Author results

2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
Descriptor:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
Authors:Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-15
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
Descriptor:regulator of G-protein signalling 3 isoform 1, SULFATE ION
Authors:Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-11-28
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2GJS
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THE CRYSTAL STRUCTURE OF HUMAN RRAD IN COMPLEX WITH GDP
Descriptor:GTP-binding protein RAD, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Turnbull, A.P., Yang, X., Soundararajan, M., Schoch, G., Debreczeni, J., Elkins, J.M., Gileadi, C., Berridge, G., Pantic, N., Burgess, N., Smee, C.E.A., Bray, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-03-31
Release date:2006-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human RRAD in complex with GDP
To be Published
2I6L
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CRYSTAL STRUCTURE OF HUMAN MITOGEN ACTIVATED PROTEIN KINASE 6 (MAPK6)
Descriptor:Mitogen-activated protein kinase 6
Authors:Filippakopoulos, P., Turnbull, A.P., Savitsky, P., Fedorov, O., Berridge, G., Das, S., Elkins, J., Soundararajan, M., Yang, X.W., Doyle, D., Papagrigoriou, E., Pike, A.C.W., Bunkonczi, G., Ugochukwu, E., Debreczeni, J., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2006-08-29
Release date:2006-09-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Human Mitogen Activated Protein Kinase 6
To be Published
2JC6
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE 1D
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
Authors:Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Bhatia, C., Shrestha, L., Salah, E., Smee, C., Colebrook, S., Berridge, G., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Pike, A.C.W., von Delft, F., Knapp, S., Sundstrom, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.
Deposit date:2006-12-19
Release date:2007-02-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
Descriptor:Ezrin-radixin-moesin-binding phosphoprotein 50
Authors:Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-26
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2PQ5
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CRYSTAL STRUCTURE OF DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 (DUSP13)
Descriptor:Dual specificity protein phosphatase 13
Authors:Ugochukwu, E., Salah, E., Savitsky, P., Barr, A., Pantic, N., Niesen, F., Burgess-Brown, N., Berridge, G., Bunkoczi, G., Uppenberg, J., Pike, A.C.W., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-05-01
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Dual specificity protein phosphatase 13 (DUSP13).
To be Published
2UXW
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CRYSTAL STRUCTURE OF HUMAN VERY LONG CHAIN ACYL-COA DEHYDROGENASE (ACADVL)
Descriptor:VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Pike, A.C.W., Hozjan, V., Smee, C., Berridge, G., Burgess, N., Salah, E., Bunkoczi, G., Uppenberg, J., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
Deposit date:2007-03-30
Release date:2007-05-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
To be Published
2UYY
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STRUCTURE OF THE CYTOKINE-LIKE NUCLEAR FACTOR N-PAC
Descriptor:N-PAC PROTEIN, POTASSIUM ION, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
Authors:Tickle, J., Pilka, E.S., Bunkoczi, G., Berridge, G., Smee, C., Kavanagh, K.L., Hozjan, V., Niesen, F.H., Papagrigoriou, E., Pike, A.C.W., Turnbull, A., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., von Delft, F., Oppermann, U.
Deposit date:2007-04-20
Release date:2007-07-03
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structure of the Cytokine-Like Nuclear Factor N-Pac
To be Published
2UZP
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN PROTEIN KINASE C GAMMA.
Descriptor:PROTEIN KINASE C GAMMA TYPE, PYRIDOXAL-5'-PHOSPHATE, COBALT (II) ION, ...
Authors:Pike, A.C.W., Amos, A., Johansson, C., Sobott, F., Savitsky, P., Berridge, G., Fedorov, O., Umeano, C., Gorrec, F., Bunkoczi, G., Debreczeni, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
Deposit date:2007-04-30
Release date:2007-05-29
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
3B76
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CRYSTAL STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMAN LIGAND-OF-NUMB PROTEIN-X (LNX1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE FROM THE COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR
Descriptor:E3 ubiquitin-protein ligase LNX, SODIUM ION, 1,2-ETHANEDIOL
Authors:Ugochukwu, E., Burgess-Brown, N., Berridge, G., Elkins, J., Bunkoczi, G., Pike, A.C.W., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Gileadi, O., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2007-10-30
Release date:2007-11-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor.
To be Published
4B87
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CRYSTAL STRUCTURE OF HUMAN DNA CROSS-LINK REPAIR 1A
Descriptor:DNA CROSS-LINK REPAIR 1A PROTEIN, ZINC ION, 1,2-ETHANEDIOL
Authors:Allerston, C.K., Berridge, G., Carpenter, E.P., Kochan, G., Krojer, T., Mahajan, P., Vollmar, M., Yue, W.W., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Gileadi, O.
