6HT4

NMR Structure of NS5A-D2 (JFH1) peptide (304-323)

Summary for 6HT4

• Entry DOI: 10.2210/pdb6ht4/pdb
• NMR Information: BMRB: 30037
• Descriptor: NS5A (1 entity in total)
• Functional Keywords: pw-turn, unknown function
• Biological source: Hepacivirus C
• Total number of polymer chains: 1
• Total formula weight: 2268.57

Authors

Dujardin, M.,Cantrelle, F.X.,Lippens, G.,Hanoulle, X. (deposition date: 2018-10-03, release date: 2019-07-24, Last modification date: 2023-06-14)

• Primary citation: Dujardin, M.,Madan, V.,Gandhi, N.S.,Cantrelle, F.X.,Launay, H.,Huvent, I.,Bartenschlager, R.,Lippens, G.,Hanoulle, X.; Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.; J.Biol.Chem., 294:13171-13185, 2019; PubMed: 31315928; DOI: 10.1074/jbc.RA119.009537

Experimental method

SOLUTION NMR