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4EOW
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BU of 4eow by Molmil
Crystal structure of a disease-associated anti-human GM-CSF autoantibody MB007
Descriptor: MB007 IgG1 Fab fragment light chain, MB007 human IgG1 Fab fragment heavy chain
Authors:Blech, M.
Deposit date:2012-04-16
Release date:2012-08-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications.
Biochem.J., 447, 2012
4G6J
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BU of 4g6j by Molmil
Crystal structure of human IL-1beta in complex with the therapeutic antibody binding fragment of canakinumab
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of canakinumab, light chain of antibody binding fragment of canakinumab
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-19
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:One traget-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta
J.Mol.Biol., 425, 2013
4G5Z
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BU of 4g5z by Molmil
Crystal structure of the therapeutical antibody fragment of canakinumab in its unbound state
Descriptor: canakinumab antibody fragment heavy chain, canakinumab antibody fragment light chain
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-18
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:One target-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta
J.Mol.Biol., 425, 2013
4G6M
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BU of 4g6m by Molmil
Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab
Descriptor: Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-19
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab
J.Mol.Biol., 425, 2013
4G6K
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BU of 4g6k by Molmil
Crystal structure of the therapeutic antibody binding fragment of gevokizumab in its unbound state
Descriptor: heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-19
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:One target-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta
J.Mol.Biol., 425, 2013
6GFE
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BU of 6gfe by Molmil
High-resolution Structure of a therapeutic full-length anti-NPRA Antibody with exceptional Conformational Diversity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Hoerer, S.
Deposit date:2018-04-30
Release date:2019-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
Biophys.J., 116, 2019

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