Deposit date:2012-08-24
Release date:2012-11-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal Structure of Human DNA Cross-Link Repair 1A
To be Published
2FCF
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THE CRYSTAL STRUCTURE OF THE 7TH PDZ DOMAIN OF MPDZ (MUPP-1)
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-12
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FNE
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THE CRYSTAL STRUCTURE OF THE 13TH PDZ DOMAIN OF MPDZ
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2HE4
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2) INTERACTING WITH A MODE 1 PDZ BINDING MOTIF
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, 1,2-ETHANEDIOL
Authors:Papagrigoriou, E., Elkins, J.M., Berridge, G., Gileady, O., Colebrook, S., Gileadi, C., Salah, E., Savitsky, P., Pantic, N., Gorrec, F., Bunkoczi, G., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2I1N
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CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF HUMAN DLG3
Descriptor:Discs, large homolog 3, SODIUM ION
Authors:Turnbull, A.P., Phillips, C., Bunkoczi, G., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Gorrec, F., Umeano, C., Elkins, J., Berridge, G., Savitsky, P., Gileadi, O., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-08-14
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2IWO
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12TH PDZ DOMAIN OF MULTIPLE PDZ DOMAIN PROTEIN MPDZ (CASP TARGET)
Descriptor:MULTIPLE PDZ DOMAIN PROTEIN
Authors:Elkins, J.M., Yang, X., Gileadi, C., Schoch, G., Johansson, C., Savitsky, P., Berridge, G., Smee, C.E.A., Turnbull, A., Pike, A., Papagrigoriou, E., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.A.
Deposit date:2006-07-03
Release date:2006-07-26
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
2IWP
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12TH PDZ DOMAIN OF MULTIPLE PDZ DOMAIN PROTEIN MPDZ (CASP TARGET)
Descriptor:MULTIPLE PDZ DOMAIN PROTEIN
Authors:Elkins, J.M., Yang, X., Gileadi, C., Schoch, G., Johansson, C., Savitsky, P., Berridge, G., Smee, C.E.A., Turnbull, A., Pike, A., Papagrigoriou, E., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.A.
Deposit date:2006-07-03
Release date:2006-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extension.
Protein Sci., 16, 2007
1YB5
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CRYSTAL STRUCTURE OF HUMAN ZETA-CRYSTALLIN WITH BOUND NADP
Descriptor:Quinone oxidoreductase, ACETATE ION, CHLORIDE ION, ...
Authors:Debreczeni, J., Berridge, G., Kavanagh, K., Colbrook, S., Bray, J., Williams, L., Oppermann, U., Sundstrom, M., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)
Deposit date:2004-12-20
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of human Zeta-Crystallin at 1.85A
To be Published
2AW5
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CRYSTAL STRUCTURE OF A HUMAN MALIC ENZYME
Descriptor:NADP-dependent malic enzyme
Authors:Papagrigoriou, E., Berridge, G., Smee, C., Bray, J., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)
Deposit date:2005-08-31
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a human malic enzyme
To be published
2BYG
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2ND PDZ DOMAIN OF DISCS LARGE HOMOLOGUE 2
Descriptor:CHANNEL ASSOCIATED PROTEIN OF SYNAPSE-110
Authors:Elkins, J.M., Schoch, G.A., Smee, C.E.A., Berridge, G., Salah, E., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2005-08-01
Release date:2005-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
2F6Q
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THE CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL DELTA3, DELTA2 ENOYL COA ISOMERASE (PECI)
Descriptor:Peroxisomal 3,2-trans-enoyl-CoA isomerase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Turnbull, A., Lukacik, P., Shafqat, N., Smee, C., Berridge, G., Guo, K., von Delft, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Gileadi, O., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-11-29
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)
To be Published
2GZV
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THE CYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN PICK1
Descriptor:PRKCA-binding protein
Authors:Debreczeni, J.E., Elkins, J.M., Yang, X., Berridge, G., Bray, J., Colebrook, S., Smee, C., Savitsky, P., Gileadi, O., Turnbull, A., von Delft, F., Doyle, D.A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-07-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2H5G
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE SYNTHETASE
Descriptor:Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION
Authors:Papagrigoriou, E., Shafqat, N., Turnbull, A.P., Berridge, G., Hozjan, V., Kavanagh, K., Gileadi, O., Smee, C., Bray, J., Gorrec, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-05-26
Release date:2006-06-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human pyrroline-5-carboxylate synthetase
To be published
2HE2
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CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN DISCS LARGE HOMOLOGUE 2, DLG2
Descriptor:Discs large homolog 2
Authors:Turnbull, A.P., Phillips, C., Berridge, G., Savitsky, P., Smee, C.E.A., Papagrigoriou, E., Debreczeni, J., Gorrec, F., Elkins, J.M., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007