Author results

3J7H
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STRUCTURE OF BETA-GALACTOSIDASE AT 3.2-A RESOLUTION OBTAINED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Beta-galactosidase, MAGNESIUM ION
Authors:Bartesaghi, A., Matthies, D., Banerjee, S., Merk, A., Subramaniam, S.
Deposit date:2014-06-30
Release date:2014-07-30
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CC8
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PRE-FUSION STRUCTURE OF TRIMERIC HIV-1 ENVELOPE GLYCOPROTEIN DETERMINED BY CRYO-ELECTRON MICROSCOPY
Descriptor:GP41, GP120, MONOCLONAL ANTIBODY VRC03 FAB HEAVY CHAIN, ...
Authors:Bartesaghi, A., Merk, A., Borgnia, M.J., Milne, J.L.S., Subramaniam, S.
Deposit date:2013-10-18
Release date:2013-10-30
Last modified:2018-01-10
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy.
Nat.Struct.Mol.Biol., 20, 2013
5A1A
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2.2 A RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE IN COMPLEX WITH A CELL-PERMEANT INHIBITOR
Descriptor:BETA-GALACTOSIDASE, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ...
Authors:Bartesaghi, A., Merk, A., Banerjee, S., Matthies, D., Wu, X., Milne, J., Subramaniam, S.
Deposit date:2015-04-29
Release date:2015-05-06
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
2YNJ
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GROEL AT SUB-NANOMETER RESOLUTION BY CONSTRAINED SINGLE PARTICLE TOMOGRAPHY
Descriptor:60 KDA CHAPERONIN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, THALLIUM (I) ION, ...
Authors:Bartesaghi, A., Lecumberry, F., Sapiro, G., Subramaniam, S.
Deposit date:2012-10-15
Release date:2012-12-12
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography
Structure, 20, 2012
6CVM
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ATOMIC RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE
Descriptor:Beta-galactosidase, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ...
Authors:Subramaniam, S., Bartesaghi, A., Banerjee, S., Zhu, X., Milne, J.L.S.
Deposit date:2018-03-28
Release date:2018-05-30
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Atomic Resolution Cryo-EM Structure of beta-Galactosidase.
Structure, 26, 2018
3JCZ
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STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-27
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD0
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
5FTJ
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO UPCDC30245 INHIBITOR
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE, 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTK
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ADP
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTL
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTM
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTN
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CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION III)
Descriptor:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
Deposit date:2016-01-14
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5K0Z
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CRYO-EM STRUCTURE OF LACTATE DEHYDROGENASE (LDH) IN INHIBITOR-BOUND STATE
Descriptor:L-lactate dehydrogenase B chain
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K10
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CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1)
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K11
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CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1) IN INHIBITOR-BOUND STATE
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K12
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CRYO-EM STRUCTURE OF GLUTAMATE DEHYDROGENASE AT 1.8 A RESOLUTION
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (1.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
6B44
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND TARGET DSDNA
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF1
Descriptor:CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF2
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B48
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF10
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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