli, D., Vulpetti, A., Amici, R., Villa, M., Pittala, V., Ciomei, M., Mercurio, C., Bischoff, J.R., Roletto, F., Varasi, M., Brasca, M.G.
Deposit date:2005-10-19
Release date:2005-11-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:3-Amino-1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: A New Class of Cdk2 Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
1VYW
  • Download 1vyw
  • View 1vyw
Molmil generated image of 1vyw
STRUCTURE OF CDK2/CYCLIN A WITH PNU-292137
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, SULFATE ION, ...
Authors:Pevarello, P., Brasca, M.G., Amici, R., Orsini, P., Traquandi, G., Corti, L., Piutti, C., Sansonna, P., Villa, M., Pierce, B.S., Pulici, M., Giordano, P., Martina, K., Fritzen, E.L., Nugent, R.A., Casale, E., Cameron, A., Ciomei, M., Roletto, F., Isacchi, A., Fogliatto, G., Pesenti, E., Pastori, W., Marsiglio, A., Leach, K.L., Clare, P.M., Fiorentini, F., Varasi, M., Vulpetti, A., Warpehoski, M.A.
Deposit date:2004-05-07
Release date:2004-06-10
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:3-Aminopyrazole Inhibitors of Cdk2/Cyclin a as Antitumor Agents. Part 1. Lead Finding
J.Med.Chem., 47, 2004
1VYZ
  • Download 1vyz
  • View 1vyz
Molmil generated image of 1vyz
STRUCTURE OF CDK2 COMPLEXED WITH PNU-181227
Descriptor:CELL DIVISION PROTEIN KINASE 2, N-(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)BENZAMIDE
Authors:Pevarello, P., Brasca, M.G., Amici, R., Orsini, P., Traquandi, G., Corti, L., Piutti, C., Sansonna, P., Villa, M., Pierce, B.S., Pulici, M., Giordano, G., Martina, K., Lfritzen, E., Nugent, R.A., Casale, E., Cameron, A., Ciomei, M., Roletto, F., Isacchi, A., Fogliatto, G., Pesenti, E., Pastori, W., Marsiglio, W., Leach, K.L., Clare, P.M., Fiorentini, F., Varasi, M., Vulpetti, A., Warpehoski, M.A.
Deposit date:2004-05-07
Release date:2004-06-17
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:3-Aminopyrazole Inhibitors of Cdk2/Cyclin a as Antitumor Agents. 1. Lead Finding
J.Med.Chem., 47, 2004
2BKZ
  • Download 2bkz
  • View 2bkz
Molmil generated image of 2bkz
STRUCTURE OF CDK2-CYCLIN A WITH PHA-404611
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, 1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE, ...
Authors:DAlessio, R., Bargiottia, A., Metz, S., Brasca, M.G., Cameron, A., Ermoli, A., Marsiglio, A., Polucci, P., Roletto, F., Tibolla, M., Vazquez, M.L., Vulpetti, A., Pevarello, P.
Deposit date:2005-02-23
Release date:2006-03-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Benzodipyrazoles: A New Class of Potent Cdk2 Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
1U4O
  • Download 1u4o
  • View 1u4o
Molmil generated image of 1u4o
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 2,6-NAPHTHALENEDICARBOXYLIC ACID
Descriptor:L-lactate dehydrogenase, 2,6-DICARBOXYNAPHTHALENE, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Conners, R., Cameron, A., Read, J., Schambach, F., Sessions, R.B., Brady, R.L.
Deposit date:2004-07-26
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U4S
  • Download 1u4s
  • View 1u4s
Molmil generated image of 1u4s
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 2,6-NAPHTHALENEDISULPHONIC ACID
Descriptor:L-lactate dehydrogenase, NAPHTHALENE-2,6-DISULFONIC ACID
Authors:Conners, R., Cameron, A., Read, J., Schambach, F., Sessions, R.B., Brady, R.L.
Deposit date:2004-07-26
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U5A
  • Download 1u5a
  • View 1u5a
Molmil generated image of 1u5a
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 3,5-DIHYDROXY-2-NAPHTHOIC ACID
Descriptor:L-lactate dehydrogenase, 3,7-DIHYDROXY-2-NAPHTHOIC ACID
Authors:Conners, R., Cameron, A., Read, J., Schambach, F., Sessions, R.B., Brady, R.L.
