4UCD

N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M81

Summary for 4UCD

Entry DOI	10.2210/pdb4ucd/pdb
Related	4UC6 4UC7 4UC8 4UC9 4UCA 4UCB 4UCC 4UCE
Descriptor	NUCLEOPROTEIN, 1-[(2-chlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	viral protein, respiratory syncytial virus, ribonucleoprotein, nucleocapsid, phosphoprotein, antiviral compounds, halogen bond
Biological source	HUMAN RESPIRATORY SYNCYTIAL VIRUS A2
Cellular location	Virion: P03418
Total number of polymer chains	2
Total formula weight	53190.02
Authors	Ouizougun-Oubari, M.,Pereira, N.,Tarus, B.,Galloux, M.,Tortorici, M.-A.,Hoos, S.,Baron, B.,England, P.,Bontems, F.,Rey, F.A.,Eleouet, J.-F.,Sizun, C.,Slama-Schwok, A.,Duquerroy, S. (deposition date: 2014-12-03, release date: 2015-08-19, Last modification date: 2023-12-20)
Primary citation	Ouizougun-Oubari, M.,Pereira, N.,Tarus, B.,Galloux, M.,Lassoued, S.,Fix, J.,Tortorici, M.A.,Hoos, S.,Baron, B.,England, P.,Desmaele, D.,Couvreur, P.,Bontems, F.,Rey, F.A.,Eleouet, J.F.,Sizun, C.,Slama-Schwok, A.,Duquerroy, S. A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89:11129-, 2015 Cited by PubMed: 26246564 DOI: 10.1128/JVI.01612-15 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.66 Å)

Structure validation