3FGN

Crystal structure of dethiobiotin synthetase in Mycobacterium tuberculosis

Summary for 3FGN

Entry DOI	10.2210/pdb3fgn/pdb
Descriptor	Dethiobiotin synthetase (2 entities in total)
Functional Keywords	dethiobiotin synthetase, biotin biosynthesis, biod, atp-binding, ligase, magnesium, nucleotide-binding
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (By similarity): O06620
Total number of polymer chains	4
Total formula weight	101263.56
Authors	Dey, S.,Sacchettini, J.C. (deposition date: 2008-12-08, release date: 2009-06-30, Last modification date: 2024-02-21)
Primary citation	Dey, S.,Lane, J.M.,Lee, R.E.,Rubin, E.J.,Sacchettini, J.C. Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49:6746-6760, 2010 Cited by PubMed: 20565114 DOI: 10.1021/bi902097j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation