Author results

1H8B
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EF-HANDS 3,4 FROM ALPHA-ACTININ / Z-REPEAT 7 FROM TITIN
Descriptor:ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
Authors:Atkinson, R.A., Joseph, C., Kelly, G., Muskett, F.W., Frenkiel, T.A., Nietlispach, D., Pastore, A.
Deposit date:2001-02-01
Release date:2001-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
1DW4
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NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: CONSTRAINTS ON DISULPHIDE BRIDGES
Descriptor:OMEGA-CONOTOXIN MVIIA
Authors:Atkinson, R.A., Kieffer, B., Dejaegere, A., Sirockin, F., Lefevre, J.-F.
Deposit date:2000-01-24
Release date:2000-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange.
Biochemistry, 39, 2000
1DW5
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NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: NO CONSTRAINTS ON DISULPHIDE BRIDGES
Descriptor:OMEGA-CONOTOXIN MVIIA
Authors:Atkinson, R.A., Kieffer, B., Dejaegere, A., Sirockin, F., Lefevre, J.-F.
Deposit date:2000-01-24
Release date:2000-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange.
Biochemistry, 39, 2000
2ECH
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ECHISTATIN-THE REFINED STRUCTURE OF A DISINTEGRIN IN SOLUTION BY 1H NMR
Descriptor:ECHISTATIN
Authors:Pelton, J.T., Atkinson, R.A., Saudek, V.
Deposit date:1993-04-13
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Echistatin: the refined structure of a disintegrin in solution by 1H NMR and restrained molecular dynamics.
Int.J.Pept.Protein Res., 43, 1994
2KPK
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MAGI-1 PDZ1
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Authors:Charbonnier, S., Nomine, Y., Ramirez, J., Luck, K., Stote, R.H., Trave, G., Kieffer, B., Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
1RGW
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SOLUTION STRUCTURE OF ZASP'S PDZ DOMAIN
Descriptor:ZASP protein
Authors:Au, Y., Atkinson, R.A., Pallavicini, A., Joseph, C., Martin, S.R., Muskett, F.W., Guerrini, R., Faulkner, G., Pastore, A.
Deposit date:2003-11-13
Release date:2004-04-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy.
Structure, 12, 2004
2JNJ
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SOLUTION STRUCTURE OF THE P8 TFIIH SUBUNIT
Descriptor:TFIIH basal transcription factor complex TTD-A subunit
Authors:Vitorino, M., Atkinson, R.A., Moras, D., Poterszman, A., Kieffer, B.
Deposit date:2007-01-26
Release date:2007-04-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Self-association Properties of the p8 TFIIH Subunit Responsible for Trichothiodystrophy
J.Mol.Biol., 368, 2007
2KPL
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MAGI-1 PDZ1 / E6CT
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6
Authors:Charbonnier, S., Nomine, Y., Ramirez, J., Luck, K., Stote, R.H., Trave, G., Kieffer, B., Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
2MA9
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HIV-1 VIF SOCS-BOX AND ELONGIN BC SOLUTION STRUCTURE
Descriptor:Virion infectivity factor, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1
Authors:Lu, Z., Bergeron, J.R., Atkinson, R.A., Schaller, T., Veselkov, D.A., Oregioni, A., Yang, Y., Matthews, S.J., Malim, M.H., Sanderson, M.R.
Deposit date:2013-07-01
Release date:2013-12-11
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction.
OPEN BIOLOGY, 3, 2013
3ZTG
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SOLUTION STRUCTURE OF THE RING FINGER-LIKE DOMAIN OF RETINOBLASTOMA BINDING PROTEIN-6 (RBBP6)
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE RBBP6, ZINC ION
Authors:Kappo, M.A., Ab, E., Atkinson, R.A., Faro, A., Muleya, V., Mulaudzi, T., Poole, J.O., McKenzie, J.M., Pugh, D.J.R.
Deposit date:2011-07-07
Release date:2011-12-07
Last modified:2012-03-14
Method:SOLUTION NMR
Cite:Solution Structure of the Ring Finger-Like Domain of Retinoblastoma Binding Protein-6 (Rbbp6) Suggests It Functions as a U-Box
J.Biol.Chem., 287, 2012
6I9B
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NMR STRUCTURE OF THE LA MODULE FROM HUMAN LARP4A
Descriptor:La-related protein 4
Authors:Conte, M.R., Martino, L., Atkinson, R.A., Kelly, G., Cruz-Gallardo, i., De Tito, S., Trotta, R.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
2MTF
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SOLUTION STRUCTURE OF THE LA MOTIF OF HUMAN LARP6
Descriptor:La-related protein 6
Authors:Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R.
Deposit date:2014-08-18
Release date:2014-12-24
Last modified:2015-01-28
Method:SOLUTION NMR
Cite:Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
2MTG
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SOLUTION STRUCTURE OF THE RRM1 OF HUMAN LARP6
Descriptor:La-related protein 6
Authors:Martino, L., Atkinson, A.R., Kelly, G., Conte, M.R.
