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3MFG
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CRYSTAL STRUCTURE OF TOXIC SHOCK SYNDROME TOXIN 1 (TSST-1) IN COMPLEX WITH THE HUMAN T CELL RECEPTOR BETA CHAIN VBETA2.1 (EP-8)
Descriptor:Toxic shock syndrome toxin-1, V_segment translation product, SULFATE ION, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2010-04-02
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8)
To be Published
3R8B
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN B IN COMPLEX WITH AN AFFINITY MATURED MOUSE TCR VBETA8.2 PROTEIN, G5-8
Descriptor:Enterotoxin type B, G5-8, CHLORIDE ION, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2011-03-23
Release date:2011-04-06
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular basis of a million-fold affinity maturation process in a protein-protein interaction.
J.Mol.Biol., 411, 2011
4Y88
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF CEACAM8
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 8, SULFATE ION, GLYCEROL, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Y89
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF CEACAM7
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 7, CHLORIDE ION
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-09-02
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the N-terminal dimerization domain of CEACAM7.
Acta Crystallogr.,Sect.F, 71, 2015
4Y8A
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF CEACAM6
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 6, ZINC ION, GLYCEROL
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YIQ
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STRUCTURE OF THE CEACAM6-CEACAM8 HETERODIMER
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 8, Carcinoembryonic antigen-related cell adhesion molecule 6, GLYCEROL, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2015-03-02
Release date:2015-10-07
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
6AVZ
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CRYSTAL STRUCTURE OF THE HOPQ-CEACAM3 WT COMPLEX
Descriptor:HopQ, Carcinoembryonic antigen-related cell adhesion molecule 3, part of HopQ loop, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW0
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CRYSTAL STRUCTURE OF CEACAM3 L44Q
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, CHLORIDE ION, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW1
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CRYSTAL STRUCTURE OF CEACAM3
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, CHLORIDE ION, ...
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW2
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CRYSTAL STRUCTURE OF THE HOPQ-CEACAM1 COMPLEX
Descriptor:Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW3
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CRYSTAL STRUCTURE OF THE HOPQ-CEACAM3 L44Q COMPLEX
Descriptor:HopQ, Carcinoembryonic antigen-related cell adhesion molecule 3
Authors:Bonsor, D.A., Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
2HQS
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CRYSTAL STRUCTURE OF TOLB/PAL COMPLEX
Descriptor:Protein tolB, Peptidoglycan-associated lipoprotein, ACETATE ION, ...
Authors:Grishkovskaya, I., Bonsor, D.A., Kleanthous, C., Dodson, E.J.
Deposit date:2006-07-19
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular mimicry enables competitive recruitment by a natively disordered protein.
J.Am.Chem.Soc., 129, 2007
2W8B
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CRYSTAL STRUCTURE OF PROCESSED TOLB IN COMPLEX WITH PAL
Descriptor:PROTEIN TOLB, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, SULFATE ION, ...
Authors:Sharma, A., Bonsor, D.A., Kleanthous, C.
Deposit date:2009-01-15
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins.
Embo J., 28, 2009
4X5U
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X-RAY CRYSTAL STRUCTURE OF CAGL AT PH 4.2
Descriptor:Cag pathogenicity island protein (Cag18)
Authors:Sundberg, E.J., Bonsor, D.A., Diederichs, K.
Deposit date:2014-12-05
Release date:2015-04-08
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Integrin Engagement by the Helical RGD Motif of the Helicobacter pylori CagL Protein Is Regulated by pH-induced Displacement of a Neighboring Helix.
J.Biol.Chem., 290, 2015
2IVZ
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STRUCTURE OF TOLB IN COMPLEX WITH A PEPTIDE OF THE COLICIN E9 T- DOMAIN
Descriptor:PROTEIN TOLB, COLICIN-E9, CALCIUM ION
Authors:Loftus, S.R., Walker, D., Mate, M.J., Bonsor, D.A., James, R., Moore, G.R., Kleanthous, C.
Deposit date:2006-06-23
Release date:2006-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9
Proc.Natl.Acad.Sci.USA, 103, 2006
3QLQ
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CRYSTAL STRUCTURE OF CONCANAVALIN A BOUND TO AN OCTA-ALPHA-MANNOSYL-OCTASILSESQUIOXANE CLUSTER
Descriptor:Concanavalin-A, CALCIUM ION, MANGANESE (II) ION, ...
Authors:Sundberg, E.J., Bonsor, D.A., Trastoy, B., Chiara, J.L.
Deposit date:2011-02-03
Release date:2012-02-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthesis and Biophysical Study of Disassembling Nano hybrid Bioconjugates with a Cubic Octasilsesquioxane Core
Adv Funct Mater, 22, 2012
5FHY
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CRYSTAL STRUCTURE OF FLID (HAP2) FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:B-type flagellar hook-associated protein 2, SODIUM ION
Authors:Postel, S., Bonsor, D., Diederichs, K., Sundberg, E.J.
Deposit date:2015-12-22
Release date:2016-10-05
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Bacterial flagellar capping proteins adopt diverse oligomeric states.
Elife, 5, 2016
6DHB
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CRYSTAL STRUCTURE OF THE HUMAN TIM-3 WITH BOUND CALCIUM
Descriptor:Hepatitis A virus cellular receptor 2, CALCIUM ION, BENZOIC ACID, ...
Authors:Gandhi, A.K., Kim, W.M., Huang, Y.H., Bonsor, D., Sundberg, E., Sun, Z.-Y., Petsko, G.A., Kuchroo, V., Blumberg, R.S.
Deposit date:2018-05-19
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3.
Sci Rep, 8, 2018
3PL6
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STRUCTURE OF AUTOIMMUNE TCR HY.1B11 IN COMPLEX WITH HLA-DQ1 AND MBP 85-99
Descriptor:MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta chain, T-cell receptor alpha chain, ...
Authors:Sethi, D.K., Wucherpfennig, K.W.
Deposit date:2010-11-13
Release date:2010-12-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
J.Exp.Med., 208, 2011
3BVG
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MANIPULATING THE COUPLED FOLDING AND BINDING PROCESS DRIVES AFFINITY MATURATION IN A PROTEIN-PROTEIN COMPLEX
Descriptor:Enterotoxin type C-3, ZINC ION
Authors:Cho, S., Eric, J.S.
Deposit date:2008-01-07
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Assessing energetic contributions to binding from a disordered region in a protein-protein interaction
Biochemistry, 49, 2010
5DRZ
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CRYSTAL STRUCTURE OF ANTI-HIV-1 ANTIBODY F240 FAB IN COMPLEX WITH GP41 PEPTIDE
Descriptor:HIV Antibody F240 Light Chain, HIV Antibody F240 Heavy Chain, Envelope glycoprotein gp160, ...
Authors:Gohain, N., Tolbert, W.D., Pazgier, M.
Deposit date:2015-09-16
Release date:2016-10-19
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240.
Sci Rep, 6, 2016
5VI4
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IL-33/ST2/IL-1RACP TERNARY COMPLEX STRUCTURE
Descriptor:Interleukin-33, Interleukin-1 receptor-like 1, Interleukin-1 receptor accessory protein, ...
Authors:Guenther, S., Sundberg, E.J.
Deposit date:2017-04-13
Release date:2017-09-27
Method:X-RAY DIFFRACTION (2.792 Å)
Cite:IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.
Immunity, 47, 2017