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5OF9
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603)
Descriptor:MORC family CW-type zinc finger protein 2, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Douse, C.H., Shamin, M., Modis, Y.
Deposit date:2017-07-10
Release date:2018-02-14
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.807 Å)
Cite:Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5OFA
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603) WITH SPINAL MUSCULAR ATROPHY MUTATION T424R
Descriptor:MORC family CW-type zinc finger protein 2, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Douse, C.H., Liu, Y., Modis, Y.
Deposit date:2017-07-10
Release date:2018-02-14
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5OFB
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603) WITH SPINAL MUSCULAR ATROPHY MUTATION S87L
Descriptor:MORC family CW-type zinc finger protein 2, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Douse, C.H., Liu, Y., Modis, Y.
Deposit date:2017-07-10
Release date:2018-02-14
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5AAY
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TBK1 RECRUITMENT TO CYTOSOL-INVADING SALMONELLA INDUCES ANTI- BACTERIAL AUTOPHAGY
Descriptor:NF-KAPPA-B ESSENTIAL MODULATOR, ZINC ION
Authors:Thurston, T.l., Allen, M.D., Ravenhill, B., Karpiyevitch, M., Bloor, S., Kaul, A., Matthews, S., Komander, D., Holden, D., Bycroft, M., Randow, F.
Deposit date:2015-07-31
Release date:2016-07-13
Last modified:2016-08-31
Method:SOLUTION NMR
Cite:Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy.
Embo J., 35, 2016
5AAZ
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TBK1 RECRUITMENT TO CYTOSOL-INVADING SALMONELLA INDUCES ANTI- BACTERIAL AUTOPHAGY
Descriptor:OPTINEURIN, ZINC ION
Authors:Thurston, T.l., Allen, M.D., Ravenhill, B., Karpiyevitch, M., Bloor, S., Kaul, A., Matthews, S., Komander, D., Holden, D., Bycroft, M., Randow, F.
Deposit date:2015-07-31
Release date:2016-07-13
Last modified:2016-08-31
Method:SOLUTION NMR
Cite:Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy.
Embo J., 35, 2016
5AAQ
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TBK1 RECRUITMENT TO CYTOSOL-INVADING SALMONELLA INDUCES ANTI- BACTERIAL AUTOPHAGY
Descriptor:CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2, ZINC ION
Authors:Thurston, T.L., Allen, M.D., Ravenhill, B., Karpiyevitch, M., Bloor, S., Kaul, A., Matthews, S., Komander, D., Holden, D., Bycroft, M., Randow, F.
Deposit date:2015-07-28
Release date:2016-07-13
Last modified:2016-08-31
Method:SOLUTION NMR
Cite:Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy.
Embo J., 35, 2016
3VVV
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SKICH DOMAIN OF NDP52
Descriptor:Calcium-binding and coiled-coil domain-containing protein 2
Authors:Akutsu, M., Muhlinen, N.V., Randow, F., Komander, D.
Deposit date:2012-07-28
Release date:2013-02-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
3VVW
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NDP52 IN COMPLEX WITH LC3C
Descriptor:Calcium-binding and coiled-coil domain-containing protein 2, Microtubule-associated proteins 1A/1B light chain 3C
Authors:Akutsu, M., Muhlinen, N.V., Randow, F., Komander, D.
Deposit date:2012-07-28
Release date:2013-02-27
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
2ZVN
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NEMO COZI DOMAIN INCOMPLEX WITH DIUBIQUITIN IN P212121 SPACE GROUP
Descriptor:UBC protein, NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
2ZVO
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NEMO COZI DOMAIN IN COMPLEX WITH DIUBIQUITIN IN C2 SPACE GROUP
Descriptor:UBC protein, NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
3F89
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NEMO COZI DOMAIN
Descriptor:NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-11
Release date:2009-03-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009