1J1B | | BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH AMPPNP | | Descriptor: | Glycogen synthase kinase-3 beta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T. | | Deposit date: | 2002-12-03 | | Release date: | 2003-12-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
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1J1C | | BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH ADP | | Descriptor: | Glycogen synthase kinase-3 beta, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T. | | Deposit date: | 2002-12-03 | | Release date: | 2003-12-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
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5COK | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-0476 | | Descriptor: | HIV-1 protease, (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2015-07-20 | | Release date: | 2016-01-13 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
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5CON | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-015 | | Descriptor: | HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2015-07-20 | | Release date: | 2016-01-13 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
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5COO | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-085 | | Descriptor: | HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-1-(4-methoxyphenyl)-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2015-07-20 | | Release date: | 2016-01-13 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
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5COP | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-097 | | Descriptor: | HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-(4-methoxyphenyl)butan-2-yl]carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2015-07-20 | | Release date: | 2016-01-13 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
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5TYR | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-121 | | Descriptor: | Protease, (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2016-11-21 | | Release date: | 2017-10-18 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
Elife, 6, 2017
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5TYS | | X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-142 | | Descriptor: | Protease, (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate | | Authors: | Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H. | | Deposit date: | 2016-11-21 | | Release date: | 2017-10-18 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (2.007 Å) | | Cite: | A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
Elife, 6, 2017
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1VDY | | NMR STRUCTURE OF THE HYPOTHETICAL ENTH-VHS DOMAIN AT3G16270 FROM ARABIDOPSIS THALIANA | | Descriptor: | hypothetical protein (RAFL09-17-B18) | | Authors: | Lopez-Mendez, B., Pantoja-Uceda, D., Tomizawa, T., Koshiba, S., Kigawa, T., Shirouzu, M., Terada, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Seki, M., Shinozaki, K., Yokoyama, S., Guntert, P., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-03-25 | | Release date: | 2005-05-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the hypothetical ENTH-VHS domain AT3G16270 from arabidopsis thaliana
To be Published
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1UFN | | SOLUTION STRUCTURE OF THE SAND DOMAIN OF THE PUTATIVE NUCLEAR PROTEIN HOMOLOG (5830484A20RIK) | | Descriptor: | putative nuclear protein homolog 5830484A20Rik | | Authors: | Tochio, N., Kobayashi, N., Koshiba, S., Kigawa, T., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-02 | | Release date: | 2004-06-22 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
To be Published
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1UFW | | SOLUTION STRUCTURE OF RNP DOMAIN IN SYNAPTOJANIN 2 | | Descriptor: | Synaptojanin 2 | | Authors: | He, F., Muto, Y., Ushikoshi, R., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-10 | | Release date: | 2003-12-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RNP domain in Synaptojanin 2
To be Published
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1UFX | | SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMAN KIAA1526 PROTEIN | | Descriptor: | KIAA1526 protein | | Authors: | Tochio, N., Kobayashi, N., Koshiba, S., Kigawa, T., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-10 | | Release date: | 2003-12-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the third PDZ domain of human KIAA1526 protein
To be Published
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1UFZ | | SOLUTION STRUCTURE OF HBS1-LIKE DOMAIN IN HYPOTHETICAL PROTEIN BAB28515 | | Descriptor: | Hypothetical protein BAB28515 | | Authors: | He, F., Muto, Y., Hayami, N., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2004-08-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of HBS1-like domain in hypothetical protein BAB28515
To be Published
