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4UCE
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BU of 4uce by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M72
Descriptor: 1-[(4-fluorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCC
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BU of 4ucc by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M76
Descriptor: 1-[(2,4-dichlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC6
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BU of 4uc6 by Molmil
N-terminal globular domain of the RSV Nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC7
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BU of 4uc7 by Molmil
N-terminal globular domain of the RSV Nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCB
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BU of 4ucb by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
Descriptor: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCD
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BU of 4ucd by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M81
Descriptor: 1-[(2-chlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC9
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BU of 4uc9 by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal dipeptide of the Phosphoprotein
Descriptor: ASPARTIC ACID, NUCLEOPROTEIN, PHENYLALANINE, ...
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCA
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BU of 4uca by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
Descriptor: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC8
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BU of 4uc8 by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal phenylalanine of the Phosphoprotein
Descriptor: GLYCEROL, NUCLEOPROTEIN, PHENYLALANINE, ...
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
5JBS
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BU of 5jbs by Molmil
Conformational changes during monomer-to-dimer transition of Brucella suis VirB8
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Arya, T, Sharifahmadian, M, Sygusch, J, Baron, B.
Deposit date:2016-04-13
Release date:2017-03-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:NMR analyses, X-ray crystallography and small-molecule probing reveal conformational shifts during monomer-to-dimer transition of Brucella suis VirB8
To Be Published
4A56
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BU of 4a56 by Molmil
Crystal structure of the type 2 secretion system pilotin from Klebsiella Oxytoca
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, PULLULANASE SECRETION PROTEIN PULS
Authors:Tosi, T, Nickerson, N.N, Mollica, L, RingkjobingJensen, M, Blackledge, M, Baron, B, England, P, Pugsley, A.P, Dessen, A.
Deposit date:2011-10-24
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Pilotin-Secretin Recognition in the Type II Secretion System of Klebsiella Oxytoca.
Mol.Microbiol, 82, 2011
7BES
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BU of 7bes by Molmil
CryoEM structure of Mycobacterium tuberculosis UMP Kinase (UMPK) in complex with UDP and UTP
Descriptor: URIDINE 5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE, Uridylate kinase
Authors:Bous, J, Trapani, S, Walter, P, Bron, P, Munier-Lehmann, H.
Deposit date:2020-12-24
Release date:2022-01-12
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Febs J., 289, 2022
7PC6
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BU of 7pc6 by Molmil
DNA-binding domain of a p53 homolog from the hydrothermal vent annelid Alvinella pompejana
Descriptor: 1,2-ETHANEDIOL, DNA-binding domain, ZINC ION
Authors:Balourdas, D.-I, Knapp, S, Soussi, T, Joerger, A.C, Structural Genomics Consortium (SGC)
Deposit date:2021-08-03
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.
Cell Death Dis, 13, 2022
3NPZ
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BU of 3npz by Molmil
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
Descriptor: Prolactin, Prolactin receptor
Authors:Van Agthoven, J, England, P, Goffin, V, Broutin, I.
Deposit date:2010-06-29
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
6HKS
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BU of 6hks by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Descriptor: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Haouz, A, Caillet-Saguy, C.
Deposit date:2018-09-07
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1944108 Å)
Cite:Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
2Y8D
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BU of 2y8d by Molmil
STRUCTURE OF DBL6 EPSILON DOMAIN FROM VAR2CSA STRAIN FCR3
Descriptor: 2-AMINO-ETHANETHIOL, BENZAMIDINE, ERYTHROCYTE MEMBRANE PROTEIN 1
Authors:Gangnard, S, Ramboarina, S, Lewit-Bentley, A, Bentley, G.A.
Deposit date:2011-02-04
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural and Immunological Correlations between the Variable Blocks of the Var2Csa Domain Dbl6Epsilon from Two Plasmodium Falciparum Parasite Lines.
J.Mol.Biol., 425, 2013
5JCY
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BU of 5jcy by Molmil
Spir2-GTBM bound to MyoVa-GTD
Descriptor: Protein spire homolog 2, Unconventional myosin-Va
Authors:Pylypenko, O, Malherbes, G, Welz, T, Kerkhoff, E, Houdusse, A.
Deposit date:2016-04-15
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
5JCZ
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BU of 5jcz by Molmil
Rab11 bound to MyoVa-GTD
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Pylypenko, O, Attanda, W, Gauquelin, C, Malherbes, G, Houdusse, A.
Deposit date:2016-04-15
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
7BL7
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BU of 7bl7 by Molmil
Crystal structure of UMPK from M. tuberculosis in complex with UDP and UTP (P21212 form)
Descriptor: URIDINE 5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE, Uridylate kinase
Authors:Walter, P, Labesse, G, Haouz, A, Mechaly, A.E, Munier-Lehmann, H.
Deposit date:2021-01-18
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Febs J., 289, 2022
7BIX
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BU of 7bix by Molmil
Crystal structure of UMPK from M. tuberculosis in complex with UDP and UTP (C2 form)
Descriptor: URIDINE 5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE, Uridylate kinase
Authors:Labesse, G, Walter, P, Haouz, A, Mechaly, A.E, Munier-Lehmann, H.
Deposit date:2021-01-13
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Febs J., 289, 2022
2XU0
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BU of 2xu0 by Molmil
Crystal structure of the NTS-DBL1(alpha-1) domain of the Plasmodium falciparum membrane protein 1 (PfEMP1) from the varO strain.
Descriptor: ERYTHROCYTE MEMBRANE PROTEIN 1, GLYCEROL, MAGNESIUM ION, ...
Authors:Juillerat, A, Lewit-Bentley, A, Guillotte, M, Vigan-Womas, I, Hessler, A, Gangnard, S, England, P, Mercereau-Puijalon, O, Bentley, G.A.
Deposit date:2010-10-14
Release date:2011-04-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition.
Proc.Natl.Acad.Sci.USA, 108, 2011
6RX1
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BU of 6rx1 by Molmil
Crystal structure of human syncytin 1 in post-fusion conformation
Descriptor: CHLORIDE ION, GLYCEROL, Syncytin-1
Authors:Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A.
Deposit date:2019-06-07
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
6RX3
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BU of 6rx3 by Molmil
Crystal structure of human syncytin 2 in post-fusion conformation
Descriptor: CHLORIDE ION, Syncytin-2
Authors:Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A.
Deposit date:2019-06-07
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
4LX0
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BU of 4lx0 by Molmil
Crystal structure of Myo5b globular tail domain in complex with active Rab11a
Descriptor: BERYLLIUM TRIFLUORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LWZ
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BU of 4lwz by Molmil
Crystal structure of Myo5b globular tail domain in complex with inactive Rab11a
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-11A, ...
Authors:Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013

 

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