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2KWT
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BU of 2kwt by Molmil
Solution structure of NS2 [27-59]
Descriptor: Protease NS2-3
Authors:Montserret, R, Bartenschlager, R, Penin, F.
Deposit date:2010-04-19
Release date:2011-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.
Plos Pathog., 6, 2010
2KWZ
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BU of 2kwz by Molmil
Solution structure of NS2 [60-99]
Descriptor: Protease NS2-3
Authors:Montserret, R, Bartenschlager, R, Penin, F.
Deposit date:2010-04-22
Release date:2011-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.
Plos Pathog., 6, 2010
1R7E
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BU of 1r7e by Molmil
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Minimized average structure. Sample in 100mM SDS).
Descriptor: Genome polyprotein
Authors:Penin, F, Brass, V, Appel, N, Ramboarina, S, Montserret, R, Ficheux, D, Blum, H.E, Bartenschlager, R, Moradpour, D.
Deposit date:2003-10-21
Release date:2004-08-10
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
J.Biol.Chem., 279, 2004
1R7C
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BU of 1r7c by Molmil
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Minimized average structure, Sample in 50% tfe)
Descriptor: Genome polyprotein
Authors:Penin, F, Brass, V, Appel, N, Ramboarina, S, Montserret, R, Ficheux, D, Blum, H.E, Bartenschlager, R, Moradpour, D.
Deposit date:2003-10-21
Release date:2004-08-10
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
J.Biol.Chem., 279, 2004
1R7F
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BU of 1r7f by Molmil
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Ensemble of 43 structures. Sample in 100mM SDS)
Descriptor: Genome polyprotein
Authors:Penin, F, Brass, V, Appel, N, Ramboarina, S, Montserret, R, Ficheux, D, Blum, H.E, Bartenschlager, R, Moradpour, D.
Deposit date:2003-10-21
Release date:2004-08-10
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
J.Biol.Chem., 279, 2004
1R7G
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BU of 1r7g by Molmil
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Minimized average structure, Sample in 100mM DPC)
Descriptor: Genome polyprotein
Authors:Penin, F, Brass, V, Appel, N, Ramboarina, S, Montserret, R, Ficheux, D, Blum, H.E, Bartenschlager, R, Moradpour, D.
Deposit date:2003-10-21
Release date:2004-08-10
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
J.Biol.Chem., 279, 2004
1R7D
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BU of 1r7d by Molmil
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Ensemble of 51 structures, sample in 50% tfe)
Descriptor: Genome polyprotein
Authors:Penin, F, Brass, V, Appel, N, Ramboarina, S, Montserret, R, Ficheux, D, Blum, H.E, Bartenschlager, R, Moradpour, D.
Deposit date:2003-10-21
Release date:2004-08-10
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
J.Biol.Chem., 279, 2004
5IDK
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BU of 5idk by Molmil
Crystal structure of West Nile Virus NS2B-NS3 protease in complex with a capped dipeptide boronate inhibitor
Descriptor: ((R)-1-((S)-3-(4-(aminomethyl)phenyl)-2-benzamidopropaneamido)-4-guanidinobutyl)boronic acid, cyclic double ester with glycerol, DIMETHYL SULFOXIDE, ...
Authors:Hilgenfeld, R, Zhang, L.
Deposit date:2016-02-24
Release date:2016-12-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology.
J. Med. Chem., 60, 2017
2LVG
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BU of 2lvg by Molmil
NMR structure of HCV Non-structural protein AB, NS4B(1-40)
Descriptor: Non-structural protein 4B
Authors:Montserret, R, Penin, F.
Deposit date:2012-07-05
Release date:2013-06-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Aminoterminal Amphipathic alpha-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production.
Plos Pathog., 10, 2014
8C0O
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BU of 8c0o by Molmil
African cichlid nackednavirus capsid at pH 5.5
Descriptor: C protein
Authors:Pfister, S, Rabl, J, Boehringer, D, Meier, B.H.
Deposit date:2022-12-19
Release date:2023-04-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style.
Nat Commun, 14, 2023
6HT4
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BU of 6ht4 by Molmil
NMR Structure of NS5A-D2 (JFH1) peptide (304-323)
Descriptor: NS5A
Authors:Dujardin, M, Cantrelle, F.X, Lippens, G, Hanoulle, X.
Deposit date:2018-10-03
Release date:2019-07-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.
J.Biol.Chem., 294, 2019
8AAC
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BU of 8aac by Molmil
African cichlid nackednavirus capsid at pH 7.5
Descriptor: C protein
Authors:Pfister, S, Rabl, J, Boehringer, D, Meier, B.H.
Deposit date:2022-07-01
Release date:2023-04-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style.
Nat Commun, 14, 2023
2XXD
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BU of 2xxd by Molmil
HCV-JFH1 NS5B polymerase structure at 1.9 angstrom
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Caillet-Saguy, C, Bressanelli, S.
Deposit date:2010-11-10
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2XYM
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BU of 2xym by Molmil
HCV-JFH1 NS5B T385A mutant
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Simister, P.C, Caillet-Saguy, C, Bressanelli, S.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2XWH
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BU of 2xwh by Molmil
HCV-J6 NS5B polymerase structure at 1.8 Angstrom
Descriptor: DI(HYDROXYETHYL)ETHER, POLYETHYLENE GLYCOL (N=34), RNA DEPENDENT RNA POLYMERASE
Authors:Scrima, N, Bressanelli, S.
Deposit date:2010-11-03
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2JY0
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BU of 2jy0 by Molmil
Solution NMR structure of HCV NS2 protein, membrane segment (1-27)
Descriptor: Protease NS2-3
Authors:Montserret, R, Penin, F.
Deposit date:2007-12-04
Release date:2008-09-16
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural and functional characterization of non-structural protein 2 for its role in hepatitis C virus assembly
J.Biol.Chem., 2008
6YD7
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BU of 6yd7 by Molmil
X-ray structure of furin in complex with the canavanine-based inhibitor 4-guanidinomethyl-phenylacetyl-Arg-Tle-Canavanine-Amba
Descriptor: 4-guanidinomethyl-phenylacetyl-Arg-Tle-Canavanine-Amba, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2020-03-20
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.
Acs Med.Chem.Lett., 12, 2021
6YD4
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BU of 6yd4 by Molmil
X-ray structure of furin in complex with the canavanine-based inhibitor 4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Canavanine-Amba
Descriptor: 4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Canavanine-Amba, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2020-03-20
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.
Acs Med.Chem.Lett., 12, 2021
6YD3
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BU of 6yd3 by Molmil
X-ray structure of furin in complex with the canavanine derived inhibitor 4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Arg-Amba
Descriptor: 4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Arg-Amba, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2020-03-20
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.
Acs Med.Chem.Lett., 12, 2021
6YD2
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BU of 6yd2 by Molmil
X-ray structure of furin in complex with the canavanine-based inhibitor 4-aminomethyl-phenylacetyl-canavanine-Tle-Arg-Amba
Descriptor: 4-aminomethyl-phenylacetyl-canavanine-Tle-Arg-Amba, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2020-03-20
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.
Acs Med.Chem.Lett., 12, 2021
6ZWV
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BU of 6zwv by Molmil
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: 3 Closed RBDs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Ke, Z, Qu, K, Nakane, T, Xiong, X, Cortese, M, Zila, V, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-28
Release date:2020-08-05
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Nature, 588, 2020

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