6T2P

Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

This is a non-PDB format compatible entry.

Summary for 6T2P

• Entry DOI: 10.2210/pdb6t2p/pdb
• Descriptor: Glycosyl hydrolase family 16, 1,2-ETHANEDIOL, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: human gut microbiota, mucin degradation, o-glycanases, gh16, endo beta-galactosidase, hydrolase
• Biological source: Bacteroides caccae ATCC 43185
• Total number of polymer chains: 2
• Total formula weight: 64889.00

Authors

Crouch, L.I.,Liberato, M.V.,Ubranowicz, P.A.,Basle, A.,Lamb, C.A.,Cooke, K.,Doona, M.,Needham, S.,Brady, R.R.,Berrington, J.E.,Madubic, K.,Chater, P.,Zhang, F.,Linhardt, R.J.,Spence, D.I.R.,Bolam, D.N. (deposition date: 2019-10-09, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Crouch, L.I.,Liberato, M.V.,Urbanowicz, P.A.,Basle, A.,Lamb, C.A.,Stewart, C.J.,Cooke, K.,Doona, M.,Needham, S.,Brady, R.R.,Berrington, J.E.,Madunic, K.,Wuhrer, M.,Chater, P.,Pearson, J.P.,Glowacki, R.,Martens, E.C.,Zhang, F.,Linhardt, R.J.,Spencer, D.I.R.,Bolam, D.N.; Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.; Nat Commun, 11:4017-4017, 2020; PubMed: 32782292; DOI: 10.1038/s41467-020-17847-5

Experimental method

X-RAY DIFFRACTION (2.1 Å)