3J7H | | STRUCTURE OF BETA-GALACTOSIDASE AT 3.2-A RESOLUTION OBTAINED BY CRYO-ELECTRON MICROSCOPY | | Descriptor: | Beta-galactosidase, MAGNESIUM ION | | Authors: | Bartesaghi, A., Matthies, D., Banerjee, S., Merk, A., Subramaniam, S. | | Deposit date: | 2014-06-30 | | Release date: | 2014-07-30 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CC8 | | PRE-FUSION STRUCTURE OF TRIMERIC HIV-1 ENVELOPE GLYCOPROTEIN DETERMINED BY CRYO-ELECTRON MICROSCOPY | | Descriptor: | GP41, GP120, MONOCLONAL ANTIBODY VRC03 FAB HEAVY CHAIN, ... | | Authors: | Bartesaghi, A., Merk, A., Borgnia, M.J., Milne, J.L.S., Subramaniam, S. | | Deposit date: | 2013-10-18 | | Release date: | 2013-10-30 | | Last modified: | 2018-01-10 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy.
Nat.Struct.Mol.Biol., 20, 2013
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5A1A | | 2.2 A RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE IN COMPLEX WITH A CELL-PERMEANT INHIBITOR | | Descriptor: | BETA-GALACTOSIDASE, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ... | | Authors: | Bartesaghi, A., Merk, A., Banerjee, S., Matthies, D., Wu, X., Milne, J., Subramaniam, S. | | Deposit date: | 2015-04-29 | | Release date: | 2015-05-06 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | 2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
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2YNJ | | GROEL AT SUB-NANOMETER RESOLUTION BY CONSTRAINED SINGLE PARTICLE TOMOGRAPHY | | Descriptor: | 60 KDA CHAPERONIN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, THALLIUM (I) ION, ... | | Authors: | Bartesaghi, A., Lecumberry, F., Sapiro, G., Subramaniam, S. | | Deposit date: | 2012-10-15 | | Release date: | 2012-12-12 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (8.4 Å) | | Cite: | Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography
Structure, 20, 2012
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6CVM | | ATOMIC RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE | | Descriptor: | Beta-galactosidase, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ... | | Authors: | Subramaniam, S., Bartesaghi, A., Banerjee, S., Zhu, X., Milne, J.L.S. | | Deposit date: | 2018-03-28 | | Release date: | 2018-05-30 | | Last modified: | 2018-08-22 | | Method: | ELECTRON MICROSCOPY (1.9 Å) | | Cite: | Atomic Resolution Cryo-EM Structure of beta-Galactosidase.
Structure, 26, 2018
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3JCZ | | STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-27 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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3JD0 | | GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-28 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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3JD1 | | GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-28 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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3JD2 | | GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-28 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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3JD3 | | GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-28 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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3JD4 | | GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | Authors: | Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S. | | Deposit date: | 2016-03-28 | | Release date: | 2016-04-27 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
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5FTJ | | CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO UPCDC30245 INHIBITOR | | Descriptor: | TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE, 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE | | Authors: | Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S. | | Deposit date: | 2016-01-14 | | Release date: | 2016-01-27 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
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5FTK | | CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ADP | | Descriptor: | TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S. | | Deposit date: | 2016-01-14 | | Release date: | 2016-01-27 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
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5FTL | | CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | | Descriptor: | TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S. | | Deposit date: | 2016-01-14 | | Release date: | 2016-01-27 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
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5FTM | | CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | | Descriptor: | TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S. | | Deposit date: | 2016-01-14 | | Release date: | 2016-01-27 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
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5FTN | | CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION III) | | Descriptor: | TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION | | Authors: | Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S. | | Deposit date: | 2016-01-14 | | Release date: | 2016-01-27 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
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5K0Z | | CRYO-EM STRUCTURE OF LACTATE DEHYDROGENASE (LDH) IN INHIBITOR-BOUND STATE | | Descriptor: | L-lactate dehydrogenase B chain | | Authors: | Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S. | | Deposit date: | 2016-05-17 | | Release date: | 2016-06-08 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
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5K10 | | CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1) | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S. | | Deposit date: | 2016-05-17 | | Release date: | 2016-06-08 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
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5K11 | | CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1) IN INHIBITOR-BOUND STATE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S. | | Deposit date: | 2016-05-17 | | Release date: | 2016-06-08 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
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5K12 | | CRYO-EM STRUCTURE OF GLUTAMATE DEHYDROGENASE AT 1.8 A RESOLUTION | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial | | Authors: | Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S. | | Deposit date: | 2016-05-17 | | Release date: | 2016-06-08 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (1.8 Å) | | Cite: | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
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6B44 | | CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND TARGET DSDNA | | Descriptor: | CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... | | Authors: | Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S. | | Deposit date: | 2017-09-25 | | Release date: | 2017-10-18 | | Last modified: | 2020-01-01 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B45 | | CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX | | Descriptor: | CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... | | Authors: | Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S. | | Deposit date: | 2017-09-25 | | Release date: | 2017-10-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B46 | | CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF1 | | Descriptor: | CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ... | | Authors: | Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S. | | Deposit date: | 2017-09-25 | | Release date: | 2017-10-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B47 | | CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF2 | | Descriptor: | CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... | | Authors: | Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S. | | Deposit date: | 2017-09-25 | | Release date: | 2017-10-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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6B48 | | CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF10 | | Descriptor: | CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... | | Authors: | Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S. | | Deposit date: | 2017-09-25 | | Release date: | 2017-10-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
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