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1UG0 | | SOLUTION STRUCTURE OF SURP DOMAIN IN BAB30904 | | Descriptor: | splicing factor 4 | | Authors: | He, F., Muto, Y., Ushikoshi, R., Koshiba, S., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2004-08-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of SURP domain in BAB30904
To be Published
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1UG1 | | SH3 DOMAIN OF HYPOTHETICAL PROTEIN BAA76854.1 | | Descriptor: | KIAA1010 protein | | Authors: | Nagata, T., Muto, Y., Kamewari, Y., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2003-12-11 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of SH3 domain of Hypothetical protein BAA76854.1
To be Published
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1UG2 | | SOLUTION STRUCTURE OF MOUSE HYPOTHETICAL GENE (2610100B20RIK) PRODUCT HOMOLOGOUS TO MYB DNA-BINDING DOMAIN | | Descriptor: | 2610100B20Rik gene product | | Authors: | Zhao, C., Kigawa, T., Tochio, N., Koshiba, S., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2004-06-22 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
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1UG7 | | SOLUTION STRUCTURE OF FOUR HELICAL UP-AND-DOWN BUNDLE DOMAIN OF THE HYPOTHETICAL PROTEIN 2610208M17RIK SIMILAR TO THE PROTEIN FLJ12806 | | Descriptor: | 2610208M17Rik protein | | Authors: | Li, H., Kigawa, T., Tomizawa, T., Koshiba, S., Inoue, M., Shirouzu, M., Terada, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-13 | | Release date: | 2004-08-17 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
To be Published
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1UG8 | | NMR STRUCTURE OF THE R3H DOMAIN FROM POLY(A)-SPECIFIC RIBONUCLEASE | | Descriptor: | Poly(A)-specific Ribonuclease | | Authors: | Nagata, T., Muto, Y., Hayami, N., Uda, H., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-15 | | Release date: | 2004-08-17 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the R3H domain from Poly(A)-specific Ribonuclease
To be Published
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1UGJ | | SOLUTION STRUCTURE OF A MURINE HYPOTHETICAL PROTEIN FROM RIKEN CDNA 2310057J16 | | Descriptor: | RIKEN cDNA 2310057J16 protein | | Authors: | Nagashima, T., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-16 | | Release date: | 2004-08-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
To be Published
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1UGK | | SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF SYNAPTOTAGMIN IV FROM HUMAN FETAL BRAIN (KIAA1342) | | Descriptor: | Synaptotagmin IV | | Authors: | Nagashima, T., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-16 | | Release date: | 2003-12-16 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)
To be Published
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1UGV | | SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMAN OLYGOPHREIN-1 LIKE PROTEIN (KIAA0621) | | Descriptor: | Olygophrenin-1 like protein | | Authors: | Inoue, K., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-20 | | Release date: | 2003-12-20 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)
To be Published
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1UH6 | | SOLUTION STRUCTURE OF THE MURINE UBIQUITIN-LIKE 5 PROTEIN FROM RIKEN CDNA 0610031K06 | | Descriptor: | ubiquitin-like 5 | | Authors: | Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-25 | | Release date: | 2003-12-25 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
To be Published
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1UHR | | SOLUTION STRUCTURE OF THE SWIB DOMAIN OF MOUSE BRG1-ASSOCIATED FACTOR 60A | | Descriptor: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily D member 1 | | Authors: | Yamada, K., Saito, K., Nameki, N., Inoue, M., Koshiba, S., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Matsuda, T., Seki, E., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-07-09 | | Release date: | 2004-08-24 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
To be Published
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1UHS | | SOLUTION STRUCTURE OF MOUSE HOMEODOMAIN-ONLY PROTEIN HOP | | Descriptor: | homeodomain only protein | | Authors: | Saito, K., Koshiba, S., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Matsuda, T., Seki, E., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-07-10 | | Release date: | 2004-07-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of mouse homeodomain-only protein HOP
To be Published
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1UHT | | SOLUTION STRUCTURE OF THE FHA DOMAIN OF ARABIDOPSIS THALIANA HYPOTHETICAL PROTEIN | | Descriptor: | expressed protein | | Authors: | Tomizawa, T., Inoue, M., Koshiba, S., Hayashi, F., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Matsuda, T., Seki, E., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Shinozaki, K., Seki, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-07-10 | | Release date: | 2004-01-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein
To be Published
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