Deposit date:2004-07-27
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U5C
  • Download 1u5c
  • View 1u5c
Molmil generated image of 1u5c
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID AND NAD+
Descriptor:L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3,7-DIHYDROXY-2-NAPHTHOIC ACID
Authors:Conners, R., Cameron, A., Read, J., Schambach, F., Sessions, R.B., Brady, R.L.
Deposit date:2004-07-27
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1XIV
  • Download 1xiv
  • View 1xiv
Molmil generated image of 1xiv
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 2-({4-CHLORO-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL
Descriptor:L-lactate dehydrogenase, 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL
Authors:Conners, R., Cameron, A., Read, J.A., Schambach, F., Sessions, R.B., Brady, R.L.
Deposit date:2004-09-22
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase
MOL.BIOCHEM.PARASITOL., 142, 2005
1P8J
  • Download 1p8j
  • View 1p8j
Molmil generated image of 1p8j
CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor:Furin precursor, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Henrich, S., Cameron, A., Bourenkov, G.P., Kiefersauer, R., Huber, R., Lindberg, I., Bode, W., Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
5A16
  • Download 5a16
  • View 5a16
Molmil generated image of 5a16
CRYSTAL STRUCTURE OF FAB4201 RAISED AGAINST HUMAN ERYTHROCYTE ANION EXCHANGER 1
Descriptor:FAB4201 HEAVY CHAIN
Authors:Arakawa, T., Kobayashi-Yugiri, T., Alguel, Y., Weyand, S., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015
1BNI
  • Download 1bni
  • View 1bni
Molmil generated image of 1bni
BARNASE WILDTYPE STRUCTURE AT PH 6.0
Descriptor:BARNASE
Authors:Cameron, A., Henrick, K., Fersht, A.R., Dodson, G., Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNJ
  • Download 1bnj
  • View 1bnj
Molmil generated image of 1bnj
BARNASE WILDTYPE STRUCTURE AT PH 9.0
Descriptor:BARNASE
Authors:Cameron, A., Henrick, K., Fersht, A.R., Dodson, G., Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
2WIP
  • Download 2wip
  • View 2wip
Molmil generated image of 2wip
STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1-METHYL-4,5-DIHYDRO- 1H-PYRAZOLO[4,3-H] QUINAZOLINE-3-CARBOXYLIC ACID
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid, ...
Authors:Brasca, M.G., Amboldi, N., Ballinari, D., Cameron, A.D., Casale, E., Cervi, G., Colombo, M., Colotta, F., Croci, V., Dalessio, R., Fiorentini, F., Isacchi, A., Mercurio, C., Moretti, W., Panzeri, A., Pastori, W., Pevarello, P., Quartieri, F., Roletto, F., Traquandi, G., Vianello, P., Vulpetti, A., Ciomei, M.
Deposit date:2009-05-14
Release date:2009-07-28
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification of N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide (Pha-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor.
J.Med.Chem., 52, 2009
2BMC
  • Download 2bmc
  • View 2bmc
Molmil generated image of 2bmc
AURORA-2 T287D T288D COMPLEXED WITH PHA-680632
Descriptor:SERINE THREONINE-PROTEIN KINASE 6, (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE
Authors:Cameron, A.D., Izzo, G., Sagliano, A., Rusconi, L., Storici, P., Fancelli, D., Berta, D., Bindi, S., Catana, C., Forte, B., Giordano, P., Mantegani, S., Meroni, M., Moll, J., Pittala, V., Severino, D., Tonani, R., Varasi, M., Vulpetti, A., Vianello, P.
Deposit date:2005-03-11
Release date:2005-03-17
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
2J4Z
  • Download 2j4z
  • View 2j4z
Molmil generated image of 2j4z
STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626
Descriptor:SERINE THREONINE-PROTEIN KINASE 6, 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC
Authors:Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
Deposit date:2006-09-08
Release date:2006-11-06
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
J. Med. Chem., 49, 2006
5BZ2
  • Download 5bz2
  • View 5bz2
Molmil generated image of 5bz2
CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION
Descriptor:Na(+)/H(+) antiporter
Authors:Coincon, M., Uzdavinys, P., Cameron, A., Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
<12>