4UCC
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M76
Summary for 4UCC
Entry DOI | 10.2210/pdb4ucc/pdb |
Related | 4UC6 4UC7 4UC8 4UC9 4UCA 4UCB 4UCD 4UCE |
Descriptor | NUCLEOPROTEIN, 1-[(2,4-dichlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid (3 entities in total) |
Functional Keywords | viral protein, respiratory syncytial virus, ribonucleoprotein, nucleocapsid, phosphoprotein, antiviral compounds, halogen bond |
Biological source | HUMAN RESPIRATORY SYNCYTIAL VIRUS A2 |
Cellular location | Virion: P03418 |
Total number of polymer chains | 2 |
Total formula weight | 53162.85 |
Authors | Ouizougun-Oubari, M.,Pereira, N.,Tarus, B.,Galloux, M.,Tortorici, M.-A.,Hoos, S.,Baron, B.,England, P.,Bontems, F.,Rey, F.A.,Eleouet, J.-F.,Sizun, C.,Slama-Schwok, A.,Duquerroy, S. (deposition date: 2014-12-03, release date: 2015-08-19, Last modification date: 2023-12-20) |
Primary citation | Ouizougun-Oubari, M.,Pereira, N.,Tarus, B.,Galloux, M.,Lassoued, S.,Fix, J.,Tortorici, M.A.,Hoos, S.,Baron, B.,England, P.,Desmaele, D.,Couvreur, P.,Bontems, F.,Rey, F.A.,Eleouet, J.F.,Sizun, C.,Slama-Schwok, A.,Duquerroy, S. A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89:11129-, 2015 Cited by PubMed: 26246564DOI: 10.1128/JVI.01612-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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