Author results

1PNJ
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE SH3 DOMAIN OF THE P85ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Booker, G.W., Gout, I., Downing, A.K., Driscoll, P.C., Boyd, J., Waterfield, M.D., Campbell, I.D.
Deposit date:1993-07-19
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase.
Cell(Cambridge,Mass.), 73, 1993
2PNA
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STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN
Authors:Booker, G.W., Breeze, A.L., Downing, A.K., Panayotou, G., Gout, I., Waterfield, M.D., Campbell, I.D.
Deposit date:1992-06-30
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.
Nature, 358, 1992
2PNB
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STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN
Authors:Booker, G.W., Breeze, A.L., Downing, A.K., Panayotou, G., Gout, I., Waterfield, M.D., Campbell, I.D.
Deposit date:1992-06-30
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.
Nature, 358, 1992
2PNI
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE SH3 DOMAIN OF THE P85ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Booker, G.W., Gout, I., Downing, A.K., Driscoll, P.C., Boyd, J., Waterfield, M.D., Campbell, I.D.
Deposit date:1993-07-19
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase.
Cell(Cambridge,Mass.), 73, 1993
1C8P
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NMR STRUCTURE OF THE LIGAND BINDING DOMAIN OF THE COMMON BETA-CHAIN IN THE GM-CSF, IL-3 AND IL-5 RECEPTORS
Descriptor:CYTOKINE RECEPTOR COMMON BETA CHAIN
Authors:Mulhern, T.D., D'Andrea, R.J., Gaunt, C., Vandeleur, L., Vadas, M.A., Lopez, A.F., Booker, G.W., Bagley, C.J.
Deposit date:1999-10-05
Release date:2000-06-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5.
J.Mol.Biol., 297, 2000
1GL5
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NMR STRUCTURE OF THE SH3 DOMAIN FROM THE TEC PROTEIN TYROSINE KINASE
Descriptor:TYROSINE-PROTEIN KINASE TEC
Authors:Mulhern, T.D., Pursglove, S.E., Booker, G.W.
Deposit date:2001-08-28
Release date:2001-11-28
Last modified:2018-02-28
Method:SOLUTION NMR
Cite:The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
J. Biol. Chem., 277, 2002
1WLX
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SOLUTION STRUCTURE OF THE THIRD SPECTRIN REPEAT OF ALPHA-ACTININ-4
Descriptor:Alpha-actinin 4
Authors:Kowalski, K., Merkel, A.L., Booker, G.W.
Deposit date:2004-06-30
Release date:2005-08-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the third spectrin repeat of alpha-actinin-4
To be Published
1WMV
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SOLUTION STRUCTURE OF THE SECOND WW DOMAIN OF WWOX
Descriptor:WW domain containing oxidoreductase
Authors:Kowalski, K., Merkel, A.L., Colella, A., Richards, R.I., Booker, G.W.
Deposit date:2004-07-21
Release date:2005-08-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the second WW domain of WWOX
To be Published
1WR3
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SOLUTION STRUCTURE OF THE FIRST WW DOMAIN OF NEDD4-2
Descriptor:ubiquitin-protein ligase Nedd4-2
Authors:Kowalski, K., Merkel, A.L., Booker, G.W.
Deposit date:2004-10-11
Release date:2005-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of WW domains of Nedd4-2
To be Published
1WR4
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SOLUTION STRUCTURE OF THE SECOND WW DOMAIN OF NEDD4-2
Descriptor:ubiquitin-protein ligase Nedd4-2
Authors:Kowalski, K., Merkel, A.L., Booker, G.W.
Deposit date:2004-10-11
Release date:2005-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of the WW domains of Nedd4-2
To be Published
1WR7
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SOLUTION STRUCTURE OF THE THIRD WW DOMAIN OF NEDD4-2
Descriptor:Nedd4-2
Authors:Kowalski, K., Merkel, A.L., Booker, G.W.
