Author results

4V7C
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA STRUCTURE)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-20
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V7D
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA*EF-G STRUCTURE)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L1, ...
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-21
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
3J6X
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 5 DEGREE ROTATION (CLASS II)
Descriptor:25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J6Y
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 2 DEGREE ROTATION (CLASS I)
Descriptor:25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J77
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS II - ROTATED RIBOSOME WITH 1 TRNA)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, ...
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3J78
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS I - NON-ROTATED RIBOSOME WITH 2 TRNAS)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, ...
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
5KPS
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STRUCTURE OF RELA BOUND TO RIBOSOME IN ABSENCE OF A/R TRNA (STRUCTURE I)
Descriptor:GTP pyrophosphokinase, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPV
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE II)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPW
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE III)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPX
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE IV)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
3J3I
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PENICILLIUM CHRYSOGENUM VIRUS (PCV) CAPSID STRUCTURE
Descriptor:Capsid protein
Authors:Luque, D., Gomez-Blanco, J., Garriga, D., Brilot, A., Gonzalez, J.M., Havens, W.H., Carrascosa, J.L., Trus, B.L., Verdaguer, N., Grigorieff, N., Ghabrial, S.A., Caston, J.R.
Deposit date:2013-03-08
Release date:2014-05-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage.
Proc.Natl.Acad.Sci.USA, 111, 2014
5J0N
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LAMBDA EXCISION HJ INTERMEDIATE
Descriptor:attP(-117 to +79), attB(-21) to attP(+117), attB(-19 to +21), ...
Authors:Van Duyne, G., Grigorieff, N., Landy, A.
Deposit date:2016-03-28
Release date:2017-02-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
Elife, 5, 2016
6PC5
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E. COLI 50S RIBOSOME BOUND TO COMPOUNDS 46 AND VS1
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-16
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PC6
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 47
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-16
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PC7
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 46
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-16
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PC8
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 40Q
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-16
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PCH
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 21
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-17
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PCQ
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E. COLI 50S RIBOSOME BOUND TO VM2
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-18
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PCR
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 40O
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-18
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PCS
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 40E
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-18
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6PCT
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E. COLI 50S RIBOSOME BOUND TO COMPOUND 41Q
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2019-06-18
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
6WYV
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E. COLI 50S RIBOSOME BOUND TO COMPOUNDS 47 AND VS1
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.
Deposit date:2020-05-13
Release date:2020-06-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586, 2020
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171916
PDB entries from 2020-12-02