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6CVF

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine diphosphate

Summary for 6CVF
Entry DOI10.2210/pdb6cvf/pdb
Related3FGN 3FMF 3FMI 3FPA 4WOP 6CVE 6CVU 6CVV 6CZB 6CZC 6CZD 6CZE
DescriptorATP-dependent dethiobiotin synthetase BioD, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsenzyme, synthetase, nucleotide triphosphate binding, transferase
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains4
Total formula weight95581.27
Authors
Thompson, A.P.,Bruning, J.B.,Wegener, K.L.,Polyak, S.W. (deposition date: 2018-03-28, release date: 2018-11-21, Last modification date: 2024-03-13)
Primary citationThompson, A.P.,Salaemae, W.,Pederick, J.L.,Abell, A.D.,Booker, G.W.,Bruning, J.B.,Polyak, S.W.
Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes
Acs Catalysis, 8(11):10774-10783, 2018
Cited by
DOI: 10.1021/acscatal.8b03475
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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