Deposit date:2004-10-13
Release date:2005-10-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of the WW domains of Nedd4-2
To be Published
4WOP
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NUCLEOTIDE TRIPHOSPHATE PROMISCUITY IN MYCOBACTERIUM TUBERCULOSIS DETHIOBIOTIN SYNTHETASE
Descriptor:ATP-dependent dethiobiotin synthetase BioD, CYTIDINE-5'-TRIPHOSPHATE, SULFATE ION
Authors:Salaemae, W., Yap, M.Y., Wegener, K.L., Booker, G.W., Wilce, M.C.J., Polyak, S.W.
Deposit date:2014-10-16
Release date:2015-04-08
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase.
Tuberculosis (Edinb), 95, 2015
6CZD
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DETHIOBIOTIN SYNTHETASE IN COMPLEX WITH ADENOSINE DIPHOSPHATE
Descriptor:ATP-dependent dethiobiotin synthetase BioD, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.
Deposit date:2018-04-09
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase.
Acta Crystallogr D Struct Biol, 74, 2018
4DQ2
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STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH BIOTINOL-5'-AMP
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE
Authors:Wilce, M., Yap, M., Pendini, N., Soares de Costa, T., Polyak, S., Tieu, W., Booker, G., Wallace, J.
Deposit date:2012-02-14
Release date:2012-04-18
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3RKW
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, BIOTINYL-5-AMP
Authors:Wilce, M.C.J., Pendini, N.R., Yap, M.Y.
Deposit date:2011-04-18
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
To be published
3RKX
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase
Authors:Wilce, M.C.J.
Deposit date:2011-04-18
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
TO BE PUBLISHED
3RKY
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, BIOTIN
Authors:Wilce, M.C.J.
Deposit date:2011-04-18
Release date:2012-04-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.232 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
To be Published
3V7C
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CYSTAL STRUCTURE OF SABPL IN COMPLEX WITH INHIBITOR
Descriptor:Biotin ligase, 5'-deoxy-2',3'-O-(1-methylethylidene)-5'-(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)adenosine
Authors:Yap, M.Y., Pendini, N.R.
Deposit date:2011-12-20
Release date:2012-04-18
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3V7R
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH INHIBITOR
Descriptor:Biotin ligase, (3aS,4S,6aR)-4-(5-{1-[4-(6-amino-9H-purin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
Authors:Yap, M.Y., Pendini, N.R.
Deposit date:2011-12-21
Release date:2012-12-26
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3V7S
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH INHIBITOR 0364
Descriptor:Biotin ligase, 5-methyl-3-[4-(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one
Authors:Yap, M.Y., Pendini, N.R.
Deposit date:2011-12-21
Release date:2012-04-25
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3V8J
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin ligase
Authors:Pendini, N.R., Yap, M.Y.
Deposit date:2011-12-23
Release date:2012-12-26
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3V8K
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH BIOTIN
Descriptor:Biotin ligase, BIOTIN
Authors:Yap, M.Y., Pendini, N.R.
Deposit date:2011-12-23
Release date:2012-12-26
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
3V8L
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH BIOTINYL-5'-AMP
Descriptor:Biotin ligase, BIOTINYL-5-AMP
Authors:Yap, M.Y.
Deposit date:2011-12-23
Release date:2012-12-26
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Selective inhibition of biotin protein ligase from Staphylococcus aureus.
J.Biol.Chem., 287, 2012
6APW
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH INHIBITOR
Descriptor:Bifunctional ligase/repressor BirA, 4-[(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)methyl]benzoic acid
Authors:Cini, D.A., Wilce, M.C.J.
Deposit date:2017-08-18
Release date:2018-02-07
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ACS Infect Dis, 4, 2018
6AQQ
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH INHIBITOR
Descriptor:Bifunctional ligase/repressor BirA, (3aS,4S,6aR)-4-(5-{1-[(3-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl}pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
Authors:Cini, D.A., Wilce, M.C.J.
Deposit date:2017-08-21
Release date:2018-02-07
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ACS Infect Dis, 4, 2018
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