2IYA | | THE CRYSTAL STRUCTURE OF MACROLIDE GLYCOSYLTRANSFERASES: A BLUEPRINT FOR ANTIBIOTIC ENGINEERING | | Descriptor: | OLEANDOMYCIN GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE | | Authors: | Bolam, D.N., Roberts, S.M., Proctor, M.R., Turkenburg, J.P., Dodson, E.J., Martinez-Fleites, C., Yang, M., Davis, B.G., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2006-07-13 | | Release date: | 2007-03-27 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
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2IYF | | THE CRYSTAL STRUCTURE OF MACROLIDE GLYCOSYLTRANSFERASES: A BLUEPRINT FOR ANTIBIOTIC ENGINEERING | | Descriptor: | OLEANDOMYCIN GLYCOSYLTRANSFERASE, ERYTHROMYCIN A, URIDINE-5'-DIPHOSPHATE, ... | | Authors: | Bolam, D.N., Roberts, S.M., Proctor, M.R., Turkenburg, J.P., Dodson, E.J., Martinez-Fleites, C., Yang, M., Davis, B.G., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2006-07-17 | | Release date: | 2007-03-27 | | Last modified: | 2013-08-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
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1HEH | | C-TERMINAL XYLAN BINDING DOMAIN FROM CELLULOMONAS FIMI XYLANASE 11A | | Descriptor: | ENDO-1,4-BETA-XYLANASE D | | Authors: | Simpson, P.J., Hefang, X., Bolam, D.N., White, P., Hancock, S.M., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2000-11-22 | | Release date: | 2001-05-10 | | Last modified: | 2020-01-15 | | Method: | SOLUTION NMR | | Cite: | Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A
Biochemistry, 40, 2001
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1HEJ | | C-TERMINAL XYLAN BINDING DOMAIN FROM CELLULOMONAS FIMI XYLANASE 11A | | Descriptor: | ENDO-1,4-BETA-XYLANASE D | | Authors: | Simpson, P.J., Hefang, X., Bolam, D.N., White, P., Hancock, S.M., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2000-11-22 | | Release date: | 2001-05-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A
Biochemistry, 40, 2001
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1H6X | | THE ROLE OF CONSERVED AMINO ACIDS IN THE CLEFT OF THE C-TERMINAL FAMILY 22 CARBOHYDRATE BINDING MODULE OF CLOSTRIDIUM THERMOCELLUM XYN10B IN LIGAND BINDING | | Descriptor: | ENDO-1,4-BETA-XYLANASE Y, CALCIUM ION | | Authors: | Xie, H., Bolam, D.N., Charnock, S.J., Davies, G.J., Williamson, M.P., Simpson, P.J., Fontes, C.M.G.A., Ferreira, L.M.A., Gilbert, H.J. | | Deposit date: | 2001-06-29 | | Release date: | 2002-06-27 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Clostridium Thermocellum Xyn10B Carbohydrate-Binding Module 22-2: The Role of Conserved Amino Acids in Ligand Binding
Biochemistry, 40, 2001
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1H6Y | | THE ROLE OF CONSERVED AMINO ACIDS IN THE CLEFT OF THE C-TERMINAL FAMILY 22 CARBOHYDRATE BINDING MODULE OF CLOSTRIDIUM THERMOCELLUM XYN10B IN LIGAND BINDING | | Descriptor: | ENDO-1,4-BETA-XYLANASE Y, CALCIUM ION | | Authors: | Xie, H., Bolam, D.N., Charnock, S.J., Davies, G.J., Williamson, M.P., Simpson, P.J., Fontes, C.M.G.A., Ferreira, L.M.A., Gilbert, H.J. | | Deposit date: | 2001-06-29 | | Release date: | 2002-06-27 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Clostridium Thermocellum Xyn10B Carbohydrate-Binding Module 22-2: The Role of Conserved Amino Acids in Ligand Binding
Biochemistry, 40, 2001
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1E5B | | INTERNAL XYLAN BINDING DOMAIN FROM C. FIMI XYN10A, R262G MUTANT | | Descriptor: | XYLANASE D | | Authors: | Simpson, P.J., Hefang, X., Bolam, D.N., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2000-07-24 | | Release date: | 2001-05-25 | | Last modified: | 2018-10-24 | | Method: | SOLUTION NMR | | Cite: | The Structural Basis for the Ligand Specificity of Family 2 Carbohydrate Binding Nodules
J.Biol.Chem., 275, 2000
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1E5C | | INTERNAL XYLAN BINDING DOMAIN FROM C. FIMI XYN10A, R262G MUTANT | | Descriptor: | XYLANASE D | | Authors: | Simpson, P.J., Hefang, X., Bolam, D.N., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2000-07-24 | | Release date: | 2001-05-25 | | Last modified: | 2018-10-24 | | Method: | SOLUTION NMR | | Cite: | The Structural Basis for the Ligand Specificity of Family 2 Carbohydrate Binding Nodules
J.Biol.Chem., 275, 2000
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1GNY | | XYLAN-BINDING MODULE CBM15 | | Descriptor: | XYLANASE 10C, SODIUM ION, BETA-D-XYLOPYRANOSE | | Authors: | Szabo, S., Jamal, S., Xie, H., Charnock, S.J., Bolam, D.N., Gilbert, H.J., Davies, G.J. | | Deposit date: | 2001-10-10 | | Release date: | 2001-11-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structure of a Family 15 Carbohydrate-Binding Module in Complex with Xylopentaose: Evidence that Xylan Binds in an Approximate Three-Fold Helical Conformation
J.Biol.Chem., 276, 2001
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1J9Y | | CRYSTAL STRUCTURE OF MANNANASE 26A FROM PSEUDOMONAS CELLULOSA | | Descriptor: | MANNANASE A, ZINC ION | | Authors: | Hogg, D., Woo, E.-J., Bolam, D.N., McKie, V.A., Gilbert, H.J., Pickersgill, R.W. | | Deposit date: | 2001-05-29 | | Release date: | 2001-06-20 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of mannanase 26A from Pseudomonas cellulosa and analysis of residues involved in substrate binding
J.Biol.Chem., 276, 2001