Deposit date:2014-08-18
Release date:2014-12-24
Last modified:2015-01-28
Method:SOLUTION NMR
Cite:Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
5N7Y
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SOLUTION STRUCTURE OF B. SUBTILIS SIGMA G INHIBITOR CSFB
Descriptor:Anti-sigma-G factor Gin, ZINC ION
Authors:Martinez-Lumbreras, S., Alfano, C., Atkinson, A., Isaacson, R.L.
Deposit date:2017-02-21
Release date:2018-02-28
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structural and Functional Insights into Bacillus subtilis Sigma Factor Inhibitor, CsfB.
Structure, 26, 2018
2FK4
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SOLUTION STRUCTURE OF THE C-TERMINAL ZINC BINDING DOMAIN OF THE HPV16 E6 ONCOPROTEIN
Descriptor:Protein E6, ZINC ION
Authors:Nomine, Y., Charbonnier, S.
Deposit date:2006-01-04
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis
Mol.Cell, 21, 2006
4LOO
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STRUCTURAL BASIS OF AUTOACTIVATION OF P38 ALPHA INDUCED BY TAB1 (MONOCLINIC CRYSTAL FORM)
Descriptor:Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE
Authors:Chaikuad, A., DeNicola, G.F., Krojer, T., Allerston, C.K., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Marber, M.S., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2013-07-13
Release date:2013-08-21
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
4LOP
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STRUCTURAL BASIS OF AUTOACTIVATION OF P38 ALPHA INDUCED BY TAB1 (TETRAGONAL CRYSTAL FORM)
Descriptor:Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, ...
Authors:Chaikuad, A., DeNicola, G.F., Krojer, T., Allerston, C.K., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Marber, M.S., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2013-07-13
Release date:2013-08-21
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
4LOQ
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STRUCTURAL BASIS OF AUTOACTIVATION OF P38 ALPHA INDUCED BY TAB1 (TETRAGONAL CRYSTAL FORM WITH BOUND SULPHATE)
Descriptor:Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, ...
Authors:Chaikuad, A., DeNicola, G.F., Yue, W.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Marber, M.S., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2013-07-13
Release date:2013-08-21
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.319 Å)
Cite:Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
6GIJ
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NMR STRUCTURE OF TEMPORIN B KKG6A IN SDS MICELLES
Descriptor:temporinB_KKG6A
Authors:Manzo, G., Mason, J.A.
Deposit date:2018-05-12
Release date:2018-06-13
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity.
Sci Rep, 9, 2019
6GIK
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NMR STRUCTURE OF TEMPORIN B L1FK IN SDS MICELLES
Descriptor:temporinB_L1FK
Authors:Manzo, G., Mason, J.A.
Deposit date:2018-05-12
Release date:2018-06-13
Last modified:2019-09-11
Method:SOLUTION NMR
Cite:Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity.
Sci Rep, 9, 2019
6GIL
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NMR STRUCTURE OF TEMPORIN B IN SDS MICELLES
Descriptor:Temporin-B
Authors:Manzo, G., Mason, J.A.
Deposit date:2018-05-12
Release date:2018-06-13
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity.
Sci Rep, 9, 2019
6GS5
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NMR STRUCTURE OF TEMPORIN L IN SDS MICELLES
Descriptor:Temporin-L
Authors:Manzo, G., Mason, J.A.
Deposit date:2018-06-13
Release date:2018-07-18
Last modified:2019-08-14
Method:SOLUTION NMR
Cite:Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities.
Sci Rep, 9, 2019
6GS9
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NMR STRUCTURE OF AUREIN 2.5 IN SDS MICELLES
Descriptor:Aurein 2.5
Authors:Manzo, G., Mason, J.A.
Deposit date:2018-06-13
Release date:2018-07-18
Last modified:2019-08-14
Method:SOLUTION NMR
Cite:Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities.
Sci Rep, 9, 2019
6I5E
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X-RAY STRUCTURE OF APO HUMAN SOLUBLE EPOXIDE HYDROLASE C-TERMINAL DOMAIN (HSEH CTD)
Descriptor:Bifunctional epoxide hydrolase 2
Authors:Abis, G., Kopec, J., Yue, W.W., Conte, M.R.
Deposit date:2018-11-13
Release date:2019-05-29
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.
Commun Biol, 2, 2019
6I5G
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X-RAY STRUCTURE OF HUMAN SOLUBLE EPOXIDE HYDROLASE C-TERMINAL DOMAIN (HSEH CTD)IN COMPLEX WITH 15D-PGJ2
Descriptor:Bifunctional epoxide hydrolase 2, 1,2-ETHANEDIOL, (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid
Authors:Abis, G., Kopec, J., Yue, W.W., Conte, M.R.
Deposit date:2018-11-13
Release date:2019-05-29
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.
Commun Biol, 2, 2019
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