6T2S

Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

This is a non-PDB format compatible entry.

Summary for 6T2S

• Entry DOI: 10.2210/pdb6t2s/pdb
• Descriptor: Glycoside hydrolase family 16 protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose (2 entities in total)
• Functional Keywords: human gut microbiota, mucin degradation, o-glycanases, gh16, endo beta-galactosidase, hydrolase
• Biological source: Bacteroides finegoldii DSM 17565
• Total number of polymer chains: 3
• Total formula weight: 83970.90

Authors

Crouch, L.I.,Liberato, M.V.,Ubranowicz, P.A.,Basle, A.,Lamb, C.A.,Cooke, K.,Doona, M.,Needham, S.,Brady, R.R.,Berrington, J.E.,Madubic, K.,Chater, P.,Zhang, F.,Linhardt, R.J.,Spence, D.I.R.,Bolam, D.N. (deposition date: 2019-10-09, release date: 2020-07-08, Last modification date: 2020-08-26)

• Primary citation: Crouch, L.I.,Liberato, M.V.,Urbanowicz, P.A.,Basle, A.,Lamb, C.A.,Stewart, C.J.,Cooke, K.,Doona, M.,Needham, S.,Brady, R.R.,Berrington, J.E.,Madunic, K.,Wuhrer, M.,Chater, P.,Pearson, J.P.,Glowacki, R.,Martens, E.C.,Zhang, F.,Linhardt, R.J.,Spencer, D.I.R.,Bolam, D.N.; Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.; Nat Commun, 11:4017-4017, 2020; PubMed: 32782292; DOI: 10.1038/s41467-020-17847-5

Experimental method

X-RAY DIFFRACTION (3.3 Å)