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1V0A | | FAMILY 11 CARBOHYDRATE-BINDING MODULE OF CELLULOSOMAL CELLULASE LIC26A-CEL5E OF CLOSTRIDIUM THERMOCELLUM | | Descriptor: | ENDOGLUCANASE H, CALCIUM ION, SULFATE ION | | Authors: | Carvalho, A.L., Romao, M.J., Goyal, A., Prates, J.A.M., Pires, V.M.R., Ferreira, L.M.A., Bolam, D.N., Gilbert, H.J., Fontes, C.M.G.A. | | Deposit date: | 2004-03-25 | | Release date: | 2005-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | The Family 11 Carbohydrate-Binding Module of Clostridium Thermocellum Lic26A-Cel5E Accomodates Beta-1,4- and Beta-1,3-1,4-Mixed Linked Glucans at a Single Binding Site
J.Biol.Chem., 279, 2004
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1W8T | | CBM29-2 MUTANT K74A COMPLEXED WITH CELLULOHEXAOSE: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON CATALYTIC PROTEIN 1, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-09-28 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1W8U | | CBM29-2 MUTANT D83A COMPLEXED WITH MANNOHEXAOSE: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON CATALYTIC PROTEIN 1, BETA-D-MANNOSE | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-09-28 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1W8W | | CBM29-2 MUTANT Y46A: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON-CATALYTIC PROTEIN 1 | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-09-30 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1W8Z | | CBM29-2 MUTANT K85A: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON CATALYTIC PROTEIN 1 | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-10-01 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1W90 | | CBM29-2 MUTANT D114A: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON-CATALYTIC PROTEIN 1, SODIUM ION, 1,2-ETHANEDIOL | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-10-01 | | Release date: | 2005-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1W9F | | CBM29-2 MUTANT R112A: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES | | Descriptor: | NON CATALYTIC PROTEIN 1 | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davies, G.J., Gilbert, H.J. | | Deposit date: | 2004-10-12 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1WCU | | CBM29_1, A FAMILY 29 CARBOHYDRATE BINDING MODULE FROM PIROMYCES EQUI | | Descriptor: | NON-CATALYTIC PROTEIN 1, GLYCEROL | | Authors: | Flint, J., Bolam, D.N., Nurizzo, D., Taylor, E.J., Williamson, M.P., Walters, C., Davis, G.J., Gilbert, H.J. | | Deposit date: | 2004-11-22 | | Release date: | 2005-03-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
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1XBD | | INTERNAL XYLAN BINDING DOMAIN FROM CELLULOMONAS FIMI XYLANASE D, NMR, 5 STRUCTURES | | Descriptor: | XYLANASE D | | Authors: | Simpson, P.J., Bolam, D.N., Cooper, A., Ciruela, A., Hazlewood, G.P., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 1998-10-16 | | Release date: | 1999-07-21 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A family IIb xylan-binding domain has a similar secondary structure to a homologous family IIa cellulose-binding domain but different ligand specificity.
Structure Fold.Des., 7, 1999
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2BGO | | MANNAN BINDING MODULE FROM MAN5C | | Descriptor: | ENDO-B1,4-MANNANASE 5C | | Authors: | Tunnicliffe, R.B., Bolam, D.N., Pell, G., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2005-01-04 | | Release date: | 2005-03-09 | | Last modified: | 2020-01-15 | | Method: | SOLUTION NMR | | Cite: | Structure of a Mannan-Specific Family 35 Carbohydrate-Binding Module: Evidence for Significant Conformational Changes Upon Ligand Binding
J.Mol.Biol., 347, 2005
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2BGP | | MANNAN BINDING MODULE FROM MAN5C IN BOUND CONFORMATION | | Descriptor: | ENDO-B1,4-MANNANASE 5C | | Authors: | Tunnicliffe, R.B., Bolam, D.N., Pell, G., Gilbert, H.J., Williamson, M.P. | | Deposit date: | 2005-01-04 | | Release date: | 2005-03-09 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of a Mannan-Specific Family 35 Carbohydrate-Binding Module: Evidence for Significant Conformational Changes Upon Ligand Binding
J.Mol.Biol., 347, 2005
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2BO4 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | MANNOSYLGLYCERATE SYNTHASE, CITRATE ANION | | Authors: | Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J., Davies, G.J. | | Deposit date: | 2005-04-07 | | Release date: | 2005-06-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
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2BO6 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | MANNOSYLGLYCERATE SYNTHASE, (2R)-2,3-DIHYDROXYPROPANOIC ACID, MANGANESE (II) ION | | Authors: | Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J., Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
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2BO7 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | MANNOSYLGLYCERATE SYNTHASE, GUANOSINE-5'-DIPHOSPHATE, COBALT (II) ION | | Authors: | Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J., Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2019-01-16 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
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2BO8 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | MANNOSYLGLYCERATE SYNTHASE, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ... | | Authors: | Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J., Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2019-